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Why Do Schizophrenic Patients Refuse to Take Their Drugs?
Abstract
Patients with schizophrenia often do not take their prescribed phenothiazines. This survey focused on the drug-taking behavior of 85 mostly chronic schizophrenic patients during a two-year period. Thirty-nine (46%) of these patients took less antipsychotic drug than the amount prescribed. The reluctance to take antipsychotic medication was significantly associated with extrapyramidal symptoms—most notably a subtle akathisia. It is proposed that drug reluctance and dysphoric response to antipsychotic drugs are often extrapyramidally based.
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Cited by
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Cramer, J. A., & Rosenheck, R. (1998) · Psychiatric Services · doi:10.1176/ps.49.2.196 · Cited by 725
Adequacy of Treatment for Serious Mental Illness in the United States
Wang, P. S., Demler, O., & Kessler, R. C. (2002) · American Journal of Public Health · doi:10.2105/ajph.92.1.92 · Cited by 581
Carbon, M., Kane, J. M., Leucht, S., & Correll, C. U. (2018) · World Psychiatry · doi:10.1002/wps.20579 · Cited by 214
Movement disorders induced by antipsychotic drugs: implications of the CATIE schizophrenia trial.
Caroff, S. N., Hurford, I., Lybrand, J., & Campbell, E. C. (2011) · Neurologic Clinics · doi:10.1016/j.ncl.2010.10.002 · Cited by 188
Barkhof, E., Meijer, C. J., de Sonneville, L. M. J., Linszen, D. H., & de Haan, L. (2012) · European Psychiatry · doi:10.1016/j.eurpsy.2011.02.005 · Cited by 183
Metadata
- Authors
- Van Putten, T.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1974-07-01
- Volume
- 31
- Issue
- 1
- Pages
- 67
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W1966155579
- Cited by
- 572
- References
- 0
- FWCI
- 5.08
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
