The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Expanding the Differential Diagnosis of Chronic Dizziness
Abstract
OBJECTIVE: To improve treatment outcomes for patients with chronic dizziness by identifying clinical conditions associated with persistent symptoms and delineating key diagnostic features that differentiate its causes and direct attention to specific treatments. DESIGN: Prospective cohort study from 1998 to 2004. SETTING: Tertiary care balance center. PATIENTS: A total of 345 men and women, aged 15 to 89 years, referred for evaluation of chronic dizziness (duration of > or =3 months) of uncertain cause. INTERVENTIONS: Patients were systematically directed through multiple specialty examinations until definitive diagnoses were made. MAIN OUTCOME MEASURE: Final diagnoses associated with dizziness. RESULTS: Nearly all patients with chronic subjective dizziness were diagnosed with psychiatric or neurologic illnesses. These included primary and secondary anxiety disorders (n = 206 [59.7%]) and central nervous system conditions (n = 133 [38.6%]), specifically migraine headaches, mild traumatic brain injuries, and neurally mediated dysautonomias. A small number of patients (6 [1.7%]) had dysrhythmias. Four of 5 patients with migraine or dysrhythmias had comorbid anxiety. CONCLUSIONS: Chronic dizziness has several common causes, including anxiety disorders, migraine, traumatic brain injuries, and dysautonomia, that require different treatments. Key features of the clinical history distinguish these illnesses from one another and from active neurotologic conditions. The high prevalence of secondary anxiety may give a false impression of psychogenicity.
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In the citing paper
“The majority of conditions that precede PPPD are acute or episodic in nature.”
In the citing paper
“The most common precipitating conditions are peripheral or central vestibular disorders (25–30% of cases), attacks of vestibular migraine (15–20%), panic attacks or anxiety that manifest prominent dizziness (15% each), concussive injuries of the brain or whiplash injuries of the neck (10–15%), and autonomic disorders (7%).”
In the citing paper
“Positive results indicate that an anxiety or depressive disorder is likely, either as the sole cause of vestibular symptoms or co-existing with PPPD [12, 58, 75, 79].”
In the citing paper
“The average duration of illness at the time of tertiary consultation was 4.5 years with some patients experiencing symptoms for decades [13, 79].”
In the citing paper
“No epidemiologic studies are available for PPPD, but its prevalence and incidence may be estimated from research done on patients with PPV, VV, CSD, and chronic dizziness following acute vestibular syndromes [7, 12, 23, 28, 30, 79].”
In the citing paper
“The average age of patients presenting for evaluation of PPV, CSD, and PPPD is the mid-40 s, with a range from adolescence to late adulthood [10, 79, 100].”
In the citing paper
“Clinical epidemiologic data from tertiary care centers with special interest in PPV [13] and CSD [79] showed their prevalence to be 15–20% among all patients presenting for evaluation of vestibular symptoms, making them the most common diagnoses among young adults and the second most common among all adults, trailing only BPPV.”
In the citing paper
“CSD was a step in that direction based in part on the physical features of PPV [79].”
Citations
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Self-citationCharacterizing and Treating Dizziness after Mild Head Trauma
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Cited by
Sorted by citations
Staab, J. P., Eckhardt-Henn, A., Horii, A., Jacob, R., Strupp, M., Brandt, T., & Bronstein, A. (2017) · Journal of Vestibular Research · doi:10.3233/ves-170622 · Cited by 840
Self-citationPopkirov, S., Staab, J. P., & Stone, J. (2018) · Practical Neurology · doi:10.1136/practneurol-2017-001809 · Cited by 334
Self-citationNeff, B. A., Staab, J. P., Eggers, S. D., Carlson, M. L., Schmitt, W. R., Van Abel, K. M., Worthington, D. K., Beatty, C. W., Driscoll, C. L., & Shepard, N. T. (2012) · Otology & Neurotology · doi:10.1097/mao.0b013e31825d644a · Cited by 231
“A consensus conference of dizziness sub-specialists reviewed database entries and rendered final study diagnoses based on the AAO-HNS definition of MD (11), second edition of International Classification of Headache Disorders (ICHD-II, IHS) (37) criteria for migraine with and without aura, Neuhauser criteria for defin…”
BackgroundMethodDieterich, M., & Staab, J. P. (2016) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000417 · Cited by 227
Self-citationBalaban, C. D., Jacob, R. G., & FURMAN, J. M. R. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.19 · Cited by 219
Staab, J. P. (2012) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/01.con.0000421622.56525.58 · Cited by 204
Self-citationVisual Dependency and Dizziness after Vestibular Neuritis
Cousins, S., Cutfield, N. J., Kaski, D. N., Palla, A., Seemungal, B. M., Golding, J. F., Staab, J. P., & Bronstein, A. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105426 · Cited by 200
“Indeed, these psychological factors are the foundations of the clinical syndromes of phobic postural vertigo [35] and chronic subjective dizziness [36] that have been used to describe patients with persistent dizziness following acute vestibular events.”
BackgroundSelf-citationDizziness: a diagnostic approach.
Post, R. E., & Dickerson, L. M. (2010) · PubMed · Cited by 169
Vestibular migraine: An update on current understanding and future directions
Huang, T.-C., Wang, S., & Kheradmand, A. (2019) · Cephalalgia · doi:10.1177/0333102419869317 · Cited by 168
“Both VM and PPPD patients may have comorbid psychiatric conditions such as anxiety and depression (44,75–78).”
ResultInfluentialPersistent Postural-Perceptual Dizziness
Staab, J. P. (2020) · Springer eBooks · doi:10.1007/978-3-032-18264-7_62 · Cited by 162
Self-citationIndovina, I., Riccelli, R., Chiarella, G., Petrolo, C., Augimeri, A., Giofrè, L., Lacquaniti, F., Staab, J. P., & Passamonti, L. (2015) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2015.00334 · Cited by 140
“CSDmay be precipitated by neuro-otological, psychiatric, and other medical conditions that cause acute attacks of vertigo, unsteadiness, or dizziness (Staab and Ruckenstein, 2007).”
BackgroundSelf-citationEtiologic distribution of dizziness and vertigo in a referral-based dizziness clinic in South Korea
Kim, H., Lee, J.-O., Choi, J., & Kim, J. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09831-2 · Cited by 144
“These findings are also in line with the findings reported for each disorder; BPPV [27], psychogenic/PPPD [29], vestibular migraine [30] and Meniere’s disease [31], and VN [32].”
ResultLee, J., Lee, E., Kim, J., Lee, Y., Jeong, Y., Choi, B. S., Kim, J., & Staab, J. P. (2018) · Human Brain Mapping · doi:10.1002/hbm.24080 · Cited by 143
“This is consistent with the fMRI results of a previous study (Indovina et al., 2015) that found widespread decreases in connectivity among many of these same areas in patients with CSD in response to sound evoked vestibular stimuli.”
BackgroundInfluentialSelf-citationAnxious, introverted personality traits in patients with chronic subjective dizziness
Staab, J. P., Rohe, D. E., Eggers, S. D. Z., & Shepard, N. T. (2014) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2013.11.008 · Cited by 133
Balaban, C. D., FURMAN, J. M. R., & Staab, J. P. (2013) · Seminars in Neurology · doi:10.1055/s-0033-1356462 · Cited by 138
Self-citationCognitive behavior therapy for chronic subjective dizziness: a randomized, controlled trial
Edelman, S., Mahoney, A., & Cremer, P. D. (2011) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2011.10.009 · Cited by 130
“It is widely acknowledged that a significant proportion of patients seen in neurootologic clinics have dizziness that is maintained by psychologic factors, most notably anxiety [5,9,10].”
BackgroundDizziness: Anxiety, health care utilization and health behavior—
Wiltink, J., Tschan, R., Michal, M., Subič-Wrana, C., Eckhardt‐Henn, A., Dieterich, M., & Beutel, M. E. (2008) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2008.09.012 · Cited by 129
“A recent prospective cohort study underscores the importance of anxiety as a common cause for dizziness along with migraine, traumatic brain injuries, and dysautonomia, requiring a different treatment approach [33].”
BackgroundFunctional (psychogenic) dizziness
(2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-801772-2.00037-0 · Cited by 119
“That is because experimental data show that they occur independently (Brandt, 1996; Staab and Ruckenstein, 2003, 2007a; Eckhardt-Henn, et al., 2008).”
BackgroundInfluentialSelf-citationClinical characteristics of patients with persistent postural-perceptual dizziness
Bittar, R. S. M., & Lins, E. M. D. V. S. (2014) · Brazilian Journal of Otorhinolaryngology · doi:10.1016/j.bjorl.2014.08.012 · Cited by 117
Ruckenstein, M. J., & Staab, J. P. (2009) · Otolaryngologic Clinics of North America · doi:10.1016/j.otc.2008.09.011 · Cited by 118
“Patients with dysautonomias represent a small but significant subgroup of the CSD population.(6,11,12) These patients who have alterations in central neurovascular control can manifest symptoms typical of CSD.”
InfluentialSelf-citationRiccelli, R., Passamonti, L., Toschi, N., Nigro, S. L., Chiarella, G., Petrolo, C., Lacquaniti, F., Staab, J. P., & Indovina, I. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00529 · Cited by 109
“This was because otologic illnesses are known to be the most common triggers of PPPD (10, 36), as was the case in our patient group.”
BackgroundSelf-citationPosttraumatic Vertigo and Dizziness
Giza, C. C., & Fife, T. D. (2013) · Seminars in Neurology · doi:10.1055/s-0033-1354599 · Cited by 94
Inadequate interaction between open- and closed-loop postural control in phobic postural vertigo
Wuehr, M., Pradhan, C., Novozhilov, S., KRAFCZYK, S., Brandt, T. H., Jahn, K., & Schniepp, R. (2012) · Journal of Neurology · doi:10.1007/s00415-012-6797-7 · Cited by 90
“PPV is one of the primary and secondary somatoform dizziness syndromes [2–4] and is also termed visual vertigo syndrome [5] or chronic subjective dizziness [6].”
BackgroundMigraine, vertigo and migrainous vertigo: Links between vestibular and pain mechanisms
Balaban, C. D. (2011) · Journal of Vestibular Research · doi:10.3233/ves-2011-0428 · Cited by 91
“Balance disorders (both neurotologic disease and chronic subjective dizziness) are often co-morbid with psychiatric disorders [24,34,63–65] and with migraine [23,26,45].”
Principles of vestibular physical therapy rehabilitation
Whitney, S. L., & Sparto, P. J. (2011) · Neurorehabilitation · doi:10.3233/nre-2011-0690 · Cited by 85
“With signi fi cant “space and motion” sensitivity [64], “visual vertigo” [11], or chronic subjective dizziness [103,111, 112] patients may become very symptomatic in visually complex environments and cannot function.”
Schniepp, R., Wuehr, M., Huth, S., Pradhan, C., Brandt, T., & Jahn, K. (2014) · Journal of Neurology · doi:10.1007/s00415-014-7259-1 · Cited by 81
“It can be classified among the primary and secondary somatoform dizziness syndromes, which are also termed visual vertigo syndrome [9] or chronic subjective dizziness [40].”
BackgroundThompson, K. J., Goetting, J. C., Staab, J. P., & Shepard, N. T. (2015) · PubMed · doi:10.3233/ves-150551 · Cited by 81
“PPPD, itself, does not produce abnormalities in basic vestibular or oculomotor reflexes such as the vestibulo-ocular reflex or smooth pursuit, but individuals with PPPD may show peripheral or central vestibular deficits related to their triggering or co-existing conditions [16,17].”
Self-citationHabs, M., Strobl, R., Grill, E., Dieterich, M., & Becker‐Bense, S. (2020) · Journal of Neurology · doi:10.1007/s00415-020-10150-9 · Cited by 79
Lins, E. M. D. V. S., Bittar, R. S. M., & Staab, J. P. (2016) · Journal of Vestibular Research · doi:10.3233/ves-160583 · Cited by 78
Self-citationYu, Y., Xue, H., Zhang, Y., & Zhou, J. (2018) · BioMed Research International · doi:10.1155/2018/8518631 · Cited by 74
“And there was a close relationship between PPPD and psychiatric or neurologic illnesses [4].”
BackgroundPersistent postural perceptual dizziness is on a spectrum in the general population
Powell, G., Derry-Sumner, H., Rajenderkumar, D., Rushton, S. K., & Sumner, P. (2020) · Neurology · doi:10.1212/wnl.0000000000009373 · Cited by 78
Yan, Z., Cui, L., Yu, T., Liang, H., Wang, Y., & Chen, C.-F. (2016) · International Journal of Audiology · doi:10.1080/14992027.2016.1211763 · Cited by 70
“…these names do not fully describe the pathogenesis and clinical features, and more recently Staab and Ruckenstein conducted a series of studies and proposed a new concept named chronic subjective dizziness (CSD) (Staab, 2006; Staab, 2006; Staab & Ruckenstein, 2007; Ruckenstein & Staab, 2009).”
BackgroundIndovina, I., Riccelli, R., Staab, J. P., Lacquaniti, F., & Passamonti, L. (2014) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2014.09.005 · Cited by 68
“Thesemodelsmay extend to other conditionswith vestibularanxiety interactions, such as height phobia and phobic postural vertigo [42,43] or chronic subjective dizziness (CSD) [2,44,45].”
BackgroundSelf-citationEkwall, A. K., Lindberg, Å., & Magnusson, M. (2009) · Gerontology · doi:10.1159/000235812 · Cited by 67
“Other factors, such as increased need for medications in higher age, and those medications given may also be important.Previous research has aimed at describing differences between dizzy and not dizzy elderly. Here, a regression analysis, only including persons with dizziness, was undertaken to define the factors affe…”
BackgroundPassamonti, L., Riccelli, R., Lacquaniti, F., Staab, J. P., & Indovina, I. (2019) · Journal of Vestibular Research · doi:10.3233/ves-190653 · Cited by 65
Self-citationPersistent vertigo and dizziness after mild traumatic brain injury
Fife, T. D., & Kalra, D. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12678 · Cited by 62
Persistent Postural-Perceptual Dizziness
Staab, J. P. (2023) · Neurologic Clinics · doi:10.1016/j.ncl.2023.04.003 · Cited by 70
Self-citationNigro, S. L., Indovina, I., Riccelli, R., Chiarella, G., Petrolo, C., Lacquaniti, F., Staab, J. P., & Passamonti, L. (2018) · Brain Imaging and Behavior · doi:10.1007/s11682-018-9900-6 · Cited by 62
“This was because otologic illnesses are known to be the most common triggers of PPPD (Staab and Ruckenstein 2003, 2007), as was the case in our patient group.”
BackgroundSelf-citationMal de debarquement syndrome: new insights
Cha, Y. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12701 · Cited by 61
Persistent Postural-Perceptual Dizziness: A Matter of Higher, Central Dysfunction?
Holle, D., Steinberg, B. S., Wurthmann, S., Naegel, S., Ayzenberg, I., Diener, H., Katsarava, Z., & Obermann, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0142468 · Cited by 59
“[6] In 2014 new consensus criteria were established and the clinical condition was renamed PPPD.”
BackgroundPersistent Postural-Perceptual Dizziness (PPPD) from Brain Imaging to Behaviour and Perception
Castro, P., Bancroft, M. J., Arshad, Q., & Kaski, D. N. (2022) · Brain Sciences · doi:10.3390/brainsci12060753 · Cited by 64
“On the other hand, patients with PPPD exhibit heightened awareness or attention to moving or complex visual stimuli [10,19–22], but also increased sensitivity to self and object motion [23].”
BackgroundEggers, S. D. Z., Staab, J. P., Neff, B. A., Goulson, A. M., Carlson, M. L., & Shepard, N. T. (2011) · Otology & Neurotology · doi:10.1097/mao.0b013e31822a1c67 · Cited by 55
“The small number (n = 18) of subjects with nonmigraine headaches related to vestibular symptoms included patients with traumatic brain injury producing both nonmigrainous headaches and vestibular symptoms and individuals with comorbid chronic daily dizziness and headache (e.g., CSD plus chronic tensiontype headache) t…”
BackgroundInfluentialSelf-citationDoble, J. E., Feinberg, D. L., Rosner, M., & Rosner, A. J. (2010) · PM&R · doi:10.1016/j.pmrj.2010.01.011 · Cited by 52
“balance and gait, motion sickness), vision (blurred vision, reading difficulties, diplopia, light sensitivity), and psychiatric symptoms (anxiety, panic, agoraphobia) (Table 1) [2-11].”
BackgroundComprehensive Clinical Profile of Mal De Debarquement Syndrome
Cha, Y., Cui, Y. Y., & Baloh, R. W. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00261 · Cited by 52
“The PPPD diagnosis was created to encompass the characteristics of chronic subjective dizziness, space, and motion discomfort, and visual vertigo (48, 49).”
White Paper: Movement System Diagnoses in Neurologic Physical Therapy
Hedman, L. D., Quinn, L., Gill-Body, K. M., Brown, D. A., Quiben, M., Riley, N., & Scheets, P. L. (2018) · Neurology Report · doi:10.1097/npt.0000000000000215 · Cited by 50
Piker, E. G., Jacobson, G. P., McCaslin, D. L., & Grantham, S. L. (2008) · Journal of the American Academy of Audiology · doi:10.3766/jaaa.19.4.6 · Cited by 49
“A similar finding has been reported by Yardley and colleagues (2001), who investigated dizziness in a large community sample and found that women were more likely to report dizziness than men.”
BackgroundResultChronic subjective dizziness: Analysis of underlying personality factors
Chiarella, G., Petrolo, C., Riccelli, R., Giofrè, L., Olivadese, G., Gioacchini, F. M., Scarpa, A., Cassandro, E., & Passamonti, L. (2016) · Journal of Vestibular Research · doi:10.3233/ves-160590 · Cited by 48
“Overall, our approach was analogous to that described in Staab et al. [23] who found that CSD patients tend to have higher neuroticism and lower extraversion and openness scores when compared to patients with other vestibular disorders that cause similar levels of disability.”
InfluentialVestibular symptoms and history taking
Bisdorff, A. R. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-444-63437-5.00006-6 · Cited by 48
Teh, C. S.-L., & Prepageran, N. (2021) · Journal of Vestibular Research · doi:10.3233/ves-210087 · Cited by 47
“As physical examination, clinical laboratory testing and vestibular evaluation may be normal in PPPD [21, 22], advances in neuroimaging have provided new insights in patients with PPPD illustrating the delicate changes in functional activity and inter-network connectivity involving the vestibular,…”
Cha, Y., Deblieck, C., & Wu, A. D. (2016) · Otology & Neurotology · doi:10.1097/mao.0000000000001045 · Cited by 46
Eren, O. E., Filippopulos, F. M., Sönmez, K., Möhwald, K., Straube, A. M., & Schöberl, F. (2018) · Journal of Neurology · doi:10.1007/s00415-018-8894-8 · Cited by 47
“In a substantial portion of patients with PPPD, a comorbidity with anxiety disorders and depression is found [4, 5].”
BackgroundComorbidities in vestibular migraine
Eggers, S. D. Z., Neff, B. A., Shepard, N. T., & Staab, J. P. (2014) · Journal of Vestibular Research · doi:10.3233/ves-140525 · Cited by 47
“…clinical syndrome of chronic subjective dizziness (CSD) defined by 3 months or more of persistent, non-vertiginous dizziness exacerbated by self or environmental motion, complex visual environments, and precision visual tasks that included migraine and anxiety in its differential diagnosis [55,66].”
Self-citationRocking dizziness and headache: A two-way street
Cha, Y., & Cui, Y. (2013) · Cephalalgia · doi:10.1177/0333102413487999 · Cited by 44
“A hallmark difference between MdDS and CSD is that symptoms of CSD are worsened by exposure to motion, whereas the rocking of MdDS improves with motion (7).”
BackgroundNonlinear Variability of Body Sway in Patients with Phobic Postural Vertigo
Schniepp, R., Wuehr, M., Pradhan, C., Novozhilov, S., KRAFCZYK, S., Brandt, T., & Jahn, K. (2013) · Frontiers in Neurology · doi:10.3389/fneur.2013.00115 · Cited by 43
“PPV is one of the primary and secondary somatoform dizziness syndromes (2–4) and is also termed visual vertigo syndrome (5) or chronic subjective dizziness (6).”
BackgroundA Cognitive-Behavioral Model of Persistent Postural-Perceptual Dizziness
Whalley, M. G., & Cane, D. A. (2017) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2016.03.003 · Cited by 40
Guo, J., Wang, J., Liang, P., Tian, E., Liu, D., Guo, Z., Chen, J., Zhang, Y., Zhou, Z., Kong, W., et al. (2024) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2024.5360 · Cited by 43
“According to an epidemiologic study, PPPD accounts for 15‑20% of the cases encountered at the clinical centers for vertigo (104).”
BackgroundMultifactorial Characteristics of Pediatric Dizziness and Imbalance
Wang, A., Zhou, G., Lipson, S. E., Kawai, K., Corcoran, M., & Brodsky, J. R. (2020) · The Laryngoscope · doi:10.1002/lary.29024 · Cited by 40
Persistent Postural-Perceptual Dizziness in Children and Adolescents
Wang, A., Fleischman, K. M., Kawai, K., Corcoran, M., & Brodsky, J. R. (2021) · Otology & Neurotology · doi:10.1097/mao.0000000000003212 · Cited by 40
Subtypes of Persistent Postural-Perceptual Dizziness
Yagi, C., Morita, Y., Kitazawa, M., Yamagishi, T., Ohshima, S., Izumi, S., Takahashi, K., & Horii, A. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.652366 · Cited by 38
Central vestibular dysfunction: don’t forget vestibular rehabilitation
Zhang, S., Liu, D., Tian, E., Wang, J., Guo, Z., & Kong, W. (2022) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2022.2106129 · Cited by 39
“have peripheral or central vestibular deficits related to the triggering or co-existing conditions [118].”
BackgroundFunctional and psychiatric vestibular disorders
Staab, J. P. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-444-63437-5.00024-8 · Cited by 37
“Incidence and prevalence estimates derived from research on phobic postural vertigo (Brandt and Dieterich, 1986), chronic subjective dizziness (Staab and Ruckenstein, 2007), and long-term outcomes of acute vestibular syndromes suggest that it is the second most common diagnosis (after benign…”
BackgroundInfluentialSelf-citationVestel, C. D., Hertogh, W. D., Rompaey, V. V., & Vereeck, L. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.880714 · Cited by 36
“Their inclusion criteria were (1) speaking the Dutch language; and (2) being at least 18 years old.”
BackgroundInfluentialInfluence of sex hormones on vestibular disorders
Mucci, V., Hamid, M. A., Jacquemyn, Y., & Browne, C. J. (2021) · Current Opinion in Neurology · doi:10.1097/wco.0000000000001019 · Cited by 35
“Hormonal changes have been attributed to the higher prevalence of females with PPPD, with a female:male ratio of 2:1 [34,41], however, there have been no investigations evaluating the hormonal profiles of these subjects, though hormonal research has become a point of interest in VM and MdDS.”
BackgroundInfluentialAnxiety among individuals with visual vertigo and vestibulopathy
Zur, O., Schoen, G., Dickstein, R., Feldman, J., Berner, Y., Dannenbaum, E., & Fung, J. (2015) · Disability and Rehabilitation · doi:10.3109/09638288.2014.1002577 · Cited by 37
“Almost half of older adults with dizziness or vertigo are diagnosed with vestibulopathy [1] and 60% of those with vestibulopathy have symptoms of anxiety [2].”
BackgroundMigraine Features in Patients with Persistent Postural-Perceptual Dizziness
Sarna, B., Risbud, A., Lee, A., Muhonen, E. G., Abouzari, M., & Djalilian, H. R. (2021) · Annals of Otology Rhinology & Laryngology · doi:10.1177/00034894211007233 · Cited by 35
Naguib, M. B., Madian, Y. T., Refaat, M., Mohsen, O. A. A. H., Tabbakh, M. T. E., & Abo-Setta, A. (2011) · The Journal of Laryngology & Otology · doi:10.1017/s002221511100291x · Cited by 33
Visually-induced dizziness is associated with sensitivity and avoidance across all senses
Powell, G., Derry-Sumner, H., Shelton, K., Rushton, S., Hedge, C., Rajenderkumar, D., & Sumner, P. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09817-0 · Cited by 31
Autonomic nervous system function in chronic dizziness
Staab, J. P., & Ruckenstein, M. J. (2007) · Otology & Neurotology · doi:10.1097/mao.0b013e31805c74a7 · Cited by 31
“In this tertiary care population, primary autonomic dysfunction was four times more prevalent than cardiac dysrhythmias and half as common as traumatic brain injuries or migraine headaches as a cause of dizziness (13).”
BackgroundSelf-citationPersistent postural-perceptual dizziness: A functional neuro-otologic disorder
Yagi, C., Kimura, A., & Horii, A. (2024) · Auris Nasus Larynx · doi:10.1016/j.anl.2023.12.008 · Cited by 32
Voxel Based Morphometry Alterations in Mal de Debarquement Syndrome
Cha, Y., & Chakrapani, S. (2015) · PLoS ONE · doi:10.1371/journal.pone.0135021 · Cited by 30
“This may help explain why chronic rocking dizziness specifically is often associated with anxiety and affective disorders [4,5].”
BackgroundNa, S., Im, J. J., Jeong, H. S., Lee, E., Lee, T.-K., Chung, Y., & Song, I. (2018) · Journal of Neural Transmission · doi:10.1007/s00702-018-1948-3 · Cited by 31
Kutz, J. W. (2010) · Medical Clinics of North America · doi:10.1016/j.mcna.2010.05.011 · Cited by 28
Cao, Z., Liu, X., Ju, Y., & Zhao, X. (2021) · Journal of Neurology · doi:10.1007/s00415-021-10558-x · Cited by 27
“Compared with HCs, CSD patients showed decreased activations in the PIVC including the posterior and anterior insula, inferior frontal gyrus (IFg), hippocampus, and anterior cingulate cortex (ACC).”
MethodInfluentialLong-term symptoms in dizzy patients examined in a university clinic
Wilhelmsen, K. T., Ljunggren, A. E., Goplen, F. K., Eide, G. E., & Nordahl, S. H. G. (2009) · BMC Ear Nose and Throat Disorders · doi:10.1186/1472-6815-9-2 · Cited by 27
“This has been suggested in patients with vestibular neuritis [21,39] and benign paroxysmal positional vertigo [39].”
InfluentialWhat’s in a Name? Chronic Vestibular Migraine or Persistent Postural Perceptual Dizziness?
Tarnutzer, A. A., & Kaski, D. N. (2023) · Brain Sciences · doi:10.3390/brainsci13121692 · Cited by 25
“In other studies, 26% [30] and 17% [31] of PPPD patients also met diagnostic criteria for migraine headaches, where VM seemed to act as a trigger and/or perpetuating factor for PPPD [25,28].”
Mempouo, E., Lau, K., Green, F., Bowes, C., & Ray, J. (2021) · The Journal of Laryngology & Otology · doi:10.1017/s0022215121002127 · Cited by 26
McCaslin, D. L., Shepard, N. T., Hollman, J. H., & Staab, J. P. (2021) · Otology & Neurotology · doi:10.1097/mao.0000000000003393 · Cited by 28
Self-citationMedically unexplained symptoms and somatisation in ENT
Ullas, G., McClelland, L., & Jones, N. S. (2013) · The Journal of Laryngology & Otology · doi:10.1017/s0022215113000339 · Cited by 25
Persistence of Symptoms in Primary Somatoform Vertigo and Dizziness
Tschan, R., Best, C., Wiltink, J., Beutel, M. E., Dieterich, M., & Eckhardt‐Henn, A. (2013) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0b013e318288e2ad · Cited by 25
“(J Nerv Ment Dis 2013;201: 328Y333) P rimary somatoform vertigo and dizziness (SVD) as a correlate ofa psychopathological process is a common diagnosis in psychosomatic health care (Kroenke et al., 2000; Staab and Ruckenstein, 2007b).”
BackgroundInfluentialAnxiety, Mood, and Personality Disorders in Patients with Benign Paroxysmal Positional Vertigo
Kozak, H. H., Dündar, M. A., Uca, A. U., Uğuz, F., Turgut, K., Altaş, M., Tekin, G., & Aziz, S. K. (2016) · Nöro Psikiyatri Arşivi · doi:10.5152/npa.2016.18143 · Cited by 25
“Depression is a psychological consequence that occurs following stressful or persistent symptoms such as dizziness (30,31).”
BackgroundRadziej, K., Schmid, G., Dinkel, A., Zwergal, A., & Lahmann, C. (2015) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2015.05.005 · Cited by 24
Presbivertigem como causa de tontura no idoso
Felipe, L., Cunha, L. C. M., da Cunha, F. C. M., Cintra, M. T. G., & Gonçalves, D. U. (2008) · Pró-Fono Revista de Atualização Científica · doi:10.1590/s0104-56872008000200005 · Cited by 24
Morisod, B., Mermod, M., & Maire, R. (2017) · Journal of Vestibular Research · doi:10.3233/ves-170628 · Cited by 23
“Most of these patients relate a history of 47 past neurotologic disorder [26], or have either pre48 existing or quiescent anxiety disorders that have been 49”
Schröder, L., von Werder, D., Ramaioli, C., Wächtler, T., Henningsen, P., Glasauer, S., & Lehnen, N. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.685590 · Cited by 22
Clinical clues to a dizzying headache
Staab, J. P. (2011) · Journal of Vestibular Research · doi:10.3233/ves-2011-0426 · Cited by 23
Self-citationVestibular migraine and persistent postural perceptual dizziness
Eggers, S. D. Z., & Staab, J. P. (2024) · Handbook of clinical neurology · doi:10.1016/b978-0-12-823357-3.00028-8 · Cited by 23
Self-citationClinical classification and neuro-vestibular evaluation in chronic dizziness
Oh, S., Kim, D., Yang, T.-H., Shin, B., & Jeong, S. (2014) · Clinical Neurophysiology · doi:10.1016/j.clinph.2014.03.030 · Cited by 21
“…non-vertiginous dizziness, subjective imbalance, and hypersensitivity to motion cues in the absence of active vestibular or neurologic deficits (Staab and Ruckenstein, 2007). http://dx.doi.org/10.1016/j.clinph.2014.03.030 1388-2457/ 2014 International Federation of Clinical Neurophysiology.”
BackgroundInfluentialIndovina, I., Conti, A., Lacquaniti, F., Staab, J. P., Passamonti, L., & Toschi, N. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00874 · Cited by 20
Self-citationHonaker, J. A., Gilbert, J. M., & Staab, J. P. (2010) · American Journal of Audiology · doi:10.1044/1059-0889(2009/09-0013 · Cited by 20
Self-citationPersistent Postural Perceptual Dizziness in Episodic Vestibular Disorders
Gambacorta, V., D’Orazio, A., Pugliese, V., Giovanni, A. D., Ricci, G., & Faralli, M. (2022) · Audiology Research · doi:10.3390/audiolres12060058 · Cited by 20
Im, J. J., Na, S., Kang, S., Jeong, H. S., Lee, E., Lee, T.-K., Ahn, W., Chung, Y., & Song, I. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.868976 · Cited by 20
“Prior to being established as a new diagnostic term, there were several clinical syndromes of functional dizziness such as chronic subjective dizziness (CSD) (4, 5), phobic postural vertigo (PPV) (6), visual vertigo (VV) (7), and space-motion discomfort (SMD) (8, 9).”
BackgroundPersistent postural-perceptual dizziness: current approaches to diagnosis and treatment
Antonenko, L. M., & Zastenskaya, E. N. (2019) · Neurology neuropsychiatry Psychosomatics · doi:10.14412/2074-2711-2019-4-136-140 · Cited by 19
Fang, Z., Huang, K., Gil, C.-H., Jeong, J.-W., Yoo, H.-R., & Kim, H.-G. (2020) · Scientific Reports · doi:10.1038/s41598-020-58218-w · Cited by 17
Autonomic dysfunction in chronic persistent dizziness
Lee, H., & Kim, H. A. (2014) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2014.06.048 · Cited by 18
“5%) of purely autonomic dizziness described in previous reports [9,10].”
InfluentialPonsford, J. L., Olver, J., Ponsford, M. W., & Schönberger, M. (2010) · Brain Impairment · doi:10.1375/brim.11.3.253 · Cited by 17
Vestibular rehabilitation in patients with persistent postural-perceptual dizziness
Tramontano, M., Princi, A. A., Angelis, S. D., Indovina, I., & Manzari, L. (2021) · Hearing Balance and Communication · doi:10.1080/21695717.2021.1975986 · Cited by 17
“[2,3], visually induced dizziness [4], phobic postural”
Chae, R., Krauter, R., Pasquesi, L. L., & Sharon, J. D. (2022) · Journal of Vestibular Research · doi:10.3233/ves-210117 · Cited by 16
Migraine management for the otolaryngologist
Brooks, K. A., Tawk, K., Djalilian, H. R., & Hobson, C. E. (2023) · Laryngoscope Investigative Otolaryngology · doi:10.1002/lio2.1109 · Cited by 18
Lins, E. M. D. V. S., Bittar, R. S. M., Bazán, P. R., Amaro, E., & Staab, J. P. (2020) · International Archives of Otorhinolaryngology · doi:10.1055/s-0040-1716572 · Cited by 16
Self-citationPowell, G., Penacchio, O., Derry-Sumner, H., Rushton, S. K., Rajenderkumar, D., & Sumner, P. (2021) · Journal of Vestibular Research · doi:10.3233/ves-190578 · Cited by 20
“It often develops following a vestibular insult [1, 6, 51, 63], but it is also associated with other central disorders such as anxiety [5, 31, 53, 62, 64, 65] and migraine [51-53, 63, 66].”
Influential
Metadata
- Authors
- Staab, J. P., & Ruckenstein, M. J.
- Affiliations
- University of Pennsylvania Health System (US)
- University of Pennsylvania (US)
- ORCID
- Staab, Jeffrey P.
- Venue
- Archives of Otolaryngology–Head & Neck Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 2007-02-01
- Volume
- 133
- Issue
- 2
- Pages
- 170
- ISSN
- 0886-4470 (ISSN-L)
- OpenAlex
- W2099190753
- Cited by
- 217
- References
- 16
- Citations by year
- 2026: 8 · 2025: 17 · 2024: 12 · 2023: 24 · 2022: 11 · 2021: 20 · 2020: 18 · 2019: 10 · 2018: 10 · 2017: 5 · 2016: 13 · 2015: 12 · 2014: 11 · 2013: 9 · 2012: 9
- FWCI
- 3.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Otolaryngology - Head and Neck Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
- Keywords
- chronic dizziness, differential diagnosis, anxiety disorders, migraine, mild traumatic brain injury, cardiac arrhythmias, comorbidities, psychogenic dizziness, central nervous system disorders
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Anxiety Disorders, Autonomic Nervous System Diseases, Chronic Disease, Diagnosis, Differential, Diagnostic Techniques, Otological, Dizziness, Female, Humans, Male, Middle Aged, Migraine Disorders, Post-Concussion Syndrome
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