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A New Formula for Depigmenting Human Skin
Abstract
Complete depigmentation of the noraml skin of adult male blacks was procured by the daily application for five to seven weeks of a formula consisting of 0.1% tretinoin, 5.0% hydroquinone, 0.1% dexamethasone, and hydrophilic ointment. Depigmentation was not attainable when any one of the components was omitted. The formula was therapeutically effective in treatment of melasma, ephelides, and postinflammatory hyperpigmentation. Senile lentigines were resistant to this therapy.
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Citations
Cited by
Melanin pigmentation in mammalian skin and its hormonal regulation
Slominski, A., Tobin, D. J., Shibahara, S., & Wortsman, J. (2004) · Physiological Reviews · doi:10.1152/physrev.00044.2003 · Cited by 2,015
Chemical and Instrumental Approaches to Treat Hyperpigmentation
Briganti, S., Camera, E., & Picardo, M. (2003) · Pigment Cell Research · doi:10.1034/j.1600-0749.2003.00029.x · Cited by 837
Topical tretinoin for photoaged skin
Kligman, A. M., Grove, G. L., Hirose, R., & Leyden, J. J. (1986) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(86)70242-9 · Cited by 620
Self-citationDel Bino, S., Duval, C., & Bernerd, F. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092668 · Cited by 315
Ethnic skin disorders overview
Halder, R. M., & Nootheti, P. K. (2003) · Journal of the American Academy of Dermatology · doi:10.1067/mjd.2003.274 · Cited by 240
Metadata
- Authors
- Kligman, A. M.
- Venue
- Archives of Dermatology
- Publisher
- American Medical Association
- Published
- 1975-01-01
- Volume
- 111
- Issue
- 1
- Pages
- 40-40
- ISSN
- 0003-987X (ISSN-L)
- OpenAlex
- W1986669980
- Cited by
- 449
- References
- 0
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A New Formula for Depigmenting Human Skin. https://app.cochat.ai/papers/10.1001/archderm.111.1.40
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- Kligman, A. M. (1975). A New Formula for Depigmenting Human Skin. Archives of Dermatology. https://doi.org/10.1001/archderm.111.1.40
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
