The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Clinical Predictors of Quality of Life in Patients With Head and Neck Cancer
Abstract
OBJECTIVE: To identify clinical predictors of quality of life (QoL) in a head and neck cancer patient population. DESIGN, PATIENTS, AND SETTING: A convenience sample of 570 patients with upper aerodigestive tract cancers were surveyed at a tertiary care oncology clinic and Veterans Affairs otolaryngology clinic. INTERVENTIONS: A self-administered health survey was constructed to collect demographic, health, smoking, alcohol, depression symptom, and QoL information. Tumor site and tumor stage, clinical, and treatment data were abstracted from the patient medical records. MAIN OUTCOME MEASURES: Quality of life was assessed using the Medical Outcomes Study Short-Form 36-Item Health Survey (SF-36) and the Head and Neck QoL (HNQoL) instrument. RESULTS: Of the 570 eligible respondents, the presence of a feeding tube had the most negative impact on QoL, with significant decrements in 6 of the 8 SF-36 scales and all 4 HNQoL scales (P<.01). In descending order of severity, medical comorbid conditions, presence of a tracheotomy tube, chemotherapy, and neck dissection were also associated with significant (P<.05) decrements in QoL domains. Patients who took the survey more than 1 year after diagnosis had improved QoL in 7 of 12 domains. Hospital site, age, education level, sex, race, and marital status were also significant predictors of QoL. CONCLUSION: There are at least 13 demographic and clinical characteristics that are significant predictors of QoL in patients with head and neck cancer, which should be considered when treating patients and conducting QoL studies in the future.
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Long‐Term Quality of Life of Patients With Head and Neck Cancer
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Cited by
Prevention and Treatment of Dysphagia and Aspiration After Chemoradiation for Head and Neck Cancer
Rosenthal, D. I., Lewin, J. S., & Eisbruch, A. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2006.06.0079 · Cited by 401
Quality of life research in head and neck cancer: A review of the current state of the science
Murphy, B. A., Ridner, S., Wells, N., & Dietrich, M. (2007) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2006.07.005 · Cited by 317
Quality of Life Scores Predict Survival Among Patients With Head and Neck Cancer
Karvonen-Gutierrez, C. A., Ronis, D. L., Fowler, K. E., Terrell, J. E., Gruber, S. B., & Duffy, S. A. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.12.9510 · Cited by 179
Self-citationBadr, H., Lipnick, D., Diefenbach, M. A., Posner, M., Kotz, T., Miles, B., & Genden, E. (2016) · European Journal of Cancer Care · doi:10.1111/ecc.12396 · Cited by 55
Salient body image concerns of patients with cancer undergoing head and neck reconstruction
Teo, I., Fronczyk, K. M., Guindani, M., Vannucci, M., Ulfers, S. S., Hanasono, M. M., & Fingeret, M. C. (2016) · Head & Neck · doi:10.1002/hed.24415 · Cited by 34
Metadata
- Authors
- Terrell, J. E., Ronis, D. L., Fowler, K. E., Bradford, C. R., Chepeha, D. B., Prince, M. E., Teknos, T. N., Wolf, G. T., & Duffy, S. A.
- Venue
- Archives of Otolaryngology–Head & Neck Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 2004-04-01
- Volume
- 130
- Issue
- 4
- Pages
- 401
- ISSN
- 0886-4470 (ISSN-L)
- OpenAlex
- W2093978092
- Cited by
- 455
- References
- 36
- FWCI
- 19.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- Terrell, J. E., Ronis, D. L., Fowler, K. E., Bradford, C. R., Chepeha, D. B., Prince, M. E., Teknos, T. N., Wolf, G. T., & Duffy, S. A. (2004). Clinical Predictors of Quality of Life in Patients With Head and Neck Cancer. Archives of Otolaryngology–Head & Neck Surgery. https://doi.org/10.1001/archotol.130.4.401
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