The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Cognitive-Behavioral Therapy for Somatization Disorder: A Randomized Controlled Trial
Abstract
BACKGROUND: Patients diagnosed as having somatization disorder (SD) who present with a lifetime history of multiple, medically unexplained physical symptoms represent a significant challenge to health care providers. To date, no psychotherapeutic or pharmacologic intervention has been found to produce clinically meaningful improvement in symptoms or functioning of patients with SD. We examined the efficacy of cognitive-behavioral therapy (CBT) for SD. METHODS: Eighty-four participants meeting criteria for SD were randomly assigned to 1 of 2 conditions: (1) standard medical care augmented by a psychiatric consultation intervention or (2) a 10-session, manualized, individually administered CBT regimen added to the psychiatric consultation intervention. Assessments were conducted at baseline and 3, 9, and 15 months after baseline. The primary outcome measure was the severity scale of the Clinical Global Impression Scale for Somatization Disorder (CGI-SD). Secondary outcome measures were responder status as determined by clinical ratings, self-reported measures of physical functioning and somatic symptoms, and health care utilization assessed via medical records. RESULTS: Fifteen months after baseline, somatization symptoms were significantly less severe in the group treated with CBT (0.84 points on the CGI-SD 7-point scale) (P<.001). Patients treated with CBT also were significantly more likely to be rated as either very much improved or much improved than patients treated with only augmented standard medical care (40% [n = 17] vs 5% [n = 2]). Cognitive-behavioral therapy was associated with greater improvements in self-reported functioning and somatic symptoms and a greater decrease in health care costs. CONCLUSION: For patients diagnosed as having SD, CBT may produce clinical benefits beyond those that result from the current state-of-the-art treatment.
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“and reduced overall service use when offering individual CBT for somatisation disorder . 15”
From Cognitive behaviour therapy for long-term frequent attenders in primary care: A feasibility case series and treatment development study (2016) · cites this paper as [15]
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“This study sits among other studies demonstrating that service use can be reduced using CBT. 14-16”
From Cognitive behaviour therapy for long-term frequent attenders in primary care: A feasibility case series and treatment development study (2016) · cites this paper as [15]
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Cognitive Behavior Therapy for Hypochondriasis
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Bursch, B. (2010) · The Corsini Encyclopedia of Psychology · doi:10.1002/9780470479216.corpsy0927
(2006) · BMJ Evidence-Based Medicine · doi:10.1136/ebm.11.6.191
Michel, T. M., & Schneider, F. W. (2011) · Springer eBooks · doi:10.1007/978-3-642-17192-5_26
Kleinstäuber, M., Thomas, P., Witthöft, M., & Hiller, W. (2025) · Springer eBooks · doi:10.1007/978-3-662-69726-9_3
Romeo, A., Tella, M. D., Perutelli, V., Galli, F., Geminiani, G. C., & Castelli, L. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.11.034
Metadata
- Authors
- Allen, L. A., Woolfolk, R. L., Escobar, J. I., Gara, M. A., & Hamer, R. M.
- Affiliations
- University of Medicine and Dentistry of New Jersey (US)
- Rutgers, The State University of New Jersey (US)
- ORCID
- Escobar, Javier I.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2006-07-24
- Volume
- 166
- Issue
- 14
- Pages
- 1512
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2095986335
- Cited by
- 209
- References
- 18
- Citations by year
- 2025: 7 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 12 · 2018: 5 · 2017: 8 · 2016: 12 · 2015: 8 · 2014: 16 · 2013: 14 · 2012: 21
- FWCI
- 9.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5k08mh001662-03)
- National Institute of Mental Health (P20MH074634, K08 MH01662, R21MH066831)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
- Keywords
- somatization disorder, cognitive behavioral therapy, medically unexplained symptoms, psychiatric consultation, treatment efficacy, health care utilization, health care costs, physical function
- MeSH terms
- Adolescent, Adult, Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Severity of Illness Index, Somatoform Disorders, Cognitive Behavioral Therapy, Treatment Outcome
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