The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
A Model of Lifetime Osteoporosis Impact
Abstract
The study goal was to use population-based data to model aspects of lifetime osteoporosis impact not previously studied, specifically: (1) to estimate person-years of fracture-related functional impairment against the trajectory of functional status in the general population; (2) jointly to consider hip, vertebral, and Colles' fractures in estimating the percent of women who will ever fracture; and (3) to estimate the lifetime number of fractures expected in a cohort of 10,000 50-year-old white postmenopausal women. The model estimates that 54% of 50-year-old women will sustain osteoporosis-related fractures during their remaining lifetimes. Beyond the functional impairment expected in similarly aged, unfractured women, osteoporosis-related fractures are estimated to cause 6.7% of women to become dependent in basic activities of daily living; 7.8% are expected to require nursing home care for an average of 7.6 years.
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In the citing paper
“Levothyroxine was also associated with an increase in hip fractures specifically, which carry the greatest morbidity and mortality for older adults.55”
From Levothyroxine dose and risk of fractures in older adults: nested case-control study (2011) · cites this paper as [55]
Citations
Cites
Epidemiologic Research: Principles and Quantitative Methods.
Mayer, L. S., Kleinbaum, D. G., Kupper, L. L., & Morgenstern, H. (1984) · Journal of the American Statistical Association · doi:10.2307/2288427 · Cited by 2,905
EPIDEMIOLOGY OF OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES
Cummings, S. R., Kelsey, J. L., Nevitt, M. C., & O’Dowd, K. J. (1985) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a036281 · Cited by 1,701
The Markov process in medical prognosis
Beck, J. R., & Pauker, S. G. (1983) · Medical Decision Making · doi:10.1177/0272989x8300300403 · Cited by 957
EPIDEMIOLOGY OF VERTEBRAL FRACTURES IN WOMEN
Melton, L. J., Kan, S. H., Frye, M. A., Wahner, H. W., O’Fallon, W. M., & Riggs, B. L. (1989) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115204 · Cited by 922
Cummings, S. R. (1989) · Archives of Internal Medicine · doi:10.1001/archinte.1989.00390110045010 · Cited by 690
A Longitudinal Study of Functional Change and Mortality in the United States
Mantón, K. G. (1988) · Journal of Gerontology · doi:10.1093/geronj/43.5.s153 · Cited by 512
Established Populations for Epidemiologic Studies of the Elderly: Resource Data Book
Kaplan, G. A. (1987) · Journal of Gerontology · doi:10.1093/geronj/42.6.688a · Cited by 420
Relationship of Lung Function to Severity of Osteoporosis in Women
Leech, J. A., Dulberg, C. S., Kellie, S., Pattee, L., & Gay, J. (1990) · American Review of Respiratory Disease · doi:10.1164/ajrccm/141.1.68 · Cited by 402
Survival experience of aged hip fracture patients.
Magaziner, J. S., Simonsick, E. M., Kashner, T. M., Hebel, J. R., & Kenzora, J. E. (1989) · American Journal of Public Health · doi:10.2105/ajph.79.3.274 · Cited by 383
Survival and ambulation following hip fracture.
Miller, C. W. (1978) · Journal of Bone and Joint Surgery · doi:10.2106/00004623-197860070-00010 · Cited by 377
Cited by
Sorted by citations
Epidemiology and outcomes of osteoporotic fractures
Cummings, S. R., & Melton, L. J. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08657-9 · Cited by 3,821
Hip fractures in the elderly: A world-wide projection
Cooper, C. C., Campion, G., & Melton, L. J. (1992) · Osteoporosis International · doi:10.1007/bf01623184 · Cited by 3,225
“The lifetime risk of a hip fracture approaches 15% among 50-year-old white women [1,2], and the event has serious consequences including significant impairment of survival, a high prevalence of prolonged disability and an increased likelihood of institutionalization [ 2 ,3].”
BackgroundKanis, J. А., & Kanis, J. А. (1994) · Osteoporosis International · doi:10.1007/bf01622200 · Cited by 2,532
World-wide Projections for Hip Fracture
Gullberg, B., Johnell, O., & Kanis, J. А. (1997) · Osteoporosis International · doi:10.1007/pl00004148 · Cited by 2,300
“Approximately 50% of patients will have permanent functional disability greater than that before fracture [2, 3 ].”
BackgroundEffect of Risedronate on the Risk of Hip Fracture in Elderly Women
McClung, M. R., Geusens, P., Miller, P. D., Zippel, H., Bensen, W. G., Roux, C., Adami, S., Fogelman, I., Diamond, T., Eastell, R., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102013440503 · Cited by 1,918
Metadata
- Authors
- Chrischilles, E. A.
- Affiliations
- University of Iowa (US)
- Corresponding author
- Chrischilles, Elizabeth A.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1991-10-01
- Volume
- 151
- Issue
- 10
- Pages
- 2026
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2094251460
- Cited by
- 467
- References
- 36
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 5 · 2023: 12 · 2022: 2 · 2021: 6 · 2020: 9 · 2019: 11 · 2018: 12 · 2017: 11 · 2016: 11 · 2015: 10 · 2014: 13 · 2013: 15 · 2012: 15
- FWCI
- 8.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Surgery › Hip and Femur Fractures
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Keywords
- osteoporosis, hip fracture, vertebral fractures, Colles' fracture, functional disability, activities of daily living, nursing home care, postmenopausal women, fracture risk prediction model
- MeSH terms
- Colles' Fracture, Female, Fractures, Spontaneous, Health Status, Hip Fractures, Humans, Markov Chains, Mathematical Computing, Middle Aged, Prognosis, Recurrence, Models, Statistical, Cohort Studies, Osteoporosis, Postmenopausal, Spinal Fractures
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