Cited by 211Antifungal resistance and susceptibilityFungal and yeast genetics researchFungal Plant Pathogen Control

Candida albicans drug resistance—Another way to cope with stress

Cannon, Richard D., Lamping, Erwin, Holmes, Ann R., Niimi, Kyoko, Tanabe, Koichi, Niimi, Masakazu, Monk, Brian C.·2007·Microbiology

Abstract

There are relatively few classes of antifungal drugs. This restricts clinicians' therapeutic choices and these choices are further reduced by the emergence of drug resistance. Exposure to antifungal drugs represents an environmental stress for the fungal pathogen Candida albicans. The immediate response of C. albicans to antifungals may be drug tolerance, which can lead to drug resistance. This article examines C. albicans drug resistance from the perspective of it being a stress response and investigates how commonality with other stress-response pathways gives insights into the prospects for overcoming, or preventing, drug resistance.

Integrity signals

Registry

Crossref · 10.1099/mic.0.2007/010405-0

Cites

46 of 46 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Iron limitation increases the susceptibility of dispersed daughter cells from biofilms to amphotericin B.

    “However, iron limitation increased the susceptibility of dispersed daughter cells from biofilms to amphotericin B, detected by a number of cells which induce responses by signalling pathways [162].”

    From Candida glabrata Biofilms: How Far Have We Come? (2017) · cites this paper as [162]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Cannon, R. D., Lamping, E., Holmes, A. R., Niimi, K., Tanabe, K., Niimi, M., & Monk, B. C.
Affiliations
  • University of Otago (NZ)
  • National Institute of Infectious Diseases (JP)
Venue
Microbiology
Published
2007-10-01
Volume
153
Issue
10
Pages
3211-3217
ISSN
  • 1350-0872 (ISSN-L)
  • 1465-2080
OpenAlex
W2093997770
Cited by
208
References
46
Citations by year
2026: 2 · 2025: 2 · 2024: 4 · 2023: 9 · 2022: 3 · 2021: 17 · 2020: 10 · 2019: 16 · 2018: 13 · 2017: 15 · 2016: 13 · 2015: 9 · 2014: 19 · 2013: 19 · 2012: 10
FWCI
1.34
Type
journal article
Language
en
Open access
closed
Locations
  • Microbiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Japan Health Sciences Foundation
  • National Institutes of Health
  • National Institute of Dental and Craniofacial Research (R01DE016885)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Fungal Plant Pathogen Control
Keywords
Candida albicans, antifungal resistance, drug tolerance, stress response, environmental stress, antifungal agents, stress response pathways, fungal pathogens
MeSH terms
Animals, Antifungal Agents, Candida albicans, Candidiasis, Humans, Drug Resistance, Fungal

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review