Brüning, Jens C.
University of Cologne · Max Planck Institute for Metabolism Research · Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · University Hospital Cologne · German Center for Diabetes Research
35 papers on CoChatORCID 0000-0002-6619-0092
Most cited papers
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Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity
Garinis, G. A., Uittenboogaard, L. M., Stachelscheid, H., Fousteri, M., van Ijcken, W., Breit, T. M., van Steeg, H., Mullenders, L. H. F., van der Horst, G. T. J., Brüning, J. C., et al. (2009) · Nature Cell Biology
Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence
Cited by 138
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PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding
Jais, A., Paeger, L., Sotelo-Hitschfeld, T., Bremser, S., Prinzensteiner, M., Klemm, P., Mykytiuk, V., Widdershooven, P. J. M., Vesting, A. J., Grzelka, K., et al. (2020) · Neuron
Regulation of Appetite and ObesityHypothalamic control of reproductive hormones
Cited by 129
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Activation of Stat3 Signaling in AgRP Neurons Promotes Locomotor Activity
Mesaros, A., Koralov, S. B., Rother, E., Wunderlich, F. T., Ernst, M. B., Barsh, G. S., Rajewsky, K., & Brüning, J. C. (2008) · Cell Metabolism
Regulation of Appetite and ObesityHypothalamic control of reproductive hormones
Cited by 128
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Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1
Whitham, M., Chan, M. H. S., Pal, M., Matthews, V. B., Prelovsek, O., Lunke, S., El-Osta, A., Broenneke, H., Alber, J., Brüning, J. C., et al. (2012) · Journal of Biological Chemistry
Exercise and Physiological ResponsesMuscle Physiology and Disorders
Cited by 107
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Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic β cells recapitulates neonatal diabetes
Girard, C. A., Wunderlich, F. T., Shimomura, K., Collins, S., Kaizik, S., Proks, P., Abdulkader, F., Clark, A., Ball, V., Zubcevic, L., et al. (2008) · Journal of Clinical Investigation
Pancreatic function and diabetesIon channel regulation and function
Cited by 105
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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding
Dodd, G. T., Andrews, Z. B., Simonds, S. E., Michael, N. J., DeVeer, M., Brüning, J. C., Spanswick, D., Cowley, M. A., & Tiganis, T. (2017) · Cell Metabolism
Regulation of Appetite and ObesityAdipose Tissue and Metabolism
Cited by 66
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Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin
Paeger, L., Karakasilioti, I., Altmüller, J., Frommolt, P., Brüning, J., & Kloppenburg, P. (2017) · eLife
Regulation of Appetite and ObesityHypothalamic control of reproductive hormones
Cited by 57
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Modulation of midbrain neurocircuitry by intranasal insulin
Edwin Thanarajah, S., Iglesias, S., Kuzmanovic, B., Rigoux, L., Stephan, K. E., Brüning, J. C., & Tittgemeyer, M. (2019) · NeuroImage
Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies
Cited by 55
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Liraglutide restores impaired associative learning in individuals with obesity
Hanssen, R., Rigoux, L., Kuzmanovic, B., Iglesias, S., Kretschmer, A. C., Schlamann, M., Albus, K., Edwin Thanarajah, S., Sitnikow, T., Melzer, C., et al. (2023) · Nature Metabolism
Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior
Cited by 52
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The role of insulin sensitivity and intranasally applied insulin on olfactory perception
Edwin Thanarajah, S., Hoffstall, V., Rigoux, L., Hanssen, R., Brüning, J. C., & Tittgemeyer, M. (2019) · Scientific Reports
Olfactory and Sensory Function StudiesBiochemical Analysis and Sensing Techniques
Cited by 46
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Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma
Mittenbühler, M. J., Sprenger, H.-G., Gruber, S., Wunderlich, C. M., Kern, L., Brüning, J. C., & Wunderlich, F. T. (2018) · Molecular Metabolism
Cytokine Signaling Pathways and InteractionsAdipokines, Inflammation, and Metabolic Diseases
Cited by 18
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