The "Switch Process" in Manic-Depressive Illness: I. A Systematic Study of Sequential Behavioral Changes
Abstract
This paper presents the first of a three-part report on behavioral and biological aspects of the "switch process" in a group of manicdepressive patients. It documents a regular temporal pattern of change in thought and mood observed during ten spontaneous episodes of switches from depression into mania and seven episodes of switches out of mania into depression. Patients were described in detail and their behavior rated every eight hours on a longitudinal basis throughout these periods of change. The depressive period prior to the switch into mania was characterized by moderate depression, seclusiveness, nonverbalization, and dozing. Each of the ten episodes of mania was preceded by a normal or transitional period which was manifested by sudden appearance of spontaneous speech and motor activity and normalization of mood. Total sleep time was markedly reduced on the day prior to the switch into mania and remained low during the manic period.
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In bipolar disorder, episodes of mania and depression are accompanied by dramatic changes in the timing and duration of sleep.
“In bipolar disorder, episodes of mania and depression are accompanied by dramatic changes in the timing and duration of sleep1–4.”
From Bipolar mood cycles associated with lunar entrainment of a circadian rhythm (2018) · cites this paper as [1]
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Self-citationCATECHOLAMINE RECEPTOR STABILIZATION: A POSSIBLE MODE OF LITHIUM'S ANTI-MANIC ACTION
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- Authors
- Bunney, W. E.
- Corresponding author
- Bunney, William E.
- ORCID
- Bunney, William E.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1972-09-01
- Volume
- 27
- Issue
- 3
- Pages
- 295
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2084987373
- Cited by
- 177
- References
- 19
- Citations by year
- 2026: 1 · 2023: 1 · 2021: 2 · 2018: 2 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 1 · 2013: 1 · 2012: 3
- FWCI
- 7.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of General Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- bipolar disorder, mania, depression, mood changes, behavior change, sleep deprivation, spontaneous speech
- MeSH terms
- Affect, Aggression, Arousal, Behavior, Bipolar Disorder, Humans, Motor Activity, Psychiatric Status Rating Scales, Sleep, Social Isolation, Stress, Psychological, Time Factors, Verbal Behavior
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