The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Estrogen Therapy for Severe Persistent Depressions in Women
Abstract
Positive results are reported from a double-blind study of estrogen therapy administered to severely depressed, inpatient women who had failed to respond to various conventional treatments of depression. Large doses of oral conjugated estrogen were administered for a three-month period to 23 premenopausal and postmenopausal inpatient women. Placebos were administered for a comparable period to 17 similar patients. The posttreatment Hamilton ratings of depression were significantly reduced in the estrogen-treated group, but not in the placebo group. Possible physiological mechanisms are discussed. The risk-benefit ratio for estrogen therapy of depression in these patients was judged to be favorable. However, periodic endometrial biopsies are required to monitor the endometrial response of women receiving high doses of estrogens.
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Citations
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
The Brief Psychiatric Rating Scale.
Overall, J. E., & Gorham, D. R. (1962) · Psychological Reports · doi:10.2466/pr0.1962.10.3.799 · Cited by 11,090
BALL, P., KNUPPEN, R., HAUPT, M., & BREUER, H. (1972) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-34-4-736 · Cited by 280
Cited by
Estrogen and cognitive functioning in women
Sherwin, B. B. (2003) · Endocrine Reviews · doi:10.1210/er.2001-0016 · Cited by 560
Estrogen control of central neurotransmission: Effect on mood, mental state, and memory
Fink, G., Sumner, B. E. H., Rosie, R., Grace, O., & Quinn, J. P. (1996) · Cellular and Molecular Neurobiology · doi:10.1007/bf02088099 · Cited by 431
Estrogen Replacement Therapy and Cognitive Function in Older Women
Barrett-Connor, E. (1993) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1993.03500200051032 · Cited by 377
Biological and social contributions to negative affect in young adolescent girls
Brooks-Gunn, J., & Warren, M. P. (1989) · Child Development · doi:10.2307/1131069 · Cited by 359
Deecher, D., Andree, T. H., Sloan, D., & Schechter, L. E. (2008) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.10.006 · Cited by 270
Metadata
- Authors
- Klaiber, E. L.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1979-05-01
- Volume
- 36
- Issue
- 5
- Pages
- 550
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W1965532261
- Cited by
- 353
- References
- 3
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Klaiber, E. L. (1979). Estrogen Therapy for Severe Persistent Depressions in Women. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1979.01780050060006
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
