Mallet, Jacques

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Lee, P. H., Anttila, V., Won, H., Feng, Y.-C. A., Rosenthal, J., Zhu, Z., Tucker-Drob, E. M., Nivard, M. G., Grotzinger, A. D., Posthuma, D., et al. (2019) · Cell

Genetic Associations and EpidemiologySchizophrenia research and treatment

Cited by 1,381

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., et al. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,303

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

Maskos, U., Molles, B. E., Pons, S., Besson, M., Guiard, B. P., Guilloux, J.-P., Evrard, A., Cazala, P., Cormier, A., Mameli-Engvall, M., et al. (2005) · Nature

Nicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation

Cited by 566

Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., et al. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 544

Essential roles of enteric neuronal serotonin in gastrointestinal motility and the development/survival of enteric dopaminergic neurons

Li, Z., Chalazonitis, A., Huang, Y.-Y., Mann, J. J., Margolis, K. G., Yang, Q. M., Kim, D. O., Cote, F., Mallet, J., & Gershon, M. D. (2011) · Journal of Neuroscience

Gastrointestinal motility and disordersCongenital gastrointestinal and neural anomalies

Cited by 403

Maternal serotonin is crucial for murine embryonic development

Côté, F., Fligny, C., Bayard, E., Launay, J.-M., Gershon, M. D., Mallet, J., & Vodjdani, G. (2007) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorNeurogenesis and neuroplasticity mechanisms

Cited by 381

Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson disease

Bilang-Bleuel, A., Revah, F., Colin, P., Locquet, I., Robert, J.-J., Mallet, J., & Horellou, P. (1997) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsNerve injury and regeneration

Cited by 297

Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo

Philippe, S., Sarkis, C., Barkats, M., Mammeri, H., Ladroue, C., Petit, C., Mallet, J., & Serguera, C. (2006) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 249

Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

Chéret, C., Gervais, A., Lelli, A., Colin, C., Amar, L., Ravassard, P., Mallet, J., Cumano, A., Krause, K.-H., & Mallat, M. (2008) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsRedox biology and oxidative stress

Cited by 225

Perinatal undernutrition affects the methylation and expression of the leptin gene in adults: implication for the understanding of metabolic syndrome

Jousse, C., Parry, L., Lambert‐Langlais, S., Maurin, A., Averous, J., Bruhat, A., Carraro, V., Tost, J., Letteron, P., Chen, P., et al. (2011) · The FASEB Journal

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 139

Association Between Bipolar Disorder and Monoamine Oxidase A Gene Polymorphisms: Results of a Multicenter Study

Preisig, M., Bellivier, F., Fenton, B. T., Baud, P., Berney, A., Courtet, P., Hardy, P., Golaz, J., Leboyer, M., Mallet, J., et al. (2000) · American Journal of Psychiatry

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 137

A Single Lentivirus Vector Mediates Doxycycline-Regulated Expression of Transgenes in the Brain

Vogel, R., Amar, L., Thi, A. D., Saillour, P., & Mallet, J. (2004) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 68

Hybrid Lentivirus-phiC31-int-NLS Vector Allows Site-Specific Recombination in Murine and Human Cells but Induces DNA Damage

Grandchamp, N., Altémir, D., Philippe, S., Ursulet, S., Pilet, H., Serre, M.-C., Lenain, A., Serguera, C., Mallet, J., & Sarkis, C. (2014) · PLoS ONE

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 11