Kleinschmidt, Jürgen A.

Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2

Girod, A., Ried, M., Wobus, C., Lahm, H., Leike, K., Kleinschmidt, J., Deléage, G., & Hallek, M. (1999) · Nature Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 405

A viral assembly factor promotes AAV2 capsid formation in the nucleolus

Sonntag, F., Schmidt, K., & Kleinschmidt, J. A. (2010) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchBacteriophages and microbial interactions

Cited by 392

Identification of a heparin-binding motif on adeno-associated virus type 2 capsids

Kern, A., Schmidt, K., Leder, C., Müller, O. J., Wobus, C. E., Bettinger, K., Von der Lieth, C. W., King, J. A., & Kleinschmidt, J. A. (2003) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 380

The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivity

Girod, A., Wobus, C. E., Zádori, Z., Ried, M., Leike, K., Tijssen, P., Kleinschmidt, J. A., & Hallek, M. (2002) · Journal of General Virology

Virus-based gene therapy researchParvovirus B19 Infection Studies

Cited by 354

Subcellular compartmentalization of adeno-associated virus type 2 assembly

Wistuba, A., Kern, A., Weger, S., Grimm, D., & Kleinschmidt, J. A. (1997) · Journal of Virology

Virus-based gene therapy researchParvovirus B19 Infection Studies

Cited by 219

AAV Capsid Structure and Cell Interactions

Agbandje-McKenna, M., & Kleinschmidt, J. (2012) · Methods in Molecular Biology

Virus-based gene therapy researchParvovirus B19 Infection Studies

Cited by 215

Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2

Grimm, D., Kern, A., Pawlita, M., Ferrari, F. K., Samulski, R. J., & Kleinschmidt, J. A. (1999) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 195

The Assembly-Activating Protein Promotes Capsid Assembly of Different Adeno-Associated Virus Serotypes

Sonntag, F., Köther, K., Schmidt, K., Weghofer, M., Raupp, C., Nieto, K., Kuck, A., Gerlach, B., Böttcher, B., Müller, O. J., et al. (2011) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 184

Electron cryo‐microscopy and image reconstruction of adeno‐associated virus type 2 empty capsids

Kronenberg, S., Kleinschmidt, J. A., & Böttcher, B. (2001) · The EMBO Reports

Advanced Electron Microscopy Techniques and ApplicationsVirus-based gene therapy research

Cited by 161

Intermediates of adeno-associated virus type 2 assembly: identification of soluble complexes containing Rep and Cap proteins

Wistuba, A., Weger, S., Kern, A., & Kleinschmidt, J. A. (1995) · Journal of Virology

Virus-based gene therapy researchParvovirus B19 Infection Studies

Cited by 147

Assembly of viruslike particles by recombinant structural proteins of adeno-associated virus type 2 in insect cells

Ruffing, M., Zentgraf, H., & Kleinschmidt, J. A. (1992) · Journal of Virology

Viral Infectious Diseases and Gene Expression in InsectsVirus-based gene therapy research

Cited by 109

Impact of VP1-Specific Protein Sequence Motifs on Adeno-Associated Virus Type 2 Intracellular Trafficking and Nuclear Entry

Popa-Wagner, R., Porwal, M., Kann, M., Reuss, M., Weimer, M., Florin, L., & Kleinschmidt, J. A. (2012) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 109

Properties of the Adeno-Associated Virus Assembly-Activating Protein

Naumer, M., Sonntag, F., Schmidt, K., Nieto, K., Panke, C., Davey, N. E., Popa-Wagner, R., & Kleinschmidt, J. A. (2012) · Journal of Virology

Virus-based gene therapy researchBacteriophages and microbial interactions

Cited by 97

Focal Delivery of AAV2/1-transgenes Into the Rat Brain by Localized Ultrasound-induced BBB Opening

Alonso, A., Reinz, E., Leuchs, B., Kleinschmidt, J., Fatar, M., Geers, B., Lentacker, I., Hennerici, M. G., de Smedt, S. C., & Meairs, S. (2013) · Molecular Therapy - Nucleic Acids

Ultrasound and Hyperthermia ApplicationsBarrier Structure and Function Studies

Cited by 93

Development of AAV serotype-specific ELISAs using novel monoclonal antibodies

Kuck, D., Kern, A., & Kleinschmidt, J. A. (2007) · Journal of Virological Methods

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 74

Intranasal Vaccination with AAV5 and 9 Vectors Against Human Papillomavirus Type 16 in Rhesus Macaques

Nieto, K., Stahl-Hennig, C., Leuchs, B., Müller, M., Gissmann, L., & Kleinschmidt, J. A. (2012) · Human Gene Therapy

Virus-based gene therapy researchCervical Cancer and HPV Research

Cited by 46

Nuclear translocation of adeno-associated virus type 2 capsid proteins for virion assembly

Popa-Wagner, R., Sonntag, F., Schmidt, K., King, J., & Kleinschmidt, J. A. (2012) · Journal of General Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 24