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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

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Cd8(+) T-Cell Responses to Adeno-Associated Virus Capsid in Humans

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Immunogenicity and toxicity of AAV gene therapy

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The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver

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Circulating CXCR5+PD-1+ Response Predicts Influenza Vaccine Antibody Responses in Young Adults but not Elderly Adults

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Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells

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Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid

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Impact of AAV Capsid-Specific T-Cell Responses on Design and Outcome of Clinical Gene Transfer Trials With Recombinant Adeno-Associated Viral Vectors: An Evolving Controversy

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Novel Vaccines to Human Rabies

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Impact of the Underlying Mutation and the Route of Vector Administration on Immune Responses to Factor IX in Gene Therapy for Hemophilia B

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T Cell-Mediated Immune Responses to AAV and AAV Vectors

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Recombinant Adeno-Associated Virus Vectors Induce Functionally Impaired Transgene Product-Specific CD8+ T Cells in Mice

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Unique Roles of TLR9- and MyD88-Dependent and -Independent Pathways in Adaptive Immune Responses to AAV-Mediated Gene Transfer

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AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes

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Capsid-specific T-cell Responses to Natural Infections With Adeno-associated Viruses in Humans Differ From Those of Nonhuman Primates

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Type I interferon inhibits antibody responses induced by a chimpanzee adenovirus vector.

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The Effect of CpG Sequences on Capsid-Specific CD8+ T Cell Responses to AAV Vector Gene Transfer

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Self-complementary AAVs Induce More Potent Transgene Product-specific Immune Responses Compared to a Single-stranded Genome

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Role of the Vector Genome and Underlying Factor IX Mutation in Immune Responses to AAV Gene Therapy for Hemophilia B

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CD8+ T cell recognition of epitopes within the capsid of adeno-associated virus 8-based gene transfer vectors depends on vectors' genome

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Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged Humans

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Effects of immunosuppression on circulating adeno-associated virus capsid-specific T cells in humans

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