Kroeze, Wesley K.

Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

Roth, B. L., Sheffler, D. J., & Kroeze, W. K. (2004) · Nature Reviews Drug Discovery

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 1,155

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Kroeze, W. K., Sassano, M. F., Huang, X.-P., Lansu, K., McCorvy, J. D., Giguère, P. M., Sciaky, N., & Roth, B. L. (2015) · Nature Structural & Molecular Biology

Receptor Mechanisms and SignalingComputational Drug Discovery Methods

Cited by 755

In silico design of novel probes for the atypical opioid receptor MRGPRX2

Lansu, K., Karpiak, J., Liu, J., Huang, X.-P., McCorvy, J. D., Kroeze, W. K., Che, T., Nagase, H., Carroll, F. I., Jin, J., et al. (2017) · Nature Chemical Biology

Computational Drug Discovery MethodsReceptor Mechanisms and Signaling

Cited by 293

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Huang, X.-P., Karpiak, J., Kroeze, W. K., Zhu, H., Chen, X., Moy, S. S., Saddoris, K. A., Nikolova, V. D., Farrell, M. S., Wang, S., et al. (2015) · Nature

Receptor Mechanisms and SignalingComputational Drug Discovery Methods

Cited by 284

Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily

Roth, B. L., & Kroeze, W. K. (2015) · Journal of Biological Chemistry

Receptor Mechanisms and SignalingComputational Drug Discovery Methods

Cited by 88