The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
STUDIES ON SERUM CHOLESTEROL AND OTHER CHARACTERISTICS OF CLINICALLY HEALTHY MEN IN NAPLES
Abstract
IN THE control of the concentration of blood cholesterol the diet clearly has a marked and ubiquitous effect, but the picture differs in various species. Man does not compare with the rabbit and the chick in sensitivity to exogenous cholesterol, but his response to total fats in the diet appears to be greater.* Obviously, quantitative information on the effect of the diet on the blood cholesterol level in man must be sought from man himself. Experiments on this problem in man generally have several defects. The studies reported so far have largely ignored the important factor of age7and have been limited to a few weeks or months of drastic change from previous lifelong subsistence on the relatively high-fat diet that is almost universally used in the United States at the present time. The present paper reports findings on clinically healthy men in Naples, where the habitual diet, like
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“Historically, in many but not all of the 22 countries bordering the Mediterranean Sea, a great abundance and diversity of nonstarchy vegetables, minimally processed whole-grain cereals, legumes, nuts, and seeds were staple foods for both men and women (Table 1).”
From Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms (2018) · cites this paper as [2]
In the citing paper
“Consistently the incidence of coronary heart disease and certain cancers, which was very low in those countries, has increased substantially (1,2,4).”
From Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms (2018) · cites this paper as [2]
In the citing paper
“For example, in Southern Italy in the 1950s, very little meat was eaten, typically only once every week or two, and milk was never used except in coffee (caffé macchiato) or for infants.”
From Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms (2018) · cites this paper as [2]
Citations
Cites
Keys, A. B., & Brožek, J. (1953) · Physiological Reviews · doi:10.1152/physrev.1953.33.3.245 · Cited by 855
THE CONCENTRATION OF CHOLESTEROL IN THE BLOOD SERUM OF NORMAL MAN AND ITS RELATION TO AGE 1
Keys, A., Mickelsen, O., Miller, E. V. O., Hayes, E. R., & Todd, R. L. (1950) · Journal of Clinical Investigation · doi:10.1172/jci102372 · Cited by 221
Atherosclerosis: a problem in newer public health.
Keys, A. (1953) · PubMed · Cited by 205
Analysis of the electrocardiograms obtained from 1000 young healthy aviators
Graybiel, A., McFarland, R. A., Gates, D. C., & Webster, F. A. (1944) · American Heart Journal · doi:10.1016/s0002-8703(44)90546-6 · Cited by 190
The Relation in Man between Cholesterol Levels in the Diet and in the Blood
Keys, A. B., Mickelsen, O., Miller, E. V. O., & Chapman, C. B. (1950) · Science · doi:10.1126/science.112.2899.79 · Cited by 190
Malmros, H. (1950) · PubMed · Cited by 106
EFFECT OF FEEDING EGG YOLK AND CHOLESTEROL ON SERUM CHOLESTEROL LEVELS
Messinger, W. J. (1950) · Archives of Internal Medicine · doi:10.1001/archinte.1950.00230140025004 · Cited by 85
Studies on the diet, body fatness and serum cholesterol in Madrid, Spain.
Keys, A. B., Vivanco, F., Minon, J.-M., Keys, M., & Mendoza, H. C. (1954) · PubMed · Cited by 77
Diet, Serum Cholesterol and Coronary Artery Disease
Gertler, M. M., Garn, S. M., & WHITE, P. D. (1950) · Circulation · doi:10.1161/01.cir.2.5.696 · Cited by 68
The Effect of Age and Body Weight on the Electrocardiogram of Healthy Men
Simonson, E., & Keys, A. B. (1952) · Circulation · doi:10.1161/01.cir.6.5.749 · Cited by 68
Cited by
Sorted by citations
ASSOCIATION OF SPECIFIC OVERT BEHAVIOR PATTERN WITH BLOOD AND CARDIOVASCULAR FINDINGS
Friedman, M. (1959) · JAMA · doi:10.1001/jama.1959.03000290012005 · Cited by 1,483
Health Benefits of the Mediterranean Diet: Metabolic and Molecular Mechanisms
Tosti, V., Bertozzi, B., & Fontana, L. (2018) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glx227 · Cited by 762
The effect of diet on plasma lipids, lipoproteins, and coronary heart disease
Kris‐Etherton, P. M., Krummel, D. A., Russell, M. E., Dreon, D. M., Mackey, S., Borchers, J., & Wood, P. D. (1988) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(21)08023-8 · Cited by 301
Mediterranean diets: historical and research overview
Nestle, M. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/61.6.1313s · Cited by 263
Coronary heart disease — The global picture
Keys, A. B. (1975) · Atherosclerosis · doi:10.1016/0021-9150(75)90001-5 · Cited by 246
Metadata
- Authors
- KEYS, A.
- Corresponding author
- KEYS, ANCEL
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1954-03-01
- Volume
- 93
- Issue
- 3
- Pages
- 328
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2064571916
- Cited by
- 109
- References
- 23
- Citations by year
- 2026: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 2 · 2016: 1 · 2014: 1 · 2013: 1
- FWCI
- 47.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Keywords
- serum cholesterol, dietary fat, healthy men, high-fat diet
- MeSH terms
- Blood, Cholesterol, Humans, Male, Men's Health
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