The DOI matches its Crossref record; 40 of the 41 references it cites were found in a registry or an index.
Prevalence and Correlates of Bipolar Spectrum Disorder in the World Mental Health Survey Initiative
Open accessAbstract
CONTEXT: There is limited information on the prevalence and correlates of bipolar spectrum disorder in international population-based studies using common methods. OBJECTIVES: To describe the prevalence, impact, patterns of comorbidity, and patterns of service utilization for bipolar spectrum disorder (BPS) in the World Health Organization World Mental Health Survey Initiative. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional, face-to-face, household surveys of 61,392 community adults in 11 countries in the Americas, Europe, and Asia assessed with the World Mental Health version of the World Health Organization Composite International Diagnostic Interview, version 3.0, a fully structured, lay-administered psychiatric diagnostic interview. MAIN OUTCOME MEASURES: Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) disorders, severity, and treatment. RESULTS: The aggregate lifetime prevalences were 0.6% for bipolar type I disorder (BP-I), 0.4% for BP-II, 1.4% for subthreshold BP, and 2.4% for BPS. Twelve-month prevalences were 0.4% for BP-I, 0.3% for BP-II, 0.8% for subthreshold BP, and 1.5% for BPS. Severity of both manic and depressive symptoms as well as suicidal behavior increased monotonically from subthreshold BP to BP-I. By contrast, role impairment was similar across BP subtypes. Symptom severity was greater for depressive episodes than manic episodes, with approximately 74.0% of respondents with depression and 50.9% of respondents with mania reporting severe role impairment. Three-quarters of those with BPS met criteria for at least 1 other disorder, with anxiety disorders (particularly panic attacks) being the most common comorbid condition. Less than half of those with lifetime BPS received mental health treatment, particularly in low-income countries, where only 25.2% reported contact with the mental health system. CONCLUSIONS: Despite cross-site variation in the prevalence rates of BPS, the severity, impact, and patterns of comorbidity were remarkably similar internationally. The uniform increases in clinical correlates, suicidal behavior, and comorbidity across each diagnostic category provide evidence for the validity of the concept of BPS. Treatment needs for BPS are often unmet, particularly in low-income countries.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“While the prevalence rates for each subtype varied across the nine countries studied, subthreshold BD was the most common at 1.4% (0.8%), followed by BDI at 0.6% (0.4%) and BDII at 0.4% (0.3%).6”
From Canadian Network for Mood and Anxiety Treatments ( CANMAT ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder (2018) · cites this paper as [6]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Worldwide, approximately 43% of patients with BD report suicidal ideation, 21% a plan, and 16% a suicide attempt within the past year.6”
From Canadian Network for Mood and Anxiety Treatments ( CANMAT ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder (2018) · cites this paper as [6]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“The World Mental Health Survey Initiative reported total lifetime (and 12‐month) prevalence estimates of 2.4% (1.5%) across BDI, BDII and subthreshold BD subtypes.”
The check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Worldwide, approximately 43% of patients with BD report suicidal ideation, 21% a plan, and 16% a suicide attempt within the past year.6”
From Canadian Network for Mood and Anxiety Treatments ( CANMAT ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder (2018) · cites this paper as [6]
Experimental — accuracy not yet measuredThe check wasn’t confident either way, so it gives no verdict — never disputed.
In the citing paper
“Worldwide, approximately 43% of patients with BD report suicidal ideation, 21% a plan, and 16% a suicide attempt within the past year.6”
From Canadian Network for Mood and Anxiety Treatments ( CANMAT ) and International Society for Bipolar Disorders ( ISBD ) 2018 guidelines for the management of patients with bipolar disorder (2018) · cites this paper as [6]
Experimental — accuracy not yet measured
In the citing paper
“bipolar depression is considerably more persistent than non-bipolar depression,5”
From The Costs of Depression (2012) · cites this paper as [5]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Rating Scale for Mania: Reliability, Validity and Sensitivity
Young, R. C., Biggs, J. T., Ziegler, V. E., & Meyer, D. A. (1978) · British Journal of Psychiatry · doi:10.1192/bjp.133.5.429 · Cited by 8,744
The World Health Report 2002 - Reducing Risks, Promoting Healthy Life
Available, N. A. N. (2003) · Education for Health · doi:10.1080/1357628031000116808 · Cited by 6,078
Rush, A. J., Trivedi, M. H., Ibrahim, H. M., Carmody, T. J., Arnow, B., Klein, D. N., Markowitz, J. C., Ninan, P. T., Kornstein, S., Manber, R., et al. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01866-8 · Cited by 3,829
Davenport, Y. B., Adland, M. L., Gold, P. W., & Goodwin, F. K. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92810-1 · Cited by 2,925
Merikangas, K. R., Akiskal, H. S., Angst, J., Greenberg, P. E., Hirschfeld, R. M. A., Petukhova, M., & Kessler, R. C. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.5.543 · Cited by 2,399
Self-citationCross-national epidemiology of major depression and bipolar disorder
Weissman, M. M. (1996) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1996.03540040037030 · Cited by 2,302
Introduction to Variance Estimation.
King, B. F., & Wolter, K. M. (1987) · Journal of the American Statistical Association · doi:10.2307/2289497 · Cited by 1,377
Prevalence and incidence studies of anxiety disorders: A systematic review of the literature
Somers, J. M., Goldner, E. M., Waraich, P., & Hsu, L. (2006) · The Canadian Journal of Psychiatry · doi:10.1177/070674370605100206 · Cited by 1,114
Assessing Psychiatric Impairment in Primary Care with the Sheehan Disability Scale
Leon, A. C., Olfson, M., Portera, L., Farber, L., & Sheehan, D. V. (1997) · The International Journal of Psychiatry in Medicine · doi:10.2190/t8em-c8yh-373n-1uwd · Cited by 987
Angst, J., Gamma, A., Benazzi, F., Ajdacic‐Gross, V., Eich, D., & Wulf Rössler, A. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00322-1 · Cited by 889
Research works printed but not linked: 4
- [8]Bauer M Pfennig A Epidemiology of bipolar disorders Epilepsia 2005 46 Suppl 4 8 13 15968806
- [12]Pini S de Queiroz V Pagnin D Prevalence and burden of bipolar disorders in European countries Eur Neuropsychopharmacol 2005 8 15 4 425 434 15935623
- [13]Cooper JE Kendell RE Gurland B Sharpe L Copeland JRM Simon R Psychiatric diagnosis in New York and London: A comparative study of mental hospital admissions 1972 London Oxford University Press
- [26]First M Spitzer R Gibbon M Williams J Structured Clinical Interview for DSM-IV Axis I Disorders, Research Version, Non-patient Edition (SCID-I/NP) 2002 New York Biometrics Research, New York State Psychatric Institute
Cited by
Sorted by citations
Items 101–200 of 1,006
The bipolarity of light and dark: A review on Bipolar Disorder and circadian cycles
Abreu, T., & Bragança, M. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.07.017 · Cited by 136
Nesvåg, R., Knudsen, G. P., Bakken, I. J., Høye, A., Ystrøm, E., Surén, P., Reneflot, A., Stoltenberg, C., & Reichborn‐Kjennerud, T. (2015) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-015-1025-2 · Cited by 137
Asherson, P. J., Young, A. H., Eich‐Höchli, D., Moran, P., Porsdal, V., & Deberdt, W. G. (2014) · Current Medical Research and Opinion · doi:10.1185/03007995.2014.915800 · Cited by 140
Amare, A. T., Schubert, K. O., & Baune, B. T. (2017) · The EPMA Journal · doi:10.1007/s13167-017-0112-8 · Cited by 132
Actigraphic features of bipolar disorder: A systematic review and meta-analysis
De Crescenzo, F., Economou, A., Sharpley, A. L., Gormez, A., & Quested, D. J. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.05.003 · Cited by 128
He, H., Hu, C., Ren, Z., Bai, L., Gao, F., & Lyu, J. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.03.015 · Cited by 135
Self-citationAbé, C., Ekman, C. J., Sellgren, C. M., Petrović, P., Ingvar, M., & Landén, M. (2015) · Brain · doi:10.1093/brain/awv266 · Cited by 128
Bipolar disorder in pregnancy and childbirth: a systematic review of outcomes
Rusner, M., Berg, M., & Begley, C. (2016) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-016-1127-1 · Cited by 133
Carrà, G., Bartoli, F., Crocamo, C., Brady, K. T., & Clerici, M. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.05.066 · Cited by 134
Lithium during pregnancy and after delivery: a review
Poels, E. M. P., Bijma, H. H., Galbally, M., & Bergink, V. (2018) · International Journal of Bipolar Disorders · doi:10.1186/s40345-018-0135-7 · Cited by 125
Comorbidity of bipolar and anxiety disorders: An overview of trends in research
Spoorthy, M. S., Chakrabarti, S., & Grover, S. (2018) · World Journal of Psychiatry · doi:10.5498/wjp.v9.i1.7 · Cited by 129
VGF as a biomarker and therapeutic target in neurodegenerative and psychiatric diseases
Quinn, J. P., Kandigian, S. E., Trombetta, B. A., Arnold, S. E., & Carlyle, B. C. (2021) · Brain Communications · doi:10.1093/braincomms/fcab261 · Cited by 124
Clinical practice guidelines for management of bipolar disorder
Shah, N., Grover, S., & Rao, G. (2017) · Indian Journal of Psychiatry · doi:10.4103/0019-5545.196974 · Cited by 124
Childhood trauma in bipolar disorder
Watson, S., Gallagher, P., Dougall, D., Porter, R., Moncrieff, J., Ferrier, I. N., & Young, A. H. (2014) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867413516681 · Cited by 122
Antecedents and sex/gender differences in youth suicidal behavior
Rhodes, A. E. (2014) · World Journal of Psychiatry · doi:10.5498/wjp.v4.i4.120 · Cited by 124
Lindström, L., Lindström, E., Nilsson, M., & Höistad, M. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.02.012 · Cited by 122
Omics-Based Biomarkers: Application of Metabolomics in Neuropsychiatric Disorders
Sethi, S., & Brietzke, E. M. (2015) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv096 · Cited by 125
Jiménez‐Fernández, S., Gurpegui, M., Rojas, D. G., Gutiérrez-Rojas, L., Carretero, M. D., & Correll, C. U. (2020) · Bipolar Disorders · doi:10.1111/bdi.12980 · Cited by 124
Lithium Treatment Over the Lifespan in Bipolar Disorders
Volkmann, C., Bschor, T., & Köhler, S. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00377 · Cited by 126
Postmortem evidence of brain inflammatory markers in bipolar disorder: a systematic review
Giridharan, V. V., Sayana, P., Pinjari, O. F., Ahmad, N., da Rosa, M. I., Quevedo, J., & Barichello, T. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0448-7 · Cited by 120
Mediators of allostasis and systemic toxicity in bipolar disorder
Grande, I., Magalhães, P. V. D. S., Kunz, M., Vieta, E., & Kapczinski, F. P. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.10.029 · Cited by 119
Molecular Mechanisms of Bipolar Disorder: Progress Made and Future Challenges
Kim, Y., Santos, R., Gage, F. H., & Marchetto, M. C. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00030 · Cited by 127
Emerging Evidence for the Widespread Role of Glutamatergic Dysfunction in Neuropsychiatric Diseases
McGrath, T., Baskerville, R., Rogero, M. M., & Castell, L. M. (2022) · Nutrients · doi:10.3390/nu14050917 · Cited by 124
Clinical risk factors for bipolar disorders: A systematic review of prospective studies
Faedda, G. L., Serra, G., Marangoni, C., Salvatore, P., Sani, G., Vázquez, G. H., Tondo, L., Girardi, P., Baldessarini, R. J., & Koukopoulos, A. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.07.013 · Cited by 122
McCarthy, M. J., Wei, H., Nievergelt, C. M., Stautland, A., Maihofer, A. X., Welsh, D. K., Shilling, P. D., Alda, M., Alliey‐Rodriguez, N., Anand, A., et al. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0273-8 · Cited by 112
Racial disparities in bipolar disorder treatment and research: a call to action
Akinhanmi, M. O., Biernacka, J. M., Strakowski, S. M., McElroy, S. L., Berry, J. E. B., Merikangas, K. R., Assari, S., McInnis, M. G., Schulze, T. G., Leboyer, M., et al. (2018) · Bipolar Disorders · doi:10.1111/bdi.12638 · Cited by 113
Self-citationKaur, P., & Sharma, M. (2019) · Journal of Medical Systems · doi:10.1007/s10916-019-1341-2 · Cited by 119
Genetic contributions to bipolar disorder: current status and future directions
O’Connell, K. S., & Coombes, B. J. (2021) · Psychological Medicine · doi:10.1017/s0033291721001252 · Cited by 122
The Risk of Treatment-Emergent Mania With Methylphenidate in Bipolar Disorder
Viktorin, A., Rydén, E., Thase, M. E., Chang, Z., Lundholm, C., D'Onofrio, B. M., Almqvist, C., Magnusson, P. K. E., Lichtenstein, P., Larsson, H., et al. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16040467 · Cited by 117
Song, J. H. T., Lowe, C. B., & Kingsley, D. M. (2018) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2018.07.011 · Cited by 112
Fries, G. R., Zamzow, M. J., Andrews, T., Pink, O., Scaini, G., & Quevedo, J. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.01.035 · Cited by 114
Comorbidity in pediatric bipolar disorder: Prevalence, clinical impact, etiology and treatment
Frías, Á., Palma, C., & Farriols, N. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.12.008 · Cited by 115
Bipolar disorder: Trimodal age‐at‐onset distribution
Bolton, S., Warner, J., Harriss, E., Geddes, J. R., & Saunders, K. E. A. (2020) · Bipolar Disorders · doi:10.1111/bdi.13016 · Cited by 115
The structure of common and uncommon mental disorders
Forbush, K. T., & Watson, D. (2013) · Psychological Medicine · doi:10.1017/s0033291712001092 · Cited by 109
Gildengers, A. G., Butters, M. A., Aizenstein, H. J., Marron, M. M., Emanuel, J. E., Anderson, S., Weissfeld, L. A., Becker, J. T., López, O. L., Mulsant, B. H., et al. (2014) · Bipolar Disorders · doi:10.1111/bdi.12260 · Cited by 110
An evidence map of psychosocial interventions for the earliest stages of bipolar disorder
Vallarino, M., Henry, C., Étain, B., Gehue, L. J., Macneil, C. A., Scott, E. M., Barbato, A., Conus, P., Hlastala, S. A., Fristad, M. A., et al. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(15)00156-x · Cited by 113
Animal models for bipolar disorder: from bedside to the cage
Beyer, D. K. E., & Freund, N. (2017) · International Journal of Bipolar Disorders · doi:10.1186/s40345-017-0104-6 · Cited by 113
Biomarkers for major depressive and bipolar disorders using metabolomics: A systematic review
MacDonald, K., Krishnan, A., Cervenka, E., Hu, G., Guadagno, E., & Trakadis, Y. J. (2018) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32680 · Cited by 108
A population-based heritability estimate of bipolar disorder – In a Swedish twin sample
Johansson, V., Kuja‐Halkola, R., Cannon, T. D., Hultman, C. M., & Hedman, A. M. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.06.010 · Cited by 116
The catecholaminergic–cholinergic balance hypothesis of bipolar disorder revisited
van Enkhuizen, J., Janowsky, D. S., Olivier, B., Minassian, A., Perry, W., Young, J. W., & Geyer, M. A. (2014) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2014.05.063 · Cited by 111
Evolutionary theories of depression: a critical review
Hagen, E. H. (2011) · The Canadian Journal of Psychiatry · doi:10.1177/070674371105601203 · Cited by 105
Vázquez, G. H., Holtzman, J. N., Lolich, M., Ketter, T. A., & Baldessarini, R. J. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.07.013 · Cited by 102
Caseras, X., Murphy, K., Lawrence, N., Fuentes‐Claramonte, P., Watts, J., Jones, D. K., & Phillips, M. L. (2015) · Bipolar Disorders · doi:10.1111/bdi.12292 · Cited by 105
An update on the debated association between ADHD and bipolar disorder across the lifespan
Skirrow, C., Hosang, G. M., FARMER, A. E., & Asherson, P. J. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.04.003 · Cited by 112
Saccaro, L. F., Schilliger, Z., Dayer, A. G., Perroud, N. A., & Piguet, C. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.04.017 · Cited by 109
Abé, C., Ching, C. R. K., Liberg, B., Lebedev, A. V., Agartz, I., Akudjedu, T. N., Alda, M., Alnæs, D., Alonso-Lana, S., Benedetti, F., et al. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.09.008 · Cited by 103
Wei, Y., Wang, T., Li, G., Feng, J., Deng, L., Xu, H., Yin, L., Ma, J., Chen, D., & Chen, J. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.941728 · Cited by 99
Kim, Y., & Na, K. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.06.024 · Cited by 106
Monocyte and microglial activation in patients with mood-stabilized bipolar disorder
Jakobsson, J., Bjerke, M., Sahebi, S., Isgren, A., Ekman, C. J., Sellgren, C. M., Olsson, B., Zetterberg, H., Blennow, K., Pålsson, E., et al. (2015) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.140183 · Cited by 99
Chemokine alterations in bipolar disorder: A systematic review and meta-analysis
Misiak, B., Bartoli, F., Carrà, G., Małecka, M., Samochowiec, J., Jarosz, K., Banik, A., & Stańczykiewicz, B. (2020) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2020.04.013 · Cited by 102
Yoshimi, N., Futamura, T., Kakumoto, K., Salehi, A. M., Sellgren, C. M., Holmén‐Larsson, J., Jakobsson, J., Pålsson, E., Landén, M., & Hashimoto, K. (2016) · BBA Clinical · doi:10.1016/j.bbacli.2016.03.008 · Cited by 100
Ketamine and other glutamate receptor modulators for depression in bipolar disorder in adults
McCloud, T. L., Caddy, C., Jochim, J., Rendell, J. M., Diamond, P. R., Shuttleworth, C., Brett, D., Amit, B. H., McShane, R., Hamadi, L., et al. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011611.pub2 · Cited by 102
Hidalgo-Mazzei, D., Mateu, A., Reinares, M., Matic, A., Vieta, E., & Colom, F. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.08.005 · Cited by 92
Hulvershorn, L. A., Karne, H. S., Gunn, A. D., Hartwick, S. L., Wang, Y., Hummer, T. A., & Anand, A. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.10.038 · Cited by 102
Rapid Mood-Elevating Effects of Low Field Magnetic Stimulation in Depression
Rohan, M. L., Yamamoto, R. T., Ravichandran, C. T., Cayetano, K. R., Morales, O. G., Olson, D. P., Vitaliano, G., Paul, S. M., & Cohen, B. M. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.10.024 · Cited by 97
Bipolar disorder: An evolutionary psychoneuroimmunological approach
Rantala, M. J., Luoto, S., Borráz-León, J. I., & Krams, I. A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.12.031 · Cited by 104
Jaeschke, K. N., Hanna, F., Ali, S., Chowdhary, N., Dua, T., & Charlson, F. (2021) · Cambridge Prisms Global Mental Health · doi:10.1017/gmh.2021.19 · Cited by 102
Miklowitz, D. J., Schneck, C. D., George, E. L., Taylor, D. O., Sugar, C. A., Birmaher, B. B., Kowatch, R. A., DelBello, M. P., & Axelson, D. (2014) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.13081130 · Cited by 96
Inflammation in Bipolar Disorder (BD): Identification of new therapeutic targets
Pereira, A. C., Oliveira, J. M., Silva, S., Madeira, N. G. G. F., Pereira, C., & Cruz, M. T. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105325 · Cited by 101
Singh, B., Swartz, H. A., Barboza, A. B. C., Schaffer, A., Kato, T., Dols, A., Sperry, S. H., Vassilev, A. B., Burdick, K. E., & Frye, M. A. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01140-7 · Cited by 106
Offidani, E., Fava, G. A., Tomba, E., & Baldessarini, R. J. (2013) · Psychotherapy and Psychosomatics · doi:10.1159/000345316 · Cited by 94
Prevalence of mental disorders and mental health service use in Japan
Nishi, D., Ishikawa, H., & Kawakami, N. (2019) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12894 · Cited by 102
Predominant polarity as a course specifier for bipolar disorder: A systematic review
Carvalho, A. F., McIntyre, R. S., Dimellis, D., Gonda, X., Berk, M., Nunes-Neto, P. R., Cha, D. S., Hyphantis, T. N., Angst, J., & Fountoulakis, K. Ν. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.03.035 · Cited by 95
Holmes, E. A., Bonsall, M. B., Hales, S. A., Mitchell, H., Renner, F., Blackwell, S. E., Watson, P., Goodwin, G. M., & Simplicio, M. C. D. (2016) · Translational Psychiatry · doi:10.1038/tp.2015.207 · Cited by 100
CO-OCCURRENCE OF ANXIETY AND BIPOLAR DISORDERS: CLINICAL AND THERAPEUTIC OVERVIEW
Vázquez, G. H., Baldessarini, R. J., & Tondo, L. (2014) · Depression and Anxiety · doi:10.1002/da.22248 · Cited by 94
de Barros, J. L. V. M., Barbosa, I. G., Salem, H., Rocha, N. P., Kümmer, A., Okusaga, O. O., Soares, J. C., & Teixeira, A. L. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.11.016 · Cited by 93
Hidalgo‐Mazzei, D., Reinares, M., Mateu, A., Nikolova, V. L., Bonnín, C. D. M., Samalin, L., García-Estela, A., Pérez, V., Young, A. H., Strejilevich, S., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.08.048 · Cited by 92
Jakobsson, J., Bjerke, M., Ekman, C. J., Sellgren, C. M., Johansson, A. G. M., Zetterberg, H., Blennow, K., & Landén, M. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.81 · Cited by 91
Functional outcome assessment in bipolar disorder: A systematic literature review
Chen, M., Fitzgerald, H. M., Madera‐McDonough, J., & Tohen, M. F. (2019) · Bipolar Disorders · doi:10.1111/bdi.12775 · Cited by 90
Ramírez‐Martín, A., Ramos-Martín, J., Mayoral, F., Moreno‐Küstner, B., & Parra, J. G. (2020) · Psychological Medicine · doi:10.1017/s0033291720003086 · Cited by 91
Suicide Risk Factors and Risk Assessment Tools: A Systematic Review
Haney, E. M., O'Neil, M. E., Carson, S., Low, A., Peterson, K., Denneson, L. M., Oleksiewicz, C., & Kansagara, D. L. (2012) · Europe PMC (PubMed Central) · Cited by 89
Immune-based strategies for mood disorders: facts and challenges
Colpo, G. D., Leboyer, M., Dantzer, R., Trivedi, M. H., & Teixeira, A. L. (2017) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2018.1407242 · Cited by 93
Characteristics of bipolar I and II disorder: A study of 8766 individuals
Karanti, A., Kardell, M., Joas, E., Runeson, B., Pålsson, E., & Landén, M. (2019) · Bipolar Disorders · doi:10.1111/bdi.12867 · Cited by 87
Childhood anxiety: An early predictor of mood disorders in offspring of bipolar parents
Duffy, A. C., Horrocks, J., Doucette, S., Keown‐Stoneman, C. D. G., McCloskey, S. M., & Grof, P. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.04.021 · Cited by 87
Prevalence of psychopathology in bipolar high-risk offspring and siblings: a meta-analysis
Lau, P., Hawes, D. J., Hunt, C. J., Frankland, A., Roberts, G. M. P., & Mitchell, P. B. (2017) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-017-1050-7 · Cited by 87
Cognitive Impairment in Patients with Bipolar Disorder: Impact of Pharmacological Treatment
Xu, N., Huggon, B., & Saunders, K. E. A. (2019) · CNS Drugs · doi:10.1007/s40263-019-00688-2 · Cited by 87
The mental health of university students in South Africa: Results of the national student survey
Bantjes, J. R., Kessler, M., Löchner, C., Breet, E., Bawa, A. C., Roos, J., Davids, C., Muturiki, M., Kessler, R. C., & Stein, D. J. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.10.044 · Cited by 86
Self-citationGoes, F. S. (2016) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2015.10.004 · Cited by 87
Spielberg, J. M., Beall, E. B., Hulvershorn, L. A., Altinay, M. I., Karne, H. S., & Anand, A. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2016.112 · Cited by 84
Dissecting bipolar disorder complexity through epigenomic approach
Ludwig, B., & Dwivedi, Y. (2016) · Molecular Psychiatry · doi:10.1038/mp.2016.123 · Cited by 88
Keramatian, K., Chithra, N. K., & Yatham, L. N. (2023) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.20230009 · Cited by 109
Pinto, J. V., Medeiros, L. S., da Rosa, G. S., de Oliveira, C. E. S., Crippa, J. A. S., Passos, I. C., & Kauer‐Sant’Anna, M. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.04.004 · Cited by 83
Circulating exosomal microRNAs in bipolar disorder
Ceylan, D., Tüfekçi, K. U., Keskinoğlu, P., Genç, Ş., & Özerdem, A. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.10.038 · Cited by 85
Gender differences in the treatment of patients with bipolar disorder: A study of 7354 patients
Karanti, A., Bobeck, C., Osterman, M., Kardell, M., Tidemalm, D., Runeson, B., Lichtenstein, P., & Landén, M. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.11.058 · Cited by 84
Public health significance of bipolar disorder: implications for early intervention and prevention
Conus, P., Macneil, C. A., & McGorry, P. D. (2013) · Bipolar Disorders · doi:10.1111/bdi.12137 · Cited by 84
Lithium: a versatile tool for understanding renal physiology
Kishore, B. K., & ECELBARGER, C. A. (2013) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00718.2012 · Cited by 84
Scaini, G., Fries, G. R., Valvassori, S. S., Zeni, C., Zunta‐Soares, G. B., Berk, M., Soares, J. C., & Quevedo, J. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.83 · Cited by 88
Pfaffenseller, B., Wollenhaupt-Aguiar, B., Fries, G. R., Colpo, G. D., Burque, R. K., Bristot, G., Ferrari, P., Ceresér, K. M. M., Rosa, A. R., Klamt, F., et al. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145714000443 · Cited by 84
Luo, Y., He, H., Zhang, M., Huang, X., & Fan, N. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.07.027 · Cited by 83
Joyce, K., Thompson, A. D., & Marwaha, S. (2016) · International Journal of Bipolar Disorders · doi:10.1186/s40345-016-0060-6 · Cited by 83
Steardo, L., Luciano, M., Sampogna, G., Zinno, F., Saviano, P., Staltari, F., Segura Garcia, C., De Fazio, P., & Fiorillo, A. (2020) · Annals of General Psychiatry · doi:10.1186/s12991-020-00266-7 · Cited by 81
Kovács, Z., D’Agostino, D. P., Diamond, D. M., Kindy, M. S., Rogers, C. Q., & Ari, C. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00363 · Cited by 87
Chen, J., Liu, Z., Fan, S., Yang, D., Zheng, P., Shao, W., Qi, Z.-G., Xu, X., Li, Q., Mu, J., et al. (2014) · Scientific Reports · doi:10.1038/srep05855 · Cited by 81
Jakobsson, J., Zetterberg, H., Blennow, K., Ekman, C. J., Johansson, A. G. M., & Landén, M. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.231 · Cited by 83
Triggers for Violent Criminality in Patients With Psychotic Disorders
Sariaslan, A., Lichtenstein, P., Larsson, H., & Fazel, S. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.1349 · Cited by 83
Cognitive Disinhibition, Creativity, and Psychopathology
Carson, S. (2014) · Wiley eBooks · doi:10.1002/9781118367377.ch11 · Cited by 79
Andreazza, A. C., & Young, L. T. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000096 · Cited by 84
Decreased global methylation in patients with bipolar disorder who respond to lithium
Huzayyin, A. A. S., Andreazza, A. C., Turecki, G., Cruceanu, C., Rouleau, G. A., Alda, M., & Young, L. T. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713001569 · Cited by 80
Léda‐Rêgo, G., Bezerra‐Filho, S., & Miranda‐Scippa, Â. (2020) · Bipolar Disorders · doi:10.1111/bdi.12904 · Cited by 80
Living with bipolar disorder: the impact on patients, spouses, and their marital relationship.
Granek, L., Danan, D., Bersudsky, Y., & Osher, Y. (2016) · Bipolar Disorders · doi:10.1111/bdi.12370 · Cited by 86
Metadata
- Authors
- Merikangas, K. R., Jin, R., He, J.-P., Kessler, R. C., Lee, S., Sampson, N. A., Viana, M. C., Andrade, L. H., Hu, C., Karam, E. G., Ladea, M., Medina-Mora, M. E., Ono, Y., Posada-Villa, J., Sagar, R., Wells, J. E., & Zarkov, Z.
- Affiliations
- National Institute of Mental Health (US)
- Harvard University (US)
- Chinese University of Hong Kong (HK)
- Universidade de São Paulo (BR)
- Shenzhen KangNing Hospital (CN)
- University of Balamand (LB)
- Carol Davila University of Medicine and Pharmacy (RO)
- Keio University (JP)
- All India Institute of Medical Sciences (IN)
- ORCID
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2011-03-07
- Volume
- 68
- Issue
- 3
- Pages
- 241
- ISSN
- 0003-990X (ISSN-L)
- PMC
- PMC3486639
- OpenAlex
- W1984344128
- Cited by
- 2,627
- References
- 41
- Citations by year
- 2026: 135 · 2025: 212 · 2024: 191 · 2023: 190 · 2022: 232 · 2021: 231 · 2020: 210 · 2019: 219 · 2018: 173 · 2017: 179 · 2016: 162 · 2015: 142 · 2014: 126 · 2013: 111 · 2012: 80
- FWCI
- 76.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Archives of General Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Scientific Electronic Library Online (São Paulo Research Foundation, Latin American and Caribbean Center on Health Sciences Information, Conselho Nacional de Desenvolvimento Científico e Tecnológico) (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5r13mh066849-04, 5r01mh069864-04, 5r01mh070884-05)
- National Institute of Mental Health (R13-MH-066849, R01‐MH070884, U01-MH-60220, U01MH060220, R01‐MH069864)
- National Institute on Drug Abuse (K05DA015799, R01DA016558)
- Fogarty International Center (R03TW006481)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- bipolar spectrum disorders, bipolar I disorder, bipolar II disorder, prevalence, comorbidities, anxiety disorders, panic attacks, suicidal behavior, symptom severity, role impairment, mental health service utilization, treatment needs, low-income countries, cross-national comparison
- MeSH terms
- Adolescent, Adult, Bipolar Disorder, Cross-Sectional Studies, Cross-Cultural Comparison, Depressive Disorder, Major, Major Depressive Disorder, Female, Health Surveys, Humans, Male, Mental Health Services, Middle Aged, Sex Factors, Socioeconomic Factors, Suicide, Attempted, Utilization Review, World Health Organization, Comorbidity, Age of Onset, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
