Most cited biochemistry, genetics and molecular biology papers
- Verified
Senescence, apoptosis and therapy — cutting the lifelines of cancer
Schmitt, C. A. (2003) · Nature Reviews Cancer
Telomeres, Telomerase, and SenescenceCell death mechanisms and regulation
Cited by 295
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AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy
Astle, M. V., Hannan, K. M., Ng, P. Y., Lee, R. S., George, A. J., Hsu, A. K., Haupt, Y., Hannan, R. D., & Pearson, R. B. (2012) · Oncogene
Telomeres, Telomerase, and SenescencePI3K/AKT/mTOR signaling in cancer
Cited by 295
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Probing the kinesin reaction cycle with a 2D optical force clamp
Block, S. M., Asbury, C. L., Shaevitz, J. W., & Lang, M. J. (2003) · Proceedings of the National Academy of Sciences
Microtubule and mitosis dynamicsForce Microscopy Techniques and Applications
Cited by 295
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Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila
Igaki, T., Pastor-Pareja, J. C., Aonuma, H., Miura, M., & Xu, T. (2009) · Developmental Cell
Cell death mechanisms and regulationCellular transport and secretion
Cited by 295
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A Mechanism for Translationally Coupled mRNA Turnover
Grosset, C., Chen, C.-Y. A., Xu, N., Sonenberg, N., Jacquemin-Sablon, H., & Shyu, A.-B. (2000) · Cell
RNA Research and SplicingRNA and protein synthesis mechanisms
Cited by 295
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Mitochondrial complex ii: At the crossroads
Bezawork-Geleta, A., Rohlena, J., Dong, L., Pacak, K., & Neuzil, J. (2017) · Trends in Biochemical Sciences
Mitochondrial Function and PathologyMetabolism and Genetic Disorders
Cited by 295
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Cancer and aging: a model for the cancer promoting effects of the aging stroma
Krtolica, A., & Campisi, J. (2002) · The International Journal of Biochemistry & Cell Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 295
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Cloning and Characterization of GEF-H1, a Microtubule-associated Guanine Nucleotide Exchange Factor for Rac and Rho GTPases
Ren, Y., Li, R., Zheng, Y., & Busch, H. (1998) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingCellular transport and secretion
Cited by 295
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Ultrastructural Maturation of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Long-Term Culture
Kamakura, T., Makiyama, T., Sasaki, K., Yoshida, Y., Wuriyanghai, Y., Chen, J., Hattori, T., Ohno, S., Kita, T., Horie, M., et al. (2013) · Circulation Journal
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 295
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Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury
Saeedi, B. J., Liu, K. H., Owens, J. A., Hunter-Chang, S., Camacho, M. C., Eboka, R. U., Chandrasekharan, B., Baker, N. F., Darby, T. M., Robinson, B. S., et al. (2020) · Cell Metabolism
Genomics, phytochemicals, and oxidative stressGut microbiota and health
Cited by 295
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Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells
Várnai, P., Rother, K. I., & Balla, T. (1999) · Journal of Biological Chemistry
Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer
Cited by 295
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Refinement of Protein Structures into Low-Resolution Density Maps Using Rosetta
DiMaio, F., Tyka, M. D., Baker, M. L., Chiu, W., & Baker, D. (2009) · Journal of Molecular Biology
Advanced Electron Microscopy Techniques and ApplicationsProtein Structure and Dynamics
Cited by 295
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Caffeine inhibits the checkpoint kinase ATM
Blasina, A., Price, B. D., Turenne, G. A., & McGowan, C. H. (1999) · Current Biology
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 295
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Isolated Hepatocyte Transplantation in an Infant With a Severe Urea Cycle Disorder
Horslen, S. P., McCowan, T. C., Goertzen, T. C., Warkentin, P. I., Cai, H. B., Strom, S. C., & Fox, I. J. (2003) · Pediatrics
Metabolism and Genetic DisordersOrgan Transplantation Techniques and Outcomes
Cited by 295
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Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3
Lee, J. H., Budanov, A. V., Talukdar, S., Park, E. J., Park, H. L., Park, H.-W., Bandyopadhyay, G., Li, N., Aghajan, M., Jang, I., et al. (2012) · Cell Metabolism
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 295
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Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
Enders, A., Bouillet, P., Puthalakath, H., Xu, Y., Tarlinton, D. M., & Strasser, A. (2003) · The Journal of Experimental Medicine
Cell death mechanisms and regulationT-cell and B-cell Immunology
Cited by 295
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DNA end-joining catalyzed by human cell-free extracts
Baumann, P., & West, S. C. (1998) · Proceedings of the National Academy of Sciences
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 295
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AAV-1–mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells
Mingozzi, F., Meulenberg, J. J., Hui, D. J., Basner-Tschakarjan, E., Hasbrouck, N. C., Edmonson, S. A., Hutnick, N. A., Betts, M. R., Kastelein, J. J., Stroes, E. S., et al. (2009) · Blood
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 295
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Inhibition of translation in eukaryotic systems by harringtonine
FRESNO, M., JIMÉNEZ, A., & VÁZQUEZ, D. (1977) · European Journal of Biochemistry
RNA and protein synthesis mechanismsToxin Mechanisms and Immunotoxins
Cited by 295
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A non-negative matrix factorization method for detecting modules in heterogeneous omics multi-modal data
Yang, Z., & Michailidis, G. (2016) · Bioinformatics
Gene expression and cancer classificationBioinformatics and Genomic Networks
Cited by 295
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Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
Özcan, S., Alessio, N., Acar, M. B., Mert, E., Omerli, F., Peluso, G., & Galderisi, U. (2016) · Aging
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 295
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Prions and their partners in crime
Caughey, B., & Baron, G. S. (2006) · Nature
Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments
Cited by 295
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Recombination initiation maps of individual human genomes
Pratto, F., Brick, K., Khil, P., Smagulova, F., Petukhova, G. V., & Camerini-Otero, R. D. (2014) · Science
DNA Repair MechanismsChromosomal and Genetic Variations
Cited by 295
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Mutant KRAS is a druggable target for pancreatic cancer
Zorde Khvalevsky, E., Gabai, R., Rachmut, I. H., Horwitz, E., Brunschwig, Z., Orbach, A., Shemi, A., Golan, T., Domb, A. J., Yavin, E., et al. (2013) · Proceedings of the National Academy of Sciences
RNA Interference and Gene DeliveryPancreatic and Hepatic Oncology Research
Cited by 295
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