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Etiology and Pathogenesis of Temporal Lobe Epilepsy

FALCONER, M. A., SERAFETINIDES, E. A., CORSELLIS, J. A. N.·1964·Archives of Neurology

Abstract

Increasing attention is being paid to the relationship of cerebral lesions to the epilepsies. Gastaut and Fischer-Williams27consider that cases of so-called functional or idiopathic epilepsy (which represent a fault in cerebral function rather than in structure) constitute only about 5% of cases and that most cases of epilepsy have underlying cerebral lesions. These lesions, however, may develop on a "soil" already predisposed to convulsions, which enables a mildly irritative lesion to become markedly epileptogenic. Gastaut24-26,28has also reviewed our present knowledge of the causes of temporal lobe epilepsy, which is a common form of focal or "partial" epilepsy.12,24,35,51However, this knowledge is still incomplete, and as Yakovlev66has pointed out, various lesions may be responsible. In this paper, therefore, we record the pathological findings in 100 consecutive patients with epilepsy submitted to a unilateral temporal lobectomy, and discuss their origin and their significance. Case

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Metadata

Authors
FALCONER, M. A., SERAFETINIDES, E. A., & CORSELLIS, J. A. N.
Venue
Archives of Neurology
Published
1964-03-01
Volume
10
Issue
3
Pages
233-248
ISSN
0003-9942 (ISSN-L)
OpenAlex
W2110074530
Cited by
664
References
13
FWCI
12.41
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Etiology and Pathogenesis of Temporal Lobe Epilepsy. https://app.cochat.ai/papers/10.1001/archneur.1964.00460150003001
The paper
FALCONER, M. A., SERAFETINIDES, E. A., & CORSELLIS, J. A. N. (1964). Etiology and Pathogenesis of Temporal Lobe Epilepsy. Archives of Neurology. https://doi.org/10.1001/archneur.1964.00460150003001

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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