Hegardt, Fausto G.

Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor

Mascaró, C., Acosta, E., Ortiz, J. A., Marrero, P. F., Hegardt, F. G., & Haro, D. (1998) · Journal of Biological Chemistry

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Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control

Noland, R. C., Koves, T. R., Seiler, S. E., Lum, H., Lust, R. M., Ilkayeva, O., Stevens, R. D., Hegardt, F. G., & Muoio, D. M. (2009) · Journal of Biological Chemistry

Metabolism and Genetic DisordersAdipose Tissue and Metabolism

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Molecular Therapy for Obesity and Diabetes Based on a Long-Term Increase in Hepatic Fatty-Acid Oxidation §Δ

Orellana-Gavaldà, J. M., Herrero, L., Malandrino, M. I., Pañeda, A., Sol Rodríguez-Peña, M., Petry, H., Asins, G., Van Deventer, S., Hegardt, F. G., & Serra, D. (2011) · Hepatology

Adipose Tissue and MetabolismVirus-based gene therapy research

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CPT I overexpression protects L6E9 muscle cells from fatty acid-induced insulin resistance

Sebastián, D., Herrero, L., Serra, D., Asins, G., & Hegardt, F. G. (2007) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

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Novel Effect of C75 on Carnitine Palmitoyltransferase I Activity and Palmitate Oxidation

Bentebibel, A., Sebastián, D., Herrero, L., López-Viñas, E., Serra, D., Asins, G., Gómez-Puertas, P., & Hegardt, F. G. (2006) · Biochemistry

Cancer, Lipids, and MetabolismPeroxisome Proliferator-Activated Receptors

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C75 is converted to C75-CoA in the hypothalamus, where it inhibits carnitine palmitoyltransferase 1 and decreases food intake and body weight

Mera, P., Bentebibel, A., López-Viñas, E., Cordente, A. G., Gurunathan, C., Sebastián, D., Vázquez, I., Herrero, L., Ariza, X., Gómez-Puertas, P., et al. (2009) · Biochemical Pharmacology

Regulation of Appetite and ObesityPeroxisome Proliferator-Activated Receptors

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Redesign of carnitine acetyltransferase specificity by protein engineering

Cordente, A. G., López-Viñas, E., Vázquez, M. I., Swiegers, J. H., Pretorius, I. S., Gómez-Puertas, P., Hegardt, F. G., Asins, G., & Serra, D. (2004) · Journal of Biological Chemistry

Protein Structure and DynamicsEnzyme Structure and Function

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