Krainer, Adrian R.

Listening to silence and understanding nonsense: exonic mutations that affect splicing

Cartegni, L., Chew, S. L., & Krainer, A. R. (2002) · Nature Reviews Genetics

RNA Research and SplicingRNA regulation and disease

Cited by 2,209

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

Kole, R., Krainer, A. R., & Altman, S. (2012) · Nature Reviews Drug Discovery

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 1,152

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

Guo, Y., Xu, Q., Canzio, D., Shou, J., Li, J., Gorkin, D. U., Jung, I., Wu, H., Zhai, Y., Tang, Y., et al. (2015) · Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 958

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

Clower, C. V., Chatterjee, D., Wang, Z., Cantley, L. C., Vander Heiden, M. G., & Krainer, A. R. (2010) · Proceedings of the National Academy of Sciences

RNA Research and SplicingCancer, Hypoxia, and Metabolism

Cited by 424

Antisense Oligonucleotide Therapies for Neurodegenerative Diseases

Bennett, C. F., Krainer, A. R., & Cleveland, D. W. (2019) · Annual Review of Neuroscience

RNA Interference and Gene DeliveryNeurogenetic and Muscular Disorders Research

Cited by 353

Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

Wang, E., Lu, S. X., Pastore, A., Chen, X., Imig, J., Chun-Wei Lee, S., Hockemeyer, K., Ghebrechristos, Y. E., Yoshimi, A., Inoue, D., et al. (2019) · Cancer Cell

RNA Research and SplicingAcute Myeloid Leukemia Research

Cited by 338

HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism

Weyn-Vanhentenryck, S. M., Mele, A., Yan, Q., Sun, S., Farny, N., Zhang, Z., Xue, C., Herre, M., Silver, P. A., Zhang, M. Q., et al. (2014) · Cell Reports

RNA Research and SplicingGenetics and Neurodevelopmental Disorders

Cited by 333

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2

Zhang, C., Zhang, Z., Castle, J., Sun, S., Johnson, J., Krainer, A. R., & Zhang, M. Q. (2008) · Genes & Development

RNA Research and SplicingRNA regulation and disease

Cited by 300

Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates

Rigo, F., Chun, S. J., Norris, D. A., Hung, G., Lee, S., Matson, J., Fey, R. A., Gaus, H., Hua, Y., Grundy, J. S., et al. (2014) · The Journal of Pharmacology and Experimental Therapeutics

Neurogenetic and Muscular Disorders ResearchRNA Interference and Gene Delivery

Cited by 283

Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein

Jiang, J., Zhang, Y., Krainer, A. R., & Xu, R.-M. (1999) · Proceedings of the National Academy of Sciences

Enzyme Structure and FunctionMitochondrial Function and Pathology

Cited by 253

OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds

Wu, J., Anczuków, O., Krainer, A. R., Zhang, M. Q., & Zhang, C. (2013) · Nucleic Acids Research

Genomics and Phylogenetic StudiesRNA Research and Splicing

Cited by 123