CoChat
Sign Up
Cited by 1,694Obesity, Physical Activity, DietDiabetes, Cardiovascular Risks, and LipoproteinsCancer Risks and Factors

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Impact of Overweight on the Risk of Developing Common Chronic Diseases During a 10-Year Period

Open access
Field, Alison E., Coakley, Eugenie H., Must, Aviva, Spadano, Jennifer L., Laird, Nan, Dietz, William H., Rimm, Eric, Colditz, Graham A.·2001·Archives of Internal Medicine
DOI 10.1001/archinte.161.13.1581
Open this paper in CoChat — free account

Abstract

BACKGROUND: Overweight adults are at an increased risk of developing numerous chronic diseases. METHODS: Ten-year follow-up (1986-1996) of middle-aged women in the Nurses' Health Study and men in the Health Professionals Follow-up Study to assess the health risks associated with overweight. RESULTS: The risk of developing diabetes, gallstones, hypertension, heart disease, and stroke increased with severity of overweight among both women and men. Compared with their same-sex peers with a body mass index (BMI) (calculated as weight in kilograms divided by the square of height in meters) between 18.5 and 24.9, those with BMI of 35.0 or more were approximately 20 times more likely to develop diabetes (relative risk [RR], 17.0; 95% confidence interval [CI], 14.2-20.5 for women; RR, 23.4; 95% CI, 19.4-33.2 for men). Women who were overweight but not obese (ie, BMI between 25.0 and 29.9) were also significantly more likely than their leaner peers to develop gallstones (RR, 1.9), hypertension (RR, 1.7), high cholesterol level (RR, 1.1), and heart disease (RR, 1.4). The results were similar in men. CONCLUSIONS: During 10 years of follow-up, the incidence of diabetes, gallstones, hypertension, heart disease, colon cancer, and stroke (men only) increased with degree of overweight in both men and women. Adults who were overweight but not obese (ie, 25.0 < or = BMI < or = 29.9) were at significantly increased risk of developing numerous health conditions. Moreover, the dose-response relationship between BMI and the risk of developing chronic diseases was evident even among adults in the upper half of the healthy weight range (ie, BMI of 22.0-24.9), suggesting that adults should try to maintain a BMI between 18.5 and 21.9 to minimize their risk of disease.

Overview

Integrity signals

Registry

Crossref · 10.1001/archinte.161.13.1581

Cites

41 of 41 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 40 references

Cited by

Sorted by citations

Items 701–800 of 999

Related

See all

Metadata

Authors
Field, A. E., Coakley, E. H., Must, A., Spadano, J. L., Laird, N., Dietz, W. H., Rimm, E., & Colditz, G. A.
Affiliations
  • Brigham and Women's Hospital (US)
  • John Snow (United States) (US)
  • Tufts University (US)
  • Harvard University (US)
  • Centers for Disease Control and Prevention (US)
ORCID
Venue
Archives of Internal Medicine
Publisher
American Medical Association (AMA)
Published
2001-07-09
Volume
161
Issue
13
Pages
1581
ISSN
0003-9926 (ISSN-L)
DOI
10.1001/archinte.161.13.1581
OpenAlex
W2145279264
Cited by
1,694
References
40
Citations by year
2026: 30 · 2025: 44 · 2024: 51 · 2023: 54 · 2022: 71 · 2021: 53 · 2020: 62 · 2019: 68 · 2018: 61 · 2017: 73 · 2016: 75 · 2015: 78 · 2014: 99 · 2013: 87 · 2012: 101
FWCI
41.66
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Archives of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Access to Scholarship at Harvard (DASH) (Harvard University) (submittedVersion, cc-by)
Funders
  • National Institutes of Health (46200, DK46200, CA40356, CA55075)
  • National Heart, Lung, and Blood Institute (R01HL035464, HL35464)
  • National Cancer Institute (CA-55075, CA-40356)
  • National Institute of Diabetes and Digestive and Kidney Diseases (P30DK046200, DK46200.)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Oncology › Cancer Risks and Factors
Keywords
overweight, obesity, body mass index, chronic disease risk, type 2 diabetes, gallstones, hypertension, heart disease, stroke, colon cancer, hypercholesterolemia, dose-response relationship, middle-aged adults, sex differences
MeSH terms
Cholelithiasis, Chronic Disease, Diabetes Mellitus, Female, Follow-Up Studies, Heart Diseases, Humans, Hypertension, Male, Middle Aged, Obesity, Risk Factors, Body Mass Index, Logistic Models

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review