Cited by 1,269Schizophrenia research and treatmentPsychopathy, Forensic Psychiatry, Sexual OffendingBipolar Disorder and Treatment

The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.

Prediction of Psychosis in Youth at High Clinical Risk: A Multisite Longitudinal Study in North America

Open access

Cannon, Tyrone D., Cadenhead, Kristin, Cornblatt, Barbara, Woods, Scott W., Addington, Jean, Walker, Elaine, Seidman, Larry J., Perkins, Diana, Tsuang, Ming, McGlashan, Thomas, Heinssen, Robert·2008·Archives of General Psychiatry

DOI 10.1001/archgenpsychiatry.2007.3PMC PMC3065347

Open this paper in CoChat — free account

Abstract

CONTEXT: Early detection and prospective evaluation of individuals who will develop schizophrenia or other psychotic disorders are critical to efforts to isolate mechanisms underlying psychosis onset and to the testing of preventive interventions, but existing risk prediction approaches have achieved only modest predictive accuracy. OBJECTIVES: To determine the risk of conversion to psychosis and to evaluate a set of prediction algorithms maximizing positive predictive power in a clinical high-risk sample. DESIGN, SETTING, AND PARTICIPANTS: Longitudinal study with a 2 1/2-year follow-up of 291 prospectively identified treatment-seeking patients meeting Structured Interview for Prodromal Syndromes criteria. The patients were recruited and underwent evaluation across 8 clinical research centers as part of the North American Prodrome Longitudinal Study. MAIN OUTCOME MEASURE: Time to conversion to a fully psychotic form of mental illness. RESULTS: The risk of conversion to psychosis was 35%, with a decelerating rate of transition during the 2 1/2-year follow-up. Five features assessed at baseline contributed uniquely to the prediction of psychosis: a genetic risk for schizophrenia with recent deterioration in functioning, higher levels of unusual thought content, higher levels of suspicion/paranoia, greater social impairment, and a history of substance abuse. Prediction algorithms combining 2 or 3 of these variables resulted in dramatic increases in positive predictive power (ie, 68%-80%) compared with the prodromal criteria alone. CONCLUSIONS: These findings demonstrate that prospective ascertainment of individuals at risk for psychosis is feasible, with a level of predictive accuracy comparable to that in other areas of preventive medicine. They provide a benchmark for the rate and shape of the psychosis risk function against which standardized preventive intervention programs can be compared.

Integrity signals

Registry

Crossref · 10.1001/archgenpsychiatry.2007.3

Cites

68 of 68 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial Reliability and Validity Data
KAUFMAN, J., BIRMAHER, B., BRENT, D., RAO, U., FLYNN, C., MORECI, P., WILLIAMSON, D., & RYAN, N. (1997) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199707000-00021 · Cited by 10,148
Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental States
Yung, A. R., Yung, A. R., Yuen, H. P., McGorry, P. D., Phillips, L., Kelly, D., Dell’Olio, M., Francey, S. M., Cosgrave, E., Killackey, E. J., et al. (2005) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2005.01714.x · Cited by 2,284
The Family History Method Using Diagnostic Criteria
Andreasen, N. C. (1977) · Archives of General Psychiatry · doi:10.1001/archpsyc.1977.01770220111013 · Cited by 1,903
Prodromal Assessment With the Structured Interview for Prodromal Syndromes and the Scale of Prodromal Symptoms: Predictive Validity, Interrater Reliability, and Training to Reliability
Miller, T. J., McGlashan, T. H., Rosen, J. L., Cadenhead, K. S., Ventura, J., McFarlane, W. R., Perkins, D. O., Pearlson, G. D., & Woods, S. W. (2003) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a007040 · Cited by 1,800
Self-citation
Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison
Pantelis, C., Velakoulis, D., McGorry, P. D., Wood, S. J., John Suckling, A., Phillips, L., Yung, A. R., Bullmore, E. T., Brewer, W. J., Soulsby, B., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12323-9 · Cited by 1,309
Diagnostic and Statistical Manual of Mental Disorders
(2018) · Sage eBooks · doi:10.4135/9781506326139.n198 · Cited by 1,244
The Prodromal Phase of First-episode Psychosis: Past and Current Conceptualizations
Yung, A. R., & McGorry, P. D. (1996) · Schizophrenia Bulletin · doi:10.1093/schbul/22.2.353 · Cited by 1,168
Psychosis prediction: 12-month follow up of a high-risk ("prodromal") group
Yung, A. R., Phillips, L. J., Yuen, H. P., Francey, S. M., McFarlane, C. A., Hallgren, M., & McGorry, P. D. (2003) · Schizophrenia Research · doi:10.1016/s0920-9964(02)00167-6 · Cited by 1,136
Randomized Controlled Trial of Interventions Designed to Reduce the Risk of Progression to First-Episode Psychosis in a Clinical Sample With Subthreshold Symptoms
McGorry, P. D., Yung, A. R., Phillips, L. J., Yuen, H. P., Francey, S., Cosgrave, E. M., Germano, D., Bravin, J., McDonald, T., Blair, A., et al. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.10.921 · Cited by 1,056

Show all 68 references

Sorted by citations

Items 701–800 of 1,000

Prisoners at ultra-high-risk for psychosis: a cross-sectional study
Jarrett, M., Valmaggia, L., Parrott, J. M., Forrester, A., Winton‐Brown, T., Maguire, H., Ndegwa, D., McGuire, P. K., & Craig, T. (2015) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796015000062 · Cited by 19
Computational Psychiatry: Embracing Uncertainty and Focusing on Individuals, Not Averages
Chekroud, A. M., Lane, C. E., & Ross, D. A. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.07.011 · Cited by 19
Intervention for cannabis use in young people at ultra high risk for psychosis and in early psychosis
Bucci, S., Baker, A., Halpin, S. A., Hides, L. M., Lewin, T. J., Carr, V. J., & Startup, M. (2010) · Mental Health and Substance Use · doi:10.1080/17523280903523983 · Cited by 19
Functional Capacity Assessed by the Map Task in Individuals at Clinical High-Risk for Psychosis
McLaughlin, D., Carrión, R. E., Auther, A. M., Olvet, D. M., Addington, J., Bearden, C. E., Cadenhead, K. S., Cannon, T. D., HEINSSEN, R. K., Mathalon, D. H., et al. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw039 · Cited by 19
Self-citation
Two-Year Clinical and Functional Outcomes of an Asian Cohort at Ultra-High Risk of Psychosis
Chan, C. T., Abdin, E., Subramaniam, M., Tay, S. A., Lim, L. K., & Verma, S. K. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00758 · Cited by 19
Detecting schizophrenia early: Prediagnosis healthcare utilization characteristics of patients with schizophrenia may aid early detection
Wallace, A. E., Isenberg, K. E., York, W., Shinde, M. U., Barron, J. O., Franchino‐Elder, J., Sand, M. S., & Sidovar, M. F. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.08.011 · Cited by 18
Coping with family stress in individuals at clinical high-risk for psychosis
Yee, C., Gupta, T., Mittal, V. A., & Haase, C. M. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.11.057 · Cited by 23
Leveraging big data to map neurodevelopmental trajectories in pediatric anxiety
Zacharek, S. J., Kribakaran, S., Kitt, E. R., & Gee, D. G. (2021) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2021.100974 · Cited by 18
Young people at ultra high risk for psychosis: research from the PACE clinic
Yung, A. R., & Nelson, B. (2011) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462011000600003 · Cited by 20
A supplementary circuit rule-set for the neuronal wiring
Vadakkan, K. I. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00170 · Cited by 20
Longitudinal change in neurocognition and its relation to symptomatic and functional changes over 2 years in individuals at clinical high-risk for psychosis
Shin, Y. S., Kim, S.-Y., Lee, T. Y., Hur, J., Shin, N. Y., Kim, S. N., Shin, M., & Kwon, J. S. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.03.024 · Cited by 19
Concerns about genetic testing for schizophrenia among young adults at clinical high risk for psychosis
Lawrence, R. E., Friesen, P., Brucato, G., Girgis, R. R., & Dixon, L. B. (2015) · AJOB Empirical Bioethics · doi:10.1080/23294515.2015.1084553 · Cited by 19
Olfaction and schizophrenia clinical risk status: Just the facts
Turetsky, B. I., Kamath, V. J., Calkins, M. E., Brewer, W. J., Wood, S. J., Pantelis, C., Seidman, L. J., Malaspina, D., Good, K. P., Kopala, L. C., et al. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.04.016 · Cited by 19
Self-citation
The New England family study high‐risk project: Neurological impairments among offspring of parents with schizophrenia and other psychoses
Buka, S. L., Seidman, L. J., Tsuang, M. T., & Goldstein, J. M. (2013) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32181 · Cited by 18
Self-citation
Evidence for an agitated–aggressive syndrome predating the onset of psychosis
Huber, C. G., Smieskova, R., Schroeder, K., Studerus, E., Harrisberger, F., Aston, J., Walter, A., Walter, M., Riecher‐Rössler, A., & Borgwardt, S. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.06.014 · Cited by 18
Alterations in white matter microstructure in individuals at persistent risk for psychosis
Roalf, D., Garza, Á. G. D. L., Rosen, A. F. G., Calkins, M., Moore, T. M., Quarmley, M., Ruparel, K., Xia, C., Rupert, P. E., Satterthwaite, T., et al. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0360-1 · Cited by 19
Early childhood social communication deficits in youth at clinical high-risk for psychosis: Associations with functioning and risk
Osborne, K. J., Vargas, T., & Mittal, V. A. (2019) · Development and Psychopathology · doi:10.1017/s0954579419000385 · Cited by 19
Individualized Prediction of Prodromal Symptom Remission for Youth at Clinical High Risk for Psychosis
Worthington, M., Addington, J., Bearden, C. E., Cadenhead, K. S., Cornblatt, B. A., Keshavan, M. S., Mathalon, D. H., McGlashan, T. H., Perkins, D. O., Stone, W. S., et al. (2021) · Schizophrenia Bulletin · doi:10.1093/schbul/sbab115 · Cited by 18
Self-citation
Demographic correlates of attenuated positive psychotic symptoms
Waford, R., MacDonald, A. N., Goines, K., Novacek, D. M., Trotman, H. D., Walker, E. F., Addington, J., Bearden, C. E., Cadenhead, K. S., Cannon, T. D., et al. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.04.035 · Cited by 18
Self-citation
Clinical Usefulness of Second-Generation Antipsychotics in Treating Children and Adolescents Diagnosed with Bipolar or Schizophrenic Disorders
Gentile, S. (2011) · Pediatric Drugs · doi:10.2165/11591250-000000000-00000 · Cited by 18
Different vulnerability indicators for psychosis and their neuropsychological characteristics in the Northern Finland 1986 Birth Cohort
Mukkala, S., Ilonen, T., Nordström, T., Miettunen, J., Loukkola, J., Barnett, J. H., Murray, G. K., Jääskeläinen, E., Mäki, P. H., Taanila, A. M., et al. (2011) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2010.524148 · Cited by 18
Neurocognition and Motor Functioning in the Prediction of Psychosis
Studerus, E., Papmeyer, M., & Riecher‐Rössler, A. (2016) · Key issues in mental health (Online)/Key issues in mental health (Print) · doi:10.1159/000440919 · Cited by 20
Utility of Washington Early Recognition Center Self-Report Screening Questionnaires in the Assessment of Patients with Schizophrenia and Bipolar Disorder
Hsieh, C. J., Godwin, D., & Mamah, D. T. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00149 · Cited by 19
Deconstructing the relationships between self‐esteem and paranoia in early psychosis: an experience sampling study
Monsonet, M., Kwapil, T. R., & Neus Barrantes-vidal, A. (2020) · British Journal of Clinical Psychology · doi:10.1111/bjc.12263 · Cited by 20
The Impact of Psychosis on Sexual Functioning: A Systematic Review
Vargas-Cáceres, S., Cera, N., Nobre, P. J., & Ramos‐Quiroga, J. A. (2021) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.12.007 · Cited by 20
Neurochemical Imaging in Schizophrenia
Urban, N., & Abi‐Dargham, A. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_37 · Cited by 18
Bridging Bench and Practice: Translational Research for Schizophrenia and Other Psychotic Disorders
Wang, P. S., HEINSSEN, R. K., Oliveri, M., Wagner, A., & Goodman, W. K. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.170 · Cited by 18
Self-citation
Prolonged cortical silent period among drug-naive subjects at ultra-high risk of psychosis
Tang, Y., Zhang, T., Edelman, B. J., Zeng, B., Zhao, S., Li, C., Zhuo, K., Qian, Z., Li, H., Guo, Q., et al. (2014) · Schizophrenia Research · doi:10.1016/j.schres.2014.10.004 · Cited by 18
Short clinically-based prediction model to forecast transition to psychosis in individuals at clinical high risk state
Kotlicka‐Antczak, M., Karbownik, M. S., Stawiski, K., Pawełczyk, A. M., Żurner, N., Pawełczyk, T., Strzelecki, D., & Fusar‐Poli, P. (2019) · European Psychiatry · doi:10.1016/j.eurpsy.2019.02.007 · Cited by 19
The prognostic significance of attenuated psychotic symptoms in help-seeking youth
Hazan, H., Spelman, T. D., Amminger, G. P., Hickie, I. B., McGorry, P. D., Phillips, L., Purcell, R., Wood, S. J., Yung, A. R., & Nelson, B. (2019) · Schizophrenia Research · doi:10.1016/j.schres.2019.10.016 · Cited by 21
Epidemiology of Schizophrenia
Eaton, W. W., Chen, C., & Bromet, E. J. (2011) · Wiley eBooks · doi:10.1002/9780470976739.ch16 · Cited by 18
A randomised double-blind placebo-controlled trial of minocycline and/or omega-3 fatty acids added to treatment as usual for at risk Mental States: The NAYAB study
Qurashi, I., Chaudhry, I. B., Khoso, A. B., Husain, M. O., Hafeez, D., Kiran, T., Lane, S., Naqvi, H., Minhas, F. A., Nizami, A. T., et al. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.10.025 · Cited by 17
Movement disorders are associated with schizotypy in unaffected siblings of patients with non-affective psychosis
Koning, J., Tenback, D. E., Kahn, R. S., Vollema, M. G., Cahn, W., & van Harten, P. N. (2011) · Psychological Medicine · doi:10.1017/s0033291711000389 · Cited by 17
Dimensional and discrete variations on the psychosis continuum in a Dutch crowd-sourcing population sample
Wigman, J. T. W., Wardenaar, K. J., Wanders, R. B. K., Booij, S. H., Jeronimus, B. F., van der Krieke, L., Wichers, M., & de Jonge, P. (2016) · European Psychiatry · doi:10.1016/j.eurpsy.2016.11.014 · Cited by 18
Impairment in Social Functioning differentiates youth meeting Ultra-High Risk for psychosis criteria from other mental health help-seekers: A validation of the Italian version of the Global Functioning: Social and Global Functioning: Role scales
Cascio, N. L., Curto, M., Pasqualetti, P., Lindau, J. F., Girardi, N., Saba, R., Brandizzi, M., Monducci, E., Masillo, A., Colafrancesco, G., et al. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.04.008 · Cited by 17
Self-citation
Selection for psychosocial treatment for youth at clinical high risk for psychosis based on the North American Prodrome Longitudinal Study individualized risk calculator
Worthington, M., Miklowitz, D. J., O’Brien, M. P., Addington, J., Bearden, C. E., Cadenhead, K. S., Cornblatt, B. A., Mathalon, D. H., McGlashan, T. H., Perkins, D. O., et al. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.12914 · Cited by 17
Self-citation
Risks and Protective Factors of the Prodromal Stage of Psychosis: A Literature Review
Althwanay, A., Al-Zamil, N. A., Almukhadhib, O. Y., Alkhunaizi, S., & Althwanay, R. (2020) · Cureus · doi:10.7759/cureus.8639 · Cited by 15
The Relationship between PID-5 Personality Traits and Mental States. A Study on a Group of Young Adults at Risk of Psychotic Onset
Meliante, M., Rossi, C., Malvini, L., Niccoli, C., Oasi, O., Barbera, S., & Percudani, M. (2021) · Medicina · doi:10.3390/medicina57010033 · Cited by 17
Abnormally Large Baseline P300 Amplitude Is Associated With Conversion to Psychosis in Clinical High Risk Individuals With a History of Autism: A Pilot Study
Foss‐Feig, J. H., Guillory, S. B., Roach, B. J., Velthorst, E., Hamilton, H., Bachman, P., Belger, A., Carrión, R. E., Duncan, E., Johannesen, J., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.591127 · Cited by 17
Self-citation
Strategies for Effective Recruitment of Individuals at Risk for Developing Psychosis
Domingues, I., Alderman, T., & Cadenhead, K. (2011) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2011.00278.x · Cited by 19
Self-citation
Visual information processing dysfunction across the developmental course of early psychosis
Perez, V. B., Shafer, K. M., & Cadenhead, K. S. (2012) · Psychological Medicine · doi:10.1017/s0033291712000426 · Cited by 17
Self-citation
Neural Dysfunction in Cognitive Control Circuits in Persons at Clinical High-Risk for Psychosis
Colibazzi, T., Horga, G., Wang, Z., Huo, Y., Corcoran, C. M., Klahr, K., Brucato, G., Girgis, R. R., Gill, K. E., Abi‐Dargham, A., et al. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.273 · Cited by 16
Imaging and Genetic Biomarkers Predicting Transition to Psychosis
Hunter, S. A., & Lawrie, S. M. (2018) · Current topics in behavioral neurosciences · doi:10.1007/7854_2018_46 · Cited by 17
DSM‐5 and the ‘Psychosis Risk Syndrome’: The DSM‐5 proposal is better than DSM‐IV
Woods, S. W., Carlson, J., & McGlashan, T. H. (2010) · Psychosis · doi:10.1080/17522439.2010.511719 · Cited by 17
Self-citation
Expanding the Boundaries of Early Intervention for Psychosis: Intervening During the Prodrome
Auther, A. M., Gillett, D. A., & Cornblatt, B. A. (2008) · Psychiatric Annals · doi:10.3928/00485713-20080801-02 · Cited by 17
Self-citation
Poor outcome associated with symptomatic deterioration among help‐seeking individuals at risk for psychosis: a naturalistic follow‐up study
Morita, K., Kobayashi, H., Takeshi, K., Tsujino, N., Nemoto, T., & Mizuno, M. (2014) · Early Intervention in Psychiatry · doi:10.1111/eip.12032 · Cited by 16
The Changing Legal Landscape of Cannabis Use and Its Role in Youth-onset Psychosis
Wright, A., Cather, C., Gilman, J., & Evins, A. E. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2019.08.016 · Cited by 16
Diagnostic précoce dans la schizophrénie : une mission pour les médecins généralistes ?
Galudec, M. L., Stéphan, F., Mascret, R., Bourgin, J., & Walter, M. (2010) · La Presse Médicale · doi:10.1016/j.lpm.2010.09.015 · Cited by 16
Personality disorders in children and adolescents.
Shiner, R. L., & Tackett, J. L. (2014) · Cited by 16
Antipsychotic treatment of UHR (‘prodromal’) individuals
Yung, A. R. (2010) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2010.00191.x · Cited by 16
Obstetric complications and risk for conversion to psychosis among individuals at high clinical risk
Mittal, V. A., Willhite, R., Daley, M. L., Bearden, C. E., Niendam, T. A., Ellman, L. M., & Cannon, T. D. (2009) · Early Intervention in Psychiatry · doi:10.1111/j.1751-7893.2009.00137.x · Cited by 16
Self-citation
Defining Treatment as Usual for Attenuated Psychosis Syndrome: A Survey of Community Practitioners
Jacobs, E., Kline, E. R., & Schiffman, J. E. (2012) · Psychiatric Services · doi:10.1176/appi.ps.201200045 · Cited by 16
fMRI responses to emotional faces in children and adolescents at genetic risk for psychiatric illness share some of the features of depression
Barbour, T. A., Pruitt, P. J., & Diwadkar, V. A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.11.036 · Cited by 18
Clinical Staging in the Pathophysiology of Psychotic and Affective Disorders: Facilitation of Prognosis and Treatment
Archer, T., Kostrzewa, R. M., Palomo, T., & Beninger, R. J. (2010) · Neurotoxicity Research · doi:10.1007/s12640-010-9161-7 · Cited by 16
Beyond “Cold” Cognition: Exploring Cognitive Control of Emotion as a Risk Factor for Psychosis
Tully, L. M., & Niendam, T. A. (2014) · Current Behavioral Neuroscience Reports · doi:10.1007/s40473-014-0016-z · Cited by 17
Toward an interdisciplinary science of adolescence: Insights from schizophrenia research
Kasai, K. (2012) · Neuroscience Research · doi:10.1016/j.neures.2012.12.001 · Cited by 16
Can cognitive deficits facilitate differential diagnosis between at‐risk mental state for psychosis and depressive disorders?
Schulze, C., Zimmermann, R., Gschwandtner, U., Pflueger, M. O., Rapp, C., Studerus, E., & Riecher‐Rössler, A. (2012) · Early Intervention in Psychiatry · doi:10.1111/eip.12004 · Cited by 16
The associations between quality of life and clinical symptoms in individuals with an at-risk mental state and first-episode psychosis
Ohmuro, N., Matsumoto, K., Ishii, Y., Katsura, M., Obara, C., Kikuchi, T., Hamaie, Y., Ito, F., & Matsuoka, H. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.04.031 · Cited by 15
The activity of enzymes of glutathione metabolism in blood cells of patients with a high risk of manifestation of endogenous psychoses and patients with the first psychotic episode
Prokhorova, T. A., Терешкина, Е. Б., Savushkina, O. K., Бокша, И. С., Vorobyeva, E. A., Omelchenko, M. A., Николаевич, П. А., Каледа, В. Г., & Burbaeva, G. S. (2019) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro201911904147 · Cited by 16
Sex differences in symptomatology of psychosis-risk patients and in prediction of psychosis
Rosen, M., Haidl, T. K., Ruhrmann, S., Vogeley, K., & Schultze-Lutter, F. (2020) · Archives of Women's Mental Health · doi:10.1007/s00737-019-01000-3 · Cited by 16
Personality Traits as Markers of Psychosis Risk in Kenya: Assessment of Temperament and Character
Mamah, D. T., Cloninger, C. R., Mutiso, V., Gitonga, I., Tele, A., & Ndetei, D. M. (2020) · Schizophrenia Bulletin Open · doi:10.1093/schizbullopen/sgaa051 · Cited by 16
Decreased Gamma Auditory Steady-State Response Is Associated With Impaired Real-World Functioning in Unmedicated Patients at Clinical High Risk for Psychosis
Ahmed, S., Lepock, J. R., Mizrahi, R., Bagby, R. M., Gerritsen, C. J., Korostil, M., Light, G. A., & Michael Kiang, A. (2020) · Clinical EEG and Neuroscience · doi:10.1177/1550059420982706 · Cited by 16
Microglial Activation and the Onset of Psychosis
Cannon, T. D. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15111377 · Cited by 16
Self-citation
Computerized Assessment of Psychosis Risk
Mittal, V. A., Ellman, L. M., Strauss, G. P., Walker, E. F., Corlett, P. R., Schiffman, J. E., Woods, S. W., Powers, A. R., Silverstein, S. M., Waltz, J. A., et al. (2021) · Journal of Psychiatry and Brain Science · doi:10.20900/jpbs.20210011 · Cited by 18
Self-citation
Hippocampal subfields, daily stressors, and resting cortisol in individuals at clinical high-risk for psychosis
Ristanovic, I., Vargas, T., Damme, K. S. F., & Mittal, V. A. (2022) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2022.105996 · Cited by 15
Recent Updates on Predicting Conversion in Youth at Clinical High Risk for Psychosis
Caballero, N., Machiraju, S. N., Diomino, A., Kennedy, L., Kadivar, A., & Cadenhead, K. S. (2023) · Current Psychiatry Reports · doi:10.1007/s11920-023-01456-2 · Cited by 17
Self-citation
Prävention psychotischer Störungen
Klosterkötter, J. (2013) · Der Nervenarzt · doi:10.1007/s00115-013-3831-7 · Cited by 15
Development of a stage-dependent prognostic model to predict psychosis in ultra-high-risk patients seeking treatment for co-morbid psychiatric disorders
Ising, H. K., Ruhrmann, S., Burger, N., Rietdijk, J., Dragt, S., Klaassen, R. M. C., van den Berg, D. P. G., Nieman, D. H., Boonstra, N., Linszen, D. H., et al. (2016) · Psychological Medicine · doi:10.1017/s0033291716000325 · Cited by 15
Disruptions in neural connectivity associated with reduced susceptibility to a depth inversion illusion in youth at ultra high risk for psychosis
Gupta, T., Silverstein, S. M., Bernard, J. A., Keane, B. P., Papathomas, T. V., Pelletier‐Baldelli, A., Dean, D. J., Newberry, R. E., Ristanovic, I., & Mittal, V. A. (2016) · NeuroImage Clinical · doi:10.1016/j.nicl.2016.09.022 · Cited by 17
Mind the prevalence rate: overestimating the clinical utility of psychiatric diagnostic classifiers
Abu-Akel, A. M., Bousman, C., Skafidas, E. S., & Pantelis, C. (2018) · Psychological Medicine · doi:10.1017/s0033291718000673 · Cited by 15
Association between Dopamine Receptor D2 (DRD2) Variations rs6277 and rs1800497 and Cognitive Performance According to Risk Type for Psychosis: A Nested Case Control Study in a Finnish Population Sample
Ramsay, H., Barnett, J. H., Miettunen, J., Mukkala, S., Mäki, P. H., Liuhanen, J., Murray, G. K., Järvelin, M., Ollila, H. M., Paunio, T., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127602 · Cited by 15
Perceived negative attitude of others as an early sign of psychosis
Salokangas, R., Heinimaa, M., Svirskis, T., Laine, T., Huttunen, J., Ristkari, T., Ilonen, T., Korkeila, J., Vaskelainen, L., Rekola, J., et al. (2009) · European psychiatry · doi:10.1016/j.eurpsy.2008.12.011 · Cited by 22
Outcome of Severe Obsessive-compulsive Disorder With Schizotypal Features: A Pilot Study
Huang, L.-C., Hwang, T., Huang, G., & Hwu, H. (2011) · Journal of the Formosan Medical Association · doi:10.1016/s0929-6646(11)60014-4 · Cited by 15
The psychometric properties of the Peters et al. Delusions Inventory (PDI) in Taiwan: reliability, validity, and utility
Kao, Y., Wang, T., Lu, C.-W., Cheng, T.-H., & Liu, Y. (2011) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-011-0428-y · Cited by 16
SCHIZOPHRENIA AND AUTISM/ASPERGER'S SYNDROME: OVERLAP AND DIFFERENCE
Fitzgerald, M. (2012) · Cited by 15
Development of a Boston Treatment Program for Youth at Clinical High Risk for Psychosis: Center for Early Detection, Assessment, and Response to Risk (CEDAR)
Friedman‐Yakoobian, M. S., West, M. L., Woodberry, K. A., O’Donovan, K., Zimmet, S. V., Gnong-Granato, A., Giuliano, A. J., Guyer, M. E., Rodenhiser, J., Keshavan, M. S., et al. (2018) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000181 · Cited by 15
Self-citation
Predicting psychosis risk using a specific measure of cognitive control: a 12-month longitudinal study
Guo, J. Y., Niendam, T. A., Auther, A. M., Carrión, R. E., Cornblatt, B. A., Ragland, J. D., Adelsheim, S. N., Calkins, R., Sale, T. G., Taylor, S. F., et al. (2019) · Psychological Medicine · doi:10.1017/s0033291719002332 · Cited by 17
Self-citation
A randomized Phase II trial evaluating efficacy, safety, and tolerability of oral BI 409306 in attenuated psychosis syndrome: Design and rationale
Keefe, R. S. E., Woods, S. W., Cannon, T. D., Ruhrmann, S., Mathalon, D. H., McGuire, P. K., Rosenbrock, H., Daniels, K., Cotton, D., Roy, D., et al. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.13083 · Cited by 14
Self-citation
Schizotypy and mindfulness: Magical thinking without suspiciousness characterizes mindfulness meditators
Antonova, E., Amaratunga, K., Wright, B., Ettinger, U., & Kumari, V. (2016) · Schizophrenia Research: Cognition · doi:10.1016/j.scog.2016.05.001 · Cited by 19
“Given that unusual beliefs and thought content constitute risk for psychosis conversion (Cannon et al., 2008), the reduction of self-referencing might be another rationale for mindfulness-based psychosis prevention.”
Background
Premorbid social adjustment and association with attenuated psychotic symptoms in clinical high-risk and help-seeking youth
Tarbox-Berry, S. I., Perkins, D. O., Woods, S. W., & Addington, J. (2018) · Psychological Medicine · doi:10.1017/s0033291717002343 · Cited by 14
Self-citation
Commentary about social avoidance and its significance in adolescents and young adults
Simon, A. E., Keller, P., & Cattapan, K. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.113718 · Cited by 14
Childhood Onset Diagnoses in a Case Series of Teens at Clinical High Risk for Psychosis
Mazzoni, P., Kimhy, D., Khan, S., Posner, K., Maayan, L. A., Eilenberg, M. E., Walsh‐Messinger, J., Kestenbaum, C. J., & Corcoran, C. M. (2009) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2008.0105 · Cited by 14
Early Detection and Intervention in Psychosis
Riecher‐Rössler, A., & McGorry, P. D. (2016) · Key issues in mental health (Online)/Key issues in mental health (Print) · doi:10.1159/000440924 · Cited by 14
Public Mental Health and Prevention
Radden, J. H. (2017) · Public Health Ethics · doi:10.1093/phe/phx011 · Cited by 14
Predicting the individual risk of psychosis conversion in at-risk mental state (ARMS): a multivariate model reveals the influence of nonpsychotic prodromal symptoms
Bourgin, J., Duchesnay, É., Magaud, E., Raphaël Gaillard, B., Kazès, M., & Krebs, M. (2019) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-019-01461-y · Cited by 14
Early Detection and Prevention of Schizophrenic Psychosis—A Review
Westhoff, M. S., Ladwig, J., Heck, J., Schülke, R., Groh, A., Deest, M., Bleich, S., Frieling, H., & Jahn, K. (2021) · Brain Sciences · doi:10.3390/brainsci12010011 · Cited by 14
Does a parent-report measure of behavioral problems enhance prediction of conversion to psychosis in clinical high-risk adolescents?
Simeonova, D. I., Attalla, A., Trotman, H. D., Esterberg, M. L., & Walker, E. F. (2011) · Schizophrenia Research · doi:10.1016/j.schres.2011.03.034 · Cited by 14
Self-citation
The Concept of Schizophrenia: From Unity to Diversity
Häfner, H. (2014) · Advances in Psychiatry · doi:10.1155/2014/929434 · Cited by 18
Fluctuating dermatoglyphic asymmetries in youth at ultrahigh-risk for psychotic disorders
Russak, O. D. F., Ives, L. T., Mittal, V. A., & Dean, D. J. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.12.013 · Cited by 15
A comparative study of psychotic and affective symptoms in Rwandan and Kenyan students
Owoso, A., Jansen, S., Ndetei, D. M., Musau, A., Mutiso, V., Mudenge, C., Ngirababyeyi, A., Gasovya, A., & Mamah, D. T. (2017) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796016001074 · Cited by 15
Outcome in patients converting to psychosis following a treated clinical high risk state
MALLA, A. K., de Bonneville, M., Shah, J. L., Jordan, G., Pruessner, M., Faridi, K., Rabinovitch, M., Iyer, S. N., & Joober, R. (2017) · Early Intervention in Psychiatry · doi:10.1111/eip.12431 · Cited by 14
The role of a family history of psychosis for youth at clinical high risk of psychosis
Georgopoulos, G., Stowkowy, J., Liu, L., Cadenhead, K. S., Cannon, T. D., Cornblatt, B. A., McGlashan, T. H., Perkins, D. O., Seidman, L. J., Tsuang, M. T., et al. (2017) · Early Intervention in Psychiatry · doi:10.1111/eip.12471 · Cited by 14
Self-citation
Social impairment and social language deficits in children and adolescents with and at risk for psychosis
D’Angelo, E. J., Morelli, N. M., Lincoln, S. H., Graber, K. M., Tembulkar, S. K., Gaudet, A., & Gonzalez–Heydrich, J. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.07.028 · Cited by 14
Imaging as Tool to Investigate Psychoses and Antipsychotics
Booij, J., & van Amelsvoort, T. (2012) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25761-2_12 · Cited by 14
Longitudinal and cross-sectional validation of the WERCAP screen for assessing psychosis risk and conversion
Mamah, D. T., Mutiso, V., & Ndetei, D. M. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.01.031 · Cited by 13
Patterns of Care for Adolescent With Schizophrenia: A Delphi-Based Consensus Study
Vita, A., Barlati, S., Bellomo, A., Fusar‐Poli, P., Masi, G., Nobili, L., Serafini, G., Zuddas, A., & Vicari, S. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.844098 · Cited by 13
Psychotic experiences, emotion regulation, and suicidal ideation among Chilean adolescents in the general population
Wastler, H. M., & Núñez, D. E. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.983250 · Cited by 13
Recruitment strategies for the detection of individuals at clinical high risk of developing psychosis
Addington, J., McGregor, L. S., Marulanda, D., & Raedler, T. J. (2012) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796012000583 · Cited by 13
Self-citation
Association between rostral prefrontal cortical activity and functional outcome in first-episode psychosis: a longitudinal functional near-infrared spectroscopy study
Koike, S., Satomura, Y., Kawasaki, S., Nishimura, Y., Takano, Y., Iwashiro, N., Kinoshita, A., Nagai, T., Natsubori, T., Tada, M., et al. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.01.003 · Cited by 13
Psychosocial functioning in adolescent patients assessed with Children's Global Assessment Scale (CGAS) predicts negative outcomes from age 18: A cohort study
Lundh, A., Forsman, M., Serlachius, E., Långström, N., Lichtenstein, P., & Landén, M. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.04.050 · Cited by 13

Authors: Cannon, T. D., Cadenhead, K., Cornblatt, B., Woods, S. W., Addington, J., Walker, E., Seidman, L. J., Perkins, D., Tsuang, M., McGlashan, T., & Heinssen, R.
Affiliations: University of California, Los Angeles (US)
University of California San Diego (US)
Zucker Hillside Hospital (US)
Yale University (US)
University of Toronto (CA)
Emory University (US)
Harvard University (US)
University of North Carolina at Chapel Hill (US)
National Institute of Mental Health (US)
ORCID: Cannon, Tyrone D.
Cadenhead, Kristin
Cornblatt, Barbara
Woods, Scott W.
Addington, Jean
Walker, Elaine
Seidman, Larry J.
Perkins, Diana
Tsuang, Ming
McGlashan, Thomas
Venue: Archives of General Psychiatry
Publisher: American Medical Association (AMA)
Published: 2008-01-01
Volume: 65
Issue: 1
Pages: 28
ISSN: 0003-990X (ISSN-L)
DOI: 10.1001/archgenpsychiatry.2007.3
PMC: PMC3065347
OpenAlex: W2140824803
Cited by: 1,269
References: 68
Citations by year: 2026: 14 · 2025: 22 · 2024: 19 · 2023: 30 · 2022: 32 · 2021: 52 · 2020: 51 · 2019: 72 · 2018: 50 · 2017: 80 · 2016: 91 · 2015: 98 · 2014: 93 · 2013: 115 · 2012: 109
FWCI: 78.94
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Archives of General Psychiatry (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (UL1TR000454)
National Institute of Mental Health (K24MH076191, K23MH001905, U01MH082022, R01MH060720, U01MH082004, U01MH081944)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords: psychosis prediction, clinical high risk for psychosis, schizophrenia, transition to psychosis, risk prediction algorithm, unusual thought content, social dysfunction, substance abuse, North American Prodrome Longitudinal Study
MeSH terms: Adolescent, Adult, Algorithms, Cognition, Female, Humans, Longitudinal Studies, Male, Paranoid Disorders, Predictive Value of Tests, Prognosis, Psychotic Disorders, Risk Factors, Schizophrenia, Social Behavior, Syndrome, Antipsychotic Agents, Substance-Related Disorders, Genetic Predisposition to Disease, Kaplan-Meier Estimate

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Prediction of Psychosis in Youth at High Clinical Risk: A Multisite Longitudinal Study in North America

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks