The DOI matches its Crossref record.
Single-Case Experimental Designs: Uses in Applied Clinical Research
Abstract
The difficulty of developing and evaluating effective treatments in psychiatry and clinical psychology points out the inadequacy of current research methodology involving comparisons of large groups. An alternative approach firmly founded in the scientific method, but particularly appropriate to the study of complex behavior disorders, is the single-case experimental design. In this paper, examples of different single-case designs actually employed in applied clinical research are presented and discussed. Practical problems arising during the course of research are highlighted and some basic procedures outlined. General questions on variability, representativeness of finidings, and clinical versus statistical significance are briefly discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
The n-of-1 clinical trial: the ultimate strategy for individualizing medicine?
Lillie, E. O., Patay, B., Diamant, J., Issell, B., Topol, E. J., & Schork, N. J. (2011) · Personalized Medicine · doi:10.2217/pme.11.7 · Cited by 706
The Good Behavior Game: A Best Practice Candidate as a Universal Behavioral Vaccine
Embry, D. D. (2002) · Clinical Child and Family Psychology Review · doi:10.1023/a:1020977107086 · Cited by 365
Hayes, S. C., Ciarrochi, J., Hofmann, S. G., Chin, F., & Sahdra, B. (2022) · Behaviour Research and Therapy · doi:10.1016/j.brat.2022.104155 · Cited by 234
Singh, N. N., Lancioni, G. E., Winton, A. S. W., Karazsia, B. T., Myers, R. E., Latham, L. L., & Singh, J. (2014) · Mindfulness · doi:10.1007/s12671-014-0321-3 · Cited by 156
Vlaeyen, J. W. S., Morley, S., & Crombez, G. (2016) · Behaviour Research and Therapy · doi:10.1016/j.brat.2016.08.016 · Cited by 117
Metadata
- Authors
- Barlow, D. H.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1973-09-01
- Volume
- 29
- Issue
- 3
- Pages
- 319
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2060573307
- Cited by
- 341
- References
- 0
- FWCI
- 26.55
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Single-Case Experimental Designs: Uses in Applied Clinical Research. https://app.cochat.ai/papers/10.1001/archpsyc.1973.04200030017003
- The paper
- Barlow, D. H. (1973). Single-Case Experimental Designs: Uses in Applied Clinical Research. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1973.04200030017003
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
