Monk, Brian C.

Efflux-Mediated Antifungal Drug Resistance

Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Baret, P. V., Keniya, M. V., Tanabe, K., Niimi, M., Goffeau, A., & Monk, B. C. (2009) · Clinical Microbiology Reviews

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 608

Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase

Sagatova, A. A., Keniya, M. V., Wilson, R. K., Monk, B. C., & Tyndall, J. D. A. (2015) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal Plant Pathogen Control

Cited by 210

Candida albicans drug resistance—Another way to cope with stress

Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Tanabe, K., Niimi, M., & Monk, B. C. (2007) · Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 208

Targeting Efflux Pumps to Overcome Antifungal Drug Resistance

Holmes, A. R., Cardno, T. S., Strouse, J. J., Ivnitski-Steele, I., Keniya, M. V., Lackovic, K., Monk, B. C., Sklar, L. A., & Cannon, R. D. (2016) · Future Medicinal Chemistry

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 156

Overexpression of Candida albicans CDR1,CDR2, or MDR1 Does Not Produce Significant Changes in Echinocandin Susceptibility

Niimi, K., Maki, K., Ikeda, F., Holmes, A. R., Lamping, E., Niimi, M., Monk, B. C., & Cannon, R. D. (2006) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 134

Crystal structures of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provide tools for antifungal discovery

Keniya, M. V., Sabherwal, M., Wilson, R. K., Woods, M. A., Sagatova, A. A., Tyndall, J. D. A., & Monk, B. C. (2018) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityEnzyme Structure and Function

Cited by 115

The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates

Holmes, A. R., Keniya, M. V., Ivnitski-Steele, I., Monk, B. C., Lamping, E., Sklar, L. A., & Cannon, R. D. (2012) · Antimicrobial Agents and Chemotherapy

Antifungal resistance and susceptibilityDrug Transport and Resistance Mechanisms

Cited by 106

Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2

Holmes, A. R., Tsao, S., Ong, S., Lamping, E., Niimi, K., Monk, B. C., Niimi, M., Kaneko, A., Holland, B. R., Schmid, J., et al. (2006) · Molecular Microbiology

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 68

Phosphorylation of Candida glabrata ATP-binding Cassette Transporter Cdr1p Regulates Drug Efflux Activity and ATPase Stability

Wada, S.-I., Tanabe, K., Yamazaki, A., Niimi, M., Uehara, Y., Niimi, K., Lamping, E., Cannon, R. D., & Monk, B. C. (2005) · Journal of Biological Chemistry

Drug Transport and Resistance MechanismsAntifungal resistance and susceptibility

Cited by 39