Beckers, Johannes

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Doll, S., Proneth, B., Tyurina, Y. Y., Panzilius, E., Kobayashi, S., Ingold, I., Irmler, M., Beckers, J., Aichler, M., Walch, A., et al. (2017) · Nature Chemical Biology

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 4,293

Cardioprotection and lifespan extension by the natural polyamine spermidine

Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., Harger, A., Schipke, J., Zimmermann, A., Schmidt, A., et al. (2016) · Nature Medicine

Polyamine Metabolism and ApplicationsGenetics, Aging, and Longevity in Model Organisms

Cited by 1,168

Rapamycin extends murine lifespan but has limited effects on aging

Neff, F., Flores-Dominguez, D., Ryan, D. P., Horsch, M., Schröder, S., Adler, T., Afonso, L. C., Aguilar-Pimentel, J. A., Becker, L., Garrett, L., et al. (2013) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 374

Epigenetic germline inheritance of diet-induced obesity and insulin resistance

Huypens, P., Sass, S., Wu, M., Dyckhoff, D., Tschöp, M., Theis, F., Marschall, S., de Angelis, M. H., & Beckers, J. (2016) · Nature Genetics

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 366

In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells

Beckervordersandforth, R., Tripathi, P., Ninkovic, J., Bayam, E., Lepier, A., Stempfhuber, B., Kirchhoff, F., Hirrlinger, J., Haslinger, A., Lie, D. C., et al. (2010) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 335

Prevalence of sexual dimorphism in mammalian phenotypic traits

Karp, N. A., Mason, J., Beaudet, A. L., Benjamini, Y., Bower, L., Braun, R. E., Brown, S. D. M., Chesler, E. J., Dickinson, M. E., Flenniken, A. M., et al. (2017) · Nature Communications

Sex and Gender in HealthcareGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Cited by 257

Astrocyte reactivity after brain injury—: The role of galectins 1 and 3

Sirko, S., Irmler, M., Gascón, S., Bek, S., Schneider, S., Dimou, L., Obermann, J., De Souza Paiva, D., Poirier, F., Beckers, J., et al. (2015) · Glia

Neurogenesis and neuroplasticity mechanismsGalectins and Cancer Biology

Cited by 126

Cytokine response of primary human myotubes in an in vitro exercise model

Scheler, M., Irmler, M., Lehr, S., Hartwig, S., Staiger, H., Al-Hasani, H., Beckers, J., Hrabé de Angelis, M., Häring, H.-U., & Weigert, C. (2013) · American Journal of Physiology-Cell Physiology

Exercise and Physiological ResponsesMuscle Physiology and Disorders

Cited by 123

Generation of pancreatic β cells from CD177+ anterior definitive endoderm

Mahaddalkar, P. U., Scheibner, K., Pfluger, S., Ansarullah, Sterr, M., Beckenbauer, J., Irmler, M., Beckers, J., Knöbel, S., & Lickert, H. (2020) · Nature Biotechnology

Pluripotent Stem Cells ResearchPancreatic function and diabetes

Cited by 115

AP2γ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex

Pinto, L., Drechsel, D., Schmid, M.-T., Ninkovic, J., Irmler, M., Brill, M. S., Restani, L., Gianfranceschi, L., Cerri, C., Weber, S. N., et al. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 100

Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

Berti, L., Irmler, M., Zdichavsky, M., Meile, T., Böhm, A., Stefan, N., Fritsche, A., Beckers, J., Königsrainer, A., Häring, H.-U., et al. (2015) · Molecular Metabolism

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 73

Differential and Converging Molecular Mechanisms of Antidepressants’ Action in the Hippocampal Dentate Gyrus

Patrício, P., Mateus-Pinheiro, A., Irmler, M., Alves, N. D., Machado-Santos, A. R., Morais, M., Correia, J. S., Korostynski, M., Piechota, M., Stoffel, R., et al. (2015) · Neuropsychopharmacology

Treatment of Major DepressionStress Responses and Cortisol

Cited by 57

HoxGene Expression in Limbs: Colinearity by Opposite Regulatory Controls

Hérault, Y., Beckers, J., Gérard, M., & Duboule, D. (1999) · Developmental Biology

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 56

Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-induced diabetic mice

Franko, A., Huypens, P., Neschen, S., Irmler, M., Rozman, J., Rathkolb, B., Neff, F., Prehn, C., Dubois, G., Baumann, M., et al. (2016) · Diabetes

Peroxisome Proliferator-Activated ReceptorsDiabetes Treatment and Management

Cited by 42

Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex

Hérault, Y., Beckers, J., Kondo, T., Fraudeau, N., & Duboule, D. (1998) · Development

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 35

CIP2A promotes T-cell activation and immune response to Listeria monocytogenes infection

Côme, C., Cvrljevic, A., Khan, M. M., Treise, I., Adler, T., Aguilar-Pimentel, J. A., Au-Yeung, B., Sittig, E., Laajala, T. D., Chen, Y., et al. (2016) · PLoS ONE

T-cell and B-cell ImmunologySignaling Pathways in Disease

Cited by 20