The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Low-Dose Neuroleptic Treatment of Outpatient Schizophrenics: I. Preliminary Results for Relapse Rates
Abstract
In an attempt to begin to establish minimum effective dosage requirements for the maintenance treatment of schizophrenia, we undertook a double-blind comparison of low-dose fluphenazine decanoate (1.25 to 5.0 mg/2 wk) with the standard-dose regimen (12.5 to 50.0 mg/2 wk) in outpatient schizophrenics. For the first 126 patients studied, cumulative relapse rates at one year for the low dose were 56% and for the standard dose 7%, a significant difference. Despite the fact that very little dyskinetic symptomatology developed in the sample as a whole, the low-dose treatment appeared to have a significant advantage in producing fewer early signs of tardive dyskinesia. Severity of relapse and total cumulative dosage were also considered.
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Citations
Cites
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A Diagnostic Interview: The Schedule for Affective Disorders and Schizophrenia
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A RATING SCALE FOR EXTRAPYRAMIDAL SIDE EFFECTS
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A Controlled Trial of Social Intervention in the Families of Schizophrenic Patients
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Tardive Dyskinesia: Prevalence and Risk Factors, 1959 to 1979
Kane, J. M. (1982) · Archives of General Psychiatry · doi:10.1001/archpsyc.1982.04290040069010 · Cited by 656
Self-citationDrug and Sociotherapy in the Aftercare of Schizophrenic Patients: II. Two-Year Relapse Rates
Hogarty, G. E. (1974) · Archives of General Psychiatry · doi:10.1001/archpsyc.1974.01760170005001 · Cited by 573
Drug and Family Therapy in the Aftercare of Acute Schizophrenics
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Cited by
Symptom Monitoring in the Rehabilitation of Schizophrenic Patients
Lukoff, D., Liberman, R. P., & Nuechterlein, K. H. (1986) · Schizophrenia Bulletin · doi:10.1093/schbul/12.4.578 · Cited by 621
Multiple-Family Groups and Psychoeducation in the Treatment of Schizophrenia
McFarlane, W. R. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950200069016 · Cited by 560
Dose Response and Dose Equivalence of Antipsychotics
Davis, J. M., & Chen, N. (2004) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000117422.05703.ae · Cited by 358
Birchwood, M., Smith, J., Macmillan, F., Hogg, B., Prasad, R., Harvey, C., & Bering, S. (1989) · Psychological Medicine · doi:10.1017/s0033291700024247 · Cited by 334
Falkai, P., Wobrock, T., Lieberman, J., Glenthoj, B., Gattaz, W. F., Möller, H.-J., WFSBP Task Force on Treatment Guide, Falkai, P., Wobrock, T., Lieberman, J., et al. (2006) · The World Journal of Biological Psychiatry · doi:10.1080/15622970500483177 · Cited by 331
Metadata
- Authors
- Kane, J. M.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 1983-08-01
- Volume
- 40
- Issue
- 8
- Pages
- 893
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2012190810
- Cited by
- 273
- References
- 23
- FWCI
- 9.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kane, J. M. (1983). Low-Dose Neuroleptic Treatment of Outpatient Schizophrenics: I. Preliminary Results for Relapse Rates. Archives of General Psychiatry. https://doi.org/10.1001/archpsyc.1983.01790070083010
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.