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Cited by 455

The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.

Clinical Predictors of Quality of Life in Patients With Head and Neck Cancer

Terrell, Jeffrey E., Ronis, David L., Fowler, Karen E., Bradford, Carol R., Chepeha, Douglas B., Prince, Mark E., Teknos, Theodoros N., Wolf, Gregory T., Duffy, Sonia A.·2004·Archives of Otolaryngology–Head & Neck Surgery

Abstract

OBJECTIVE: To identify clinical predictors of quality of life (QoL) in a head and neck cancer patient population. DESIGN, PATIENTS, AND SETTING: A convenience sample of 570 patients with upper aerodigestive tract cancers were surveyed at a tertiary care oncology clinic and Veterans Affairs otolaryngology clinic. INTERVENTIONS: A self-administered health survey was constructed to collect demographic, health, smoking, alcohol, depression symptom, and QoL information. Tumor site and tumor stage, clinical, and treatment data were abstracted from the patient medical records. MAIN OUTCOME MEASURES: Quality of life was assessed using the Medical Outcomes Study Short-Form 36-Item Health Survey (SF-36) and the Head and Neck QoL (HNQoL) instrument. RESULTS: Of the 570 eligible respondents, the presence of a feeding tube had the most negative impact on QoL, with significant decrements in 6 of the 8 SF-36 scales and all 4 HNQoL scales (P<.01). In descending order of severity, medical comorbid conditions, presence of a tracheotomy tube, chemotherapy, and neck dissection were also associated with significant (P<.05) decrements in QoL domains. Patients who took the survey more than 1 year after diagnosis had improved QoL in 7 of 12 domains. Hospital site, age, education level, sex, race, and marital status were also significant predictors of QoL. CONCLUSION: There are at least 13 demographic and clinical characteristics that are significant predictors of QoL in patients with head and neck cancer, which should be considered when treating patients and conducting QoL studies in the future.

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Metadata

Authors
Terrell, J. E., Ronis, D. L., Fowler, K. E., Bradford, C. R., Chepeha, D. B., Prince, M. E., Teknos, T. N., Wolf, G. T., & Duffy, S. A.
Venue
Archives of Otolaryngology–Head & Neck Surgery
Published
2004-04-01
Volume
130
Issue
4
Pages
401
ISSN
0886-4470 (ISSN-L)
OpenAlex
W2093978092
Cited by
455
References
36
FWCI
19.35
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Clinical Predictors of Quality of Life in Patients With Head and Neck Cancer. https://app.cochat.ai/papers/10.1001/archotol.130.4.401
The paper
Terrell, J. E., Ronis, D. L., Fowler, K. E., Bradford, C. R., Chepeha, D. B., Prince, M. E., Teknos, T. N., Wolf, G. T., & Duffy, S. A. (2004). Clinical Predictors of Quality of Life in Patients With Head and Neck Cancer. Archives of Otolaryngology–Head & Neck Surgery. https://doi.org/10.1001/archotol.130.4.401

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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