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Systemic lupus erythematosus in the community. Incidence, prevalence, outcome, and first symptoms; the high prevalence in black women
Abstract
The incidence, prevalence, and outcome of systemic lupus erythematosus (SLE) were examined in a large, well-defined population for which extensive records of complete medical care are available. The prevalence was 1:1,969; in women aged 15 to 64 years, approximately 1:700; in black women 15 to 64, 1:245. Mortality was low: only five deaths among 70 patients in whom SLE was freshly diagnosed occurred during an eightyear period. The projected ten-year survival rate exceeds 90%. The prevalence of clinically important renal disease was only 11%. Previous estimates of the prevalence of renal disease in SLE have been based on skewed series. Several clinical patterns of SLE were discerned: least common was the violent, rapidly fatal one; most patients experienced a benign, chronic course or intermittently stuttering illness; some had only one or a few brief episodes of the disease.
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Cited by
Epidemiology and estimated population burden of selected autoimmune diseases in the United States
Jacobson, D. L., Gange, S. J., Rose, N. R., & Graham, N. M. H. (1997) · Clinical Immunology and Immunopathology · doi:10.1006/clin.1997.4412 · Cited by 1,667
D'Cruz, D. P., Khamashta, M. A., & Hughes, G. R. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60279-7 · Cited by 992
Rees, F., Doherty, M., Grainge, M. J., Lanyon, P., & Zhang, W. (2017) · Rheumatology · doi:10.1093/rheumatology/kex260 · Cited by 789
Autoimmunity after Alpha-Interferon Therapy for Malignant Carcinoid Tumors
Rönnblom, L. E., Alm, G. V., & Öberg, K. E. (1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-115-3-178 · Cited by 455
Sex differences in rheumatoid arthritis: more than meets the eye
van Vollenhoven, R. F. (2009) · BMC Medicine · doi:10.1186/1741-7015-7-12 · Cited by 326
Metadata
- Authors
- Wj, F.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association
- Published
- 1974-12-01
- Volume
- 134
- Issue
- 6
- Pages
- 1027-1035
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W4252546942
- Cited by
- 429
- References
- 0
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Systemic lupus erythematosus in the community. Incidence, prevalence, outcome, and first symptoms; the high prevalence in black women. https://app.cochat.ai/papers/10.1001/archinte.134.6.1027
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- Wj, F. (1974). Systemic lupus erythematosus in the community. Incidence, prevalence, outcome, and first symptoms; the high prevalence in black women. Archives of Internal Medicine. https://doi.org/10.1001/archinte.134.6.1027
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
