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The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

The Aneurysm Detection and Management Study Screening Program: Validation Cohort and Final Results

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Lederle, Frank A.·2000·Archives of Internal Medicine

Abstract

BACKGROUND: We previously reported the prevalence and associations of abdominal aortic aneurysm (AAA) in 73451 veterans aged 50 to 79 years who underwent ultrasound screening. OBJECTIVE: To understand the prevalence of and principal positive and negative risk factors for AAA, and to assess reproducibility of our previous findings. METHODS: In the new cohort of veterans undergoing screening, 52 745 subjects aged 50 to 79 without history of AAA underwent successful ultrasound screening for AAA, after completing a questionnaire on demographics and potential risk factors. RESULTS: We detected AAA of 4.0 cm or larger in 613 participants (1.2%; compared with 1.4% in the earlier cohort). The direction and magnitude of the important associations reported in the first cohort were confirmed. Respective odds ratios for the major associations with AAA for the second and for the combined cohorts were as follows: 1.81 and 1.71 for age (per 7 years), 0.12 and 0. 18 for female sex, 0.59 and 0.53 for black race, 1.94 and 1.94 for family history of AAA, 4.45 and 5.07 for smoking, 0.50 and 0.52 for diabetes, and 1.60 and 1.66 for atherosclerotic diseases. The excess prevalence associated with smoking accounted for 75% of all AAAs of 4.0 cm or larger in the total population of 126 196. Associations for AAA of 3.0 to 3.9 cm were similar but tended to be somewhat weaker. CONCLUSIONS: Our findings confirm our previous cohort findings. Age, smoking, family history of AAA, and atherosclerotic diseases remained the principal positive associations with AAA, and female sex, diabetes, and black race remained the principal negative associations.

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Metadata

Authors
Lederle, F. A.
Venue
Archives of Internal Medicine
Published
2000-05-22
Volume
160
Issue
10
Pages
1425
ISSN
0003-9926 (ISSN-L)
OpenAlex
W2100392330
Cited by
722
References
13
FWCI
10.59
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Aneurysm Detection and Management Study Screening Program: Validation Cohort and Final Results. https://app.cochat.ai/papers/10.1001/archinte.160.10.1425
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Lederle, F. A. (2000). The Aneurysm Detection and Management Study Screening Program: Validation Cohort and Final Results. Archives of Internal Medicine. https://doi.org/10.1001/archinte.160.10.1425

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