Cited by 1,269Schizophrenia research and treatmentPsychopathy, Forensic Psychiatry, Sexual OffendingBipolar Disorder and Treatment

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Prediction of Psychosis in Youth at High Clinical Risk: A Multisite Longitudinal Study in North America

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Cannon, Tyrone D., Cadenhead, Kristin, Cornblatt, Barbara, Woods, Scott W., Addington, Jean, Walker, Elaine, Seidman, Larry J., Perkins, Diana, Tsuang, Ming, McGlashan, Thomas, Heinssen, Robert·2008·Archives of General Psychiatry

DOI 10.1001/archgenpsychiatry.2007.3PMC PMC3065347

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Abstract

CONTEXT: Early detection and prospective evaluation of individuals who will develop schizophrenia or other psychotic disorders are critical to efforts to isolate mechanisms underlying psychosis onset and to the testing of preventive interventions, but existing risk prediction approaches have achieved only modest predictive accuracy. OBJECTIVES: To determine the risk of conversion to psychosis and to evaluate a set of prediction algorithms maximizing positive predictive power in a clinical high-risk sample. DESIGN, SETTING, AND PARTICIPANTS: Longitudinal study with a 2 1/2-year follow-up of 291 prospectively identified treatment-seeking patients meeting Structured Interview for Prodromal Syndromes criteria. The patients were recruited and underwent evaluation across 8 clinical research centers as part of the North American Prodrome Longitudinal Study. MAIN OUTCOME MEASURE: Time to conversion to a fully psychotic form of mental illness. RESULTS: The risk of conversion to psychosis was 35%, with a decelerating rate of transition during the 2 1/2-year follow-up. Five features assessed at baseline contributed uniquely to the prediction of psychosis: a genetic risk for schizophrenia with recent deterioration in functioning, higher levels of unusual thought content, higher levels of suspicion/paranoia, greater social impairment, and a history of substance abuse. Prediction algorithms combining 2 or 3 of these variables resulted in dramatic increases in positive predictive power (ie, 68%-80%) compared with the prodromal criteria alone. CONCLUSIONS: These findings demonstrate that prospective ascertainment of individuals at risk for psychosis is feasible, with a level of predictive accuracy comparable to that in other areas of preventive medicine. They provide a benchmark for the rate and shape of the psychosis risk function against which standardized preventive intervention programs can be compared.

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KAUFMAN, J., BIRMAHER, B., BRENT, D., RAO, U., FLYNN, C., MORECI, P., WILLIAMSON, D., & RYAN, N. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199707000-00021 · Cited by 10,148
Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental States
Yung, A. R., Yung, A. R., Yuen, H. P., McGorry, P. D., Phillips, L., Kelly, D., Dell’Olio, M., Francey, S. M., Cosgrave, E., Killackey, E. J., et al. (2005) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2005.01714.x · Cited by 2,284
The Family History Method Using Diagnostic Criteria
Andreasen, N. C. (1977) · Archives of General Psychiatry · doi:10.1001/archpsyc.1977.01770220111013 · Cited by 1,903
Prodromal Assessment With the Structured Interview for Prodromal Syndromes and the Scale of Prodromal Symptoms: Predictive Validity, Interrater Reliability, and Training to Reliability
Miller, T. J., McGlashan, T. H., Rosen, J. L., Cadenhead, K. S., Ventura, J., McFarlane, W. R., Perkins, D. O., Pearlson, G. D., & Woods, S. W. (2003) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a007040 · Cited by 1,800
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(2018) · Sage eBooks · doi:10.4135/9781506326139.n198 · Cited by 1,244
The Prodromal Phase of First-episode Psychosis: Past and Current Conceptualizations
Yung, A. R., & McGorry, P. D. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.2.353 · Cited by 1,168
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Self-citation
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Self-citation
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Squarcina, L., Kambeitz‐Ilankovic, L., Bonivento, C., Prunas, C., Oldani, L., Wenzel, J., Ruef, A., Dwyer, D., Ferro, A., Borgwardt, S., et al. (2022) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2021.2014955 · Cited by 7
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Self-citation
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Thompson, E. C., Visser, K., Schiffman, J., Spirito, A., Hunt, J., & Wolff, J. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.114322 · Cited by 4
Are factors that predict conversion to psychosis associated with initial transition to a high risk state? An adolescent brain cognitive development study analysis
Smucny, J., Wood, A., Davidson, I. N., & Carter, C. S. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.08.022 · Cited by 6
Associations between number of different type of care meetings with social network and improvement in mental well‐being in adolescents at risk of first‐episode psychosis
Granö, N., Karjalainen, M., Anto, J., Itkonen, A., Edlund, V., & Roine, M. (2011) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2011.00269.x · Cited by 5
Revisions and refinements of the diagnosis of schizophrenia in DSM‐5.
Reddy, L. F., Horan, W. P., & Green, M. F. (2014) · Clinical Psychology Science and Practice · doi:10.1111/cpsp.12071 · Cited by 5
Providing care to young people with emerging risk of psychosis: balancing potential risks and benefits
McGorry, P. D., Nelson, B., & Goldstone, S. D. (2012) · Clinical Practice · doi:10.2217/cpr.12.69 · Cited by 5
Assessment and treatment of the risk of psychosis in adolescents--a review.
Zdanowicz, N., Mees, L., Jacques, D., Tordeurs, D., & Reynaert, C. (2014) · PubMed · Cited by 5
Differential propensity in recognition of prepsychotic phenomena among psychiatrists, clinical psychologists and school counsellors
Liu, C., Chang, L., Tseng, H., Lai, M., & Hwu, H. (2010) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2010.00182.x · Cited by 5
Current Treatment Trends of Psychosis in Youth with Schizophrenia
Baker, K. K., Howell, C., & Findling, R. L. (2016) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-016-0066-9 · Cited by 5
Relationship between Sleep and Psychosis in the Pediatric Population: A Brief Review
Bordoloi, M., & Ramtekkar, U. P. (2018) · Medical Sciences · doi:10.3390/medsci6030076 · Cited by 5
Transition to Psychosis: Evaluation of the First-Degree Relatives of Patients with Schizophrenia .
Hormozpour‎, M., Amini‎, H., Pajouhanfar‎, S., Faghankhani, M., Rahmani, A., & Sharifi‎, V. (2016) · Europe PMC (PubMed Central) · Cited by 5
Specific disorders: the impact on children, parenting, and family relationships
Reupert, A., Maybery, D. J., Nicholson, J., Göpfert, M., & Seeman, M. V. (2015) · Cambridge University Press eBooks · doi:10.1017/cbo9781107707559.012 · Cited by 5
Personalisierte Medizin in der Psychiatrie und Psychotherapie
Koutsouleris, N., Ruhrmann, S., Falkai, P., & Maier, W. (2013) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s00103-013-1840-0 · Cited by 5
Comparison of measures of functioning for use with treatment‐seeking adolescents experiencing attenuated symptoms of psychosis
Wilson, C. S., Kline, E. R., Thompson, E., Demro, C., Pitts, S. C., Bussell, K., Reeves, G. M., & Schiffman, J. E. (2014) · Early Intervention in Psychiatry · doi:10.1111/eip.12189 · Cited by 5
Psychotic‐spectrum symptoms, cumulative adversity exposure and substance use among high‐risk girls
Lansing, A. E., Plante, W. Y., Fennema‐Notestine, C., Golshan, S., & Beck, A. N. (2017) · Early Intervention in Psychiatry · doi:10.1111/eip.12533 · Cited by 5
Psychosis Risk Syndrome: What Now?
Sentissi, O., ANDREOU, M. A., Moeglin, C., Curtis, L., & BROSCH, M. S. (2017) · Journal of Psychiatric Practice · doi:10.1097/pra.0000000000000272 · Cited by 5
The Prodrome of Schizophrenia
Addington, J., & Lewis, S. W. (2010) · Wiley eBooks · doi:10.1002/9781444327298.ch6 · Cited by 4
Self-citation
Should the diagnostic boundaries of schizophrenia be expanded?
David, A. S. (2011) · Cognitive Neuropsychiatry · doi:10.1080/13546805.2011.554276 · Cited by 5
[Study of the first psychotic episode and its prodromic phases in Mexico].
Nicolini, H. (2009) · PubMed · Cited by 5
Taking the edge off: a feasibility randomized controlled trial of an online mindfulness-based intervention to reduce suspiciousness/paranoia in high positive schizotypy
McDonald, H., Valmaggia, L., Antonova, E., & Chadwick, P. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2024.1380077 · Cited by 5
Duration of untreated illness in psychosis: conceptualising duration of the psychosis prodrome and duration of untreated psychosis in predicting outcome and refining early intervention
Waddington, J. L., Nkire, N., Kinsella, A., Russell, V., & Clarke, M. (2025) · Psychiatry Research Communications · doi:10.1016/j.psycom.2025.100232 · Cited by 4
Early Detection of Psychosis: Recent Updates from Clinical High-Risk Research
Schvarcz, A., & Bearden, C. E. (2015) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-015-0033-6 · Cited by 5
Perspective on clinical high-risk for psychosis in Africa
Awhangansi, S., Okewole, A., Archard, P. J., & O’Reilly, M. J. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1226012 · Cited by 5
Timeframe for Conversion to Psychosis From Individuals at Clinical High-Risk: A Quantile Regression
Zhang, T., Wei, Y., Tang, X., Xu, L., Hu, Y., Liu, H., Wang, Z., Chen, T., Li, C., & Wang, J. (2024) · Schizophrenia Bulletin · doi:10.1093/schbul/sbae129 · Cited by 5
A prognostic model for predicting functional impairment in youth mental health services
Iorfino, F., Oliveira, R., Cripps, S., Marchant, R., Varidel, M., Capon, W., Crouse, J. J., Prodan, A., Scott, E. M., Scott, J. L., et al. (2024) · European Psychiatry · doi:10.1192/j.eurpsy.2024.1787 · Cited by 6
DSM-5
Friedman, N. D. B., Sadhu, J. M., & Jellinek, M. S. (2011) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0b013e3182435c5a · Cited by 4
Emotional Dysregulation, Attributional Bias, Neurocognitive Impairment in Individuals at Ultra-High Risk for Psychosis and with Schizophrenia : Its Association with Paranoia
Kim, N. W., Song, Y. Y., Park, J. Y., Baek, S. Y., Kang, J. I., Lee, E. M., & An, S. K. (2014) · Korean Journal of Schizophrenia Research · doi:10.16946/kjsr.2014.17.2.63 · Cited by 5
Very Early Interventions in Psychotic Disorders
Bhangoo, R. K., & Carter, C. S. (2009) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2008.10.003 · Cited by 4
Urinary biopyrrins and free immunoglobin light chains are biomarker candidates for screening at‐risk mental state in adolescents
Wake, R., Araki, T., Fukushima, M., Matsuda, H., Inagaki, T., Hayashida, M., Hashioka, S., Horiguchi, J., Inagaki, M., Miyaoka, T., et al. (2021) · Early Intervention in Psychiatry · doi:10.1111/eip.13154 · Cited by 4
Analysis of the Middle and Long Latency ERP Components in Schizophrenia
Costa, M. R. E., Teixeira, F., & Teixeira, J. P. (2021) · Communications in computer and information science · doi:10.1007/978-3-030-91885-9_35 · Cited by 4
The 2nd Schizophrenia International Research Society Conference, 10–14 April 2010, Florence, Italy: Summaries of oral sessions
Baharnoori, M., Bartholomeusz, C., Boucher, A. A., Buchy, L., Chaddock, C., Chiliza, B., Föcking, M., Fornito, A., Gallego, J. A., Hori, H., et al. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.09.008 · Cited by 6
Validation of the Arabic Version of the Psychotic-Like Experiences Questionnaire for Children (PLEQ-C) in a Community Sample of Children and Adolescents Aged 12–18 years
Fekih‐Romdhane, F., Malaeb, D. N., Obeïd, S., Dabbous, M., Sakr, F., Hallit, R. R., & Hallit, S. R. (2023) · International Journal of Mental Health and Addiction · doi:10.1007/s11469-023-01133-8 · Cited by 4

Authors: Cannon, T. D., Cadenhead, K., Cornblatt, B., Woods, S. W., Addington, J., Walker, E., Seidman, L. J., Perkins, D., Tsuang, M., McGlashan, T., & Heinssen, R.
Affiliations: University of California, Los Angeles (US)
University of California San Diego (US)
Zucker Hillside Hospital (US)
Yale University (US)
University of Toronto (CA)
Emory University (US)
Harvard University (US)
University of North Carolina at Chapel Hill (US)
National Institute of Mental Health (US)
ORCID: Cannon, Tyrone D.
Cadenhead, Kristin
Cornblatt, Barbara
Woods, Scott W.
Addington, Jean
Walker, Elaine
Seidman, Larry J.
Perkins, Diana
Tsuang, Ming
McGlashan, Thomas
Venue: Archives of General Psychiatry
Publisher: American Medical Association (AMA)
Published: 2008-01-01
Volume: 65
Issue: 1
Pages: 28
ISSN: 0003-990X (ISSN-L)
DOI: 10.1001/archgenpsychiatry.2007.3
PMC: PMC3065347
OpenAlex: W2140824803
Cited by: 1,269
References: 68
Citations by year: 2026: 14 · 2025: 22 · 2024: 19 · 2023: 30 · 2022: 32 · 2021: 52 · 2020: 51 · 2019: 72 · 2018: 50 · 2017: 80 · 2016: 91 · 2015: 98 · 2014: 93 · 2013: 115 · 2012: 109
FWCI: 78.94
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Archives of General Psychiatry (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (UL1TR000454)
National Institute of Mental Health (K24MH076191, K23MH001905, U01MH082022, R01MH060720, U01MH082004, U01MH081944)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords: psychosis prediction, clinical high risk for psychosis, schizophrenia, transition to psychosis, risk prediction algorithm, unusual thought content, social dysfunction, substance abuse, North American Prodrome Longitudinal Study
MeSH terms: Adolescent, Adult, Algorithms, Cognition, Female, Humans, Longitudinal Studies, Male, Paranoid Disorders, Predictive Value of Tests, Prognosis, Psychotic Disorders, Risk Factors, Schizophrenia, Social Behavior, Syndrome, Antipsychotic Agents, Substance-Related Disorders, Genetic Predisposition to Disease, Kaplan-Meier Estimate

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Prediction of Psychosis in Youth at High Clinical Risk: A Multisite Longitudinal Study in North America

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