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Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. The Expert Panel
Abstract
This report of an expert panel of the National Cholesterol Education Program provides new guidelines for the treatment of high blood cholesterol in adults 20 years of age and over. Total cholesterol levels are classified as follows: less than 200 mg/dL--"desirable blood cholesterol"; 200 to 239 mg/dL--borderline-high blood cholesterol; greater than or equal to 240 mg/dL--high blood cholesterol. The guidelines detail which patients should go on to have lipoprotein analysis, and which should receive cholesterol-lowering treatment on the basis of their low density lipoprotein (LDL)-cholesterol levels and status with respect to other coronary heart disease risk factors. Dietary therapy is the primary cholesterol-lowering treatment. The report specifies the LDL-cholesterol levels at which dietary therapy should be started and the goals of therapy, and provides detailed guidance on the nature of the recommended dietary changes. If, after six months of intensive dietary therapy, LDL-cholesterol exceeds specified levels, drug treatment should be considered.
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Citations
Cited by
A prospective study of cholesterol, apolipoproteins, and the risk of myocardial infarction.
Stampfer, M. J., Sacks, F. M., Salvini, S., Willett, W. C., & Hennekens, C. H. (1991) · New England Journal of Medicine · doi:10.1056/nejm199108083250601 · Cited by 1,163
Pekkanen, J., Linn, S., Heiss, G., Suchindran, C. M., Leon, A., Rifkind, B. M., & Tyroler, H. A. (1990) · New England Journal of Medicine · doi:10.1056/nejm199006143222403 · Cited by 821
Self-citationStefanick, M. L., Mackey, S., Sheehan, M., Ellsworth, N., Haskell, W. L., & Wood, P. D. (1998) · New England Journal of Medicine · doi:10.1056/nejm199807023390103 · Cited by 629
Probucol and Multivitamins in the Prevention of Restenosis after Coronary Angioplasty
Tardif, J.-C., Côté, G., Lespérance, J., Bourassa, M., Lambert, J., Doucet, S., Bilodeau, L., Nattel, S., & de Guise, P. (1997) · New England Journal of Medicine · doi:10.1056/nejm199708073370601 · Cited by 565
The outcomes movement—Will it get us where we want to go?
Epstein, A. M. (1990) · New England Journal of Medicine · doi:10.1056/nejm199007263230410 · Cited by 371
Metadata
- Authors
- Goodman, D. S., Hulley, S. B., Clark, L. T., Davis, C. E., Fuster, V., LaRosa, J. C., Oberman, A., Schaefer, E. J., Steinberg, D., Brown, W. V., Grundy, S. M., Becker, D., Bierman, E., Sooter-Bochenek, J., Mullis, R., Stone, N., Hunninghake, D. B., Dunbar, J. M., Ginsberg, H. N., Illingworth, D. R., Sadin, H. C., Schonfeld, G., Cleeman, J. I., Brewer, H. B., Ernst, N., Friedewald, W., Hoeg, J. M., Rifkind, B., & Gordon, D.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1988-01-01
- Volume
- 148
- Issue
- 1
- Pages
- 36
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W4252142357
- Cited by
- 529
- References
- 0
- FWCI
- 59.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. The Expert Panel. https://app.cochat.ai/papers/10.1001/archinte.148.1.36
- The paper
- Goodman, D. S., Hulley, S. B., Clark, L. T., Davis, C. E., Fuster, V., LaRosa, J. C., Oberman, A., Schaefer, E. J., Steinberg, D., Brown, W. V., Grundy, S. M., Becker, D., Bierman, E., Sooter-Bochenek, J., Mullis, R., Stone, N., Hunninghake, D. B., Dunbar, J. M., Ginsberg, H. N., . . . Gordon, D. (1988). Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. The Expert Panel. Archives of Internal Medicine. https://doi.org/10.1001/archinte.148.1.36
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.