Murphy, Leon O.
13 papers on CoChat
Most cited papers
- Verified
Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 3,996
- Verified
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
Düvel, K., Yecies, J. L., Menon, S., Raman, P., Lipovsky, A. I., Souza, A. L., Triantafellow, E., Ma, Q., Gorski, R., Cleaver, S., et al. (2010) · Molecular Cell
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 2,020
- Verified
Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
Nicklin, P., Bergman, P., Zhang, B., Triantafellow, E., Wang, H., Nyfeler, B., Yang, H., Hild, M., Kung, C., Wilson, C., et al. (2009) · Cell
Amino Acid Enzymes and MetabolismPI3K/AKT/mTOR signaling in cancer
Cited by 1,798
- Verified
Molecular definitions of autophagy and related processes
Galluzzi, L., Baehrecke, E. H., Ballabio, A., Boya, P., Bravo‐San Pedro, J. M., Cecconi, F., Choi, A. M., Chu, C. T., Codogno, P., Colombo, M. I., et al. (2017) · The EMBO Journal
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 1,646
- Verified
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
Maira, S.-M., Stauffer, F., Brueggen, J., Furet, P., Schnell, C., Fritsch, C., Brachmann, S., Chène, P., De Pover, A., Schoemaker, K., et al. (2008) · Molecular Cancer Therapeutics
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 1,134
- Verified
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
Dowdle, W. E., Nyfeler, B., Nagel, J., Elling, R. A., Liu, S., Triantafellow, E., Menon, S., Wang, Z., Honda, A., Pardee, G., et al. (2014) · Nature Cell Biology
Autophagy in Disease and TherapyIron Metabolism and Disorders
Cited by 759
- Verified
Mapk signal specificity: The right place at the right time
Murphy, L. O., & Blenis, J. (2006) · Trends in Biochemical Sciences
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 707
- Verified
The E3 Ligase MuRF1 Degrades Myosin Heavy Chain Protein in Dexamethasone-Treated Skeletal Muscle
Clarke, B. A., Drujan, D., Willis, M. S., Murphy, L. O., Corpina, R. A., Burova, E., Rakhilin, S. V., Stitt, T. N., Patterson, C., Latres, E., et al. (2007) · Cell Metabolism
Muscle Physiology and DisordersUbiquitin and proteasome pathways
Cited by 683
- Verified
TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
Dibble, C. C., Elis, W., Menon, S., Qin, W., Klekota, J., Asara, J. M., Finan, P. M., Kwiatkowski, D. J., Murphy, L. O., & Manning, B. D. (2012) · Molecular Cell
PI3K/AKT/mTOR signaling in cancerTuberous Sclerosis Complex Research
Cited by 612
- Verified
Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling
d’Hennezel, E., Abubucker, S., Murphy, L. O., & Cullen, T. W. (2017) · mSystems
Immune Response and InflammationGut microbiota and health
Cited by 324
- Verified
Spatially Separate Docking Sites on ERK2 Regulate Distinct Signaling Events In Vivo
Dimitri, C. A., Dowdle, W., MacKeigan, J. P., Blenis, J., & Murphy, L. O. (2005) · Current Biology
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 114
- Verified
Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice
Fetalvero, K. M., Yu, Y., Goetschkes, M., Liang, G., Valdez, R. A., Gould, T., Triantafellow, E., Bergling, S., Loureiro, J., Eash, J., et al. (2013) · Molecular and Cellular Biology
Autophagy in Disease and TherapyMuscle Physiology and Disorders
Cited by 96
- Verified
Relieving Autophagy and 4EBP1 from Rapamycin Resistance
Nyfeler, B., Bergman, P., Triantafellow, E., Wilson, C. J., Zhu, Y., Radetich, B., Finan, P. M., Klionsky, D. J., & Murphy, L. O. (2011) · Molecular and Cellular Biology
PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy
Cited by 94
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