Kitteringham, Neil R.

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Bell, C. C., Hendriks, D. F. G., Moro, S. M. L., Ellis, E., Walsh, J., Renblom, A., Fredriksson Puigvert, L., Dankers, A. C. A., Jacobs, F., Snoeys, J., et al. (2016) · Scientific Reports

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 739

Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

Park, B. K., Pirmohamed, M., & Kitteringham, N. R. (1998) · Chemical Research in Toxicology

Drug-Induced Adverse ReactionsPharmacogenetics and Drug Metabolism

Cited by 267

Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway

Copple, I. M., Lister, A., Obeng, A. D., Kitteringham, N. R., Jenkins, R. E., Layfield, R., Foster, B. J., Goldring, C. E., & Park, B. K. (2010) · Journal of Biological Chemistry

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 260

Assessing the Safety of Stem Cell Therapeutics

Goldring, C. E. P., Duffy, P. A., Benvenisty, N., Andrews, P. W., Ben-David, U., Eakins, R., French, N., Hanley, N. A., Kelly, L., Kitteringham, N. R., et al. (2011) · Cell Stem Cell

Biomedical Ethics and RegulationPluripotent Stem Cells Research

Cited by 245

Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—Implications for therapeutic targeting of Nrf2

Olayanju, A., Copple, I. M., Bryan, H. K., Edge, G. T., Sison, R. L., Wong, M. W., Lai, Z.-Q., Lin, Z.-X., Dunn, K., Sanderson, C. M., et al. (2015) · Free Radical Biology and Medicine

Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents

Cited by 232

High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

Antoine, D. J., Williams, D. P., Kipar, A., Jenkins, R. E., Regan, S. L., Sathish, J. G., Kitteringham, N. R., & Park, B. K. (2009) · Toxicological Sciences

Drug-Induced Hepatotoxicity and ProtectionCell death mechanisms and regulation

Cited by 223

Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

Heslop, J. A., Rowe, C., Walsh, J., Sison-Young, R., Jenkins, R., Kamalian, L., Kia, R., Hay, D., Jones, R. P., Malik, H. Z., et al. (2017) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 141

Proteome-Wide Analyses of Human Hepatocytes During Differentiation and Dedifferentiation

Rowe, C., Gerrard, D. T., Jenkins, R., Berry, A., Durkin, K., Sundstrom, L., Goldring, C. E., Park, K. B., Kitteringham, N. R., Hanley, K. P., et al. (2013) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 133

Network Analysis of Primary Hepatocyte Dedifferentiation Using a Shotgun Proteomics Approach

Rowe, C., Goldring, C. E. P., Kitteringham, N. R., Jenkins, R. E., Lane, B. S., Sanderson, C., Elliott, V., Platt, V., Metcalfe, P., & Park, B. K. (2010) · Journal of Proteome Research

Liver physiology and pathologyAdvanced Proteomics Techniques and Applications

Cited by 51

The effect of genetic polymorphisms in CYP2C9 on sulphamethoxazole N-hydroxylation

Gill, H. J., Tjia, J. F., Kitteringham, N. R., Pirmohamed, M., Back, D. J., & Park, B. K. (1999) · Pharmacogenetics

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection

Cited by 48

Confounding Effect of Obstructive Jaundice in the Interpretation of Proteomic Plasma Profiling Data for Pancreatic Cancer

Yan, L., Tonack, S., Smith, R., Dodd, S., Jenkins, R. E., Kitteringham, N., Greenhalf, W., Ghaneh, P., Neoptolemos, J. P., & Costello, E. (2009) · Journal of Proteome Research

Pancreatic and Hepatic Oncology ResearchAdvanced Proteomics Techniques and Applications

Cited by 44