The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Expanding the Differential Diagnosis of Chronic Dizziness
Abstract
OBJECTIVE: To improve treatment outcomes for patients with chronic dizziness by identifying clinical conditions associated with persistent symptoms and delineating key diagnostic features that differentiate its causes and direct attention to specific treatments. DESIGN: Prospective cohort study from 1998 to 2004. SETTING: Tertiary care balance center. PATIENTS: A total of 345 men and women, aged 15 to 89 years, referred for evaluation of chronic dizziness (duration of > or =3 months) of uncertain cause. INTERVENTIONS: Patients were systematically directed through multiple specialty examinations until definitive diagnoses were made. MAIN OUTCOME MEASURE: Final diagnoses associated with dizziness. RESULTS: Nearly all patients with chronic subjective dizziness were diagnosed with psychiatric or neurologic illnesses. These included primary and secondary anxiety disorders (n = 206 [59.7%]) and central nervous system conditions (n = 133 [38.6%]), specifically migraine headaches, mild traumatic brain injuries, and neurally mediated dysautonomias. A small number of patients (6 [1.7%]) had dysrhythmias. Four of 5 patients with migraine or dysrhythmias had comorbid anxiety. CONCLUSIONS: Chronic dizziness has several common causes, including anxiety disorders, migraine, traumatic brain injuries, and dysautonomia, that require different treatments. Key features of the clinical history distinguish these illnesses from one another and from active neurotologic conditions. The high prevalence of secondary anxiety may give a false impression of psychogenicity.
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Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The majority of conditions that precede PPPD are acute or episodic in nature.”
In the citing paper
“The most common precipitating conditions are peripheral or central vestibular disorders (25–30% of cases), attacks of vestibular migraine (15–20%), panic attacks or anxiety that manifest prominent dizziness (15% each), concussive injuries of the brain or whiplash injuries of the neck (10–15%), and autonomic disorders (7%).”
In the citing paper
“Positive results indicate that an anxiety or depressive disorder is likely, either as the sole cause of vestibular symptoms or co-existing with PPPD [12, 58, 75, 79].”
In the citing paper
“The average duration of illness at the time of tertiary consultation was 4.5 years with some patients experiencing symptoms for decades [13, 79].”
In the citing paper
“No epidemiologic studies are available for PPPD, but its prevalence and incidence may be estimated from research done on patients with PPV, VV, CSD, and chronic dizziness following acute vestibular syndromes [7, 12, 23, 28, 30, 79].”
In the citing paper
“The average age of patients presenting for evaluation of PPV, CSD, and PPPD is the mid-40 s, with a range from adolescence to late adulthood [10, 79, 100].”
In the citing paper
“Clinical epidemiologic data from tertiary care centers with special interest in PPV [13] and CSD [79] showed their prevalence to be 15–20% among all patients presenting for evaluation of vestibular symptoms, making them the most common diagnoses among young adults and the second most common among all adults, trailing only BPPV.”
In the citing paper
“CSD was a step in that direction based in part on the physical features of PPV [79].”
Citations
Cites
Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052
Guidelines on Management (diagnosis and treatment) of syncope ? update 2004
Brignole, M., Alboni, P., Benditt, D. G., Bergfeldt, L., Blanc, J., Thomsen, P. E. B., van Dijk, J. G., Fitzpatrick, A. P., Hohnloser, S. H., Janousek, J., et al. (2004) · EP Europace · doi:10.1016/j.eupc.2004.08.008 · Cited by 650
Migraine in the United States: Epidemiology and patterns of health care use
Lipton, R. B., Scher, A. I., Kolodner, K., Liberman, J., Steiner, T. J., & Stewart, W. F. (2002) · Neurology · doi:10.1212/wnl.58.6.885 · Cited by 616
Summary of the WHO collaborating centre for neurotrauma task force on mild traumatic brain injury
Holm, L. W., Cassidy, J. D., Carroll, L., & Borg, J. (2005) · Journal of Rehabilitation Medicine · doi:10.1080/16501970510027321 · Cited by 467
Migraine-Related Vestibulopathy
Cass, S. P., Ankerstjerne, J. K. B., Yetışer, S., FURMAN, J. M. R., Balaban, C. D., & Aydoǧan, B. (1997) · Annals of Otology Rhinology & Laryngology · doi:10.1177/000348949710600302 · Cited by 309
Which comes first? Psychogenic dizziness versus otogenic anxiety
Staab, J. P., & Ruckenstein, M. J. (2003) · The Laryngoscope · doi:10.1097/00005537-200310000-00010 · Cited by 265
Self-citationCharacterizing and Treating Dizziness after Mild Head Trauma
Hoffer, M. E., Gottshall, K. R., Moore, R., Balough, B. J., & Wester, D. C. (2004) · Otology & Neurotology · doi:10.1097/00129492-200403000-00009 · Cited by 197
Migraine-anxiety related dizziness (MARD): a new disorder?
Furman, J. M. R. (2004) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.048926 · Cited by 187
Anxiety disorders and other psychiatric subgroups in patients complaining of dizziness
Eckhardt‐Henn, A., Breuer, P., Thomalske, C., Hoffmann, S. O., & Hopf, H. C. (2002) · Journal of Anxiety Disorders · doi:10.1016/s0887-6185(02)00226-8 · Cited by 187
GODEMANN, F., SIEFERT, K., HANTSCHKEBRUGGEMANN, M., NEU, P., SEIDL, R., & STROHLE, A. (2005) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2004.12.006 · Cited by 154
Cited by
Sorted by citations
Staab, J. P., Eckhardt-Henn, A., Horii, A., Jacob, R., Strupp, M., Brandt, T., & Bronstein, A. (2017) · Journal of Vestibular Research · doi:10.3233/ves-170622 · Cited by 840
Self-citationPopkirov, S., Staab, J. P., & Stone, J. (2018) · Practical Neurology · doi:10.1136/practneurol-2017-001809 · Cited by 334
Self-citationNeff, B. A., Staab, J. P., Eggers, S. D., Carlson, M. L., Schmitt, W. R., Van Abel, K. M., Worthington, D. K., Beatty, C. W., Driscoll, C. L., & Shepard, N. T. (2012) · Otology & Neurotology · doi:10.1097/mao.0b013e31825d644a · Cited by 231
“A consensus conference of dizziness sub-specialists reviewed database entries and rendered final study diagnoses based on the AAO-HNS definition of MD (11), second edition of International Classification of Headache Disorders (ICHD-II, IHS) (37) criteria for migraine with and without aura, Neuhauser criteria for defin…”
BackgroundMethodDieterich, M., & Staab, J. P. (2016) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000417 · Cited by 227
Self-citationBalaban, C. D., Jacob, R. G., & FURMAN, J. M. R. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.19 · Cited by 219
Metadata
- Authors
- Staab, J. P., & Ruckenstein, M. J.
- Affiliations
- University of Pennsylvania Health System (US)
- University of Pennsylvania (US)
- ORCID
- Staab, Jeffrey P.
- Venue
- Archives of Otolaryngology–Head & Neck Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 2007-02-01
- Volume
- 133
- Issue
- 2
- Pages
- 170
- ISSN
- 0886-4470 (ISSN-L)
- OpenAlex
- W2099190753
- Cited by
- 217
- References
- 16
- Citations by year
- 2026: 8 · 2025: 17 · 2024: 12 · 2023: 24 · 2022: 11 · 2021: 20 · 2020: 18 · 2019: 10 · 2018: 10 · 2017: 5 · 2016: 13 · 2015: 12 · 2014: 11 · 2013: 9 · 2012: 9
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Otolaryngology - Head and Neck Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
- Keywords
- chronic dizziness, differential diagnosis, anxiety disorders, migraine, mild traumatic brain injury, cardiac arrhythmias, comorbidities, psychogenic dizziness, central nervous system disorders
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Anxiety Disorders, Autonomic Nervous System Diseases, Chronic Disease, Diagnosis, Differential, Diagnostic Techniques, Otological, Dizziness, Female, Humans, Male, Middle Aged, Migraine Disorders, Post-Concussion Syndrome
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