The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Leukocyte Responses to Injury
Abstract
Injury elicits a response from all cells of the immune system in which cytokines and other metabolic products of activated leukocytes can act either beneficially to provide for enhanced host resistance or deleteriously to depress the function of remote organs and cause what has been termed systemic inflammation. These at times antithecal responses of leukocytes that appear to integrate postinjury changes in the neuroendocrine, immune, and coagulation systems have been implicated as principal causative factors in multiple systems organ failure. Numerous investigators have evaluated a variety of therapeutic agents to prevent and control infection by restoring leukocyte function, while others have evaluated antagonists and monoclonal antibodies as a means of controlling the exaggerated and persistent actions of leukocytes and cytokines caused by systemic inflammation. The redundancies of the cell populations and the cytokines and other metabolites produced by the cells predictably limit the effectiveness of any single agent and make clinical evaluation of such agents difficult.
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“Successful repair of injured tissues requires diverse interactions among different cells, biochemical mediators, and the cellular microenvironment47–49.”
From Neuropeptides Substance P and Calcitonin Gene Related Peptide Accelerate the Development and Fibrogenesis of Endometriosis (2019) · cites this paper as [48]
Citations
Cites
PECAM-1 is required for transendothelial migration of leukocytes.
Müller, W. A., Weigl, S. A., Deng, X., & Phillips, D. M. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.178.2.449 · Cited by 1,151
Nathan, C. (1987) · Journal of Clinical Investigation · doi:10.1172/jci113241 · Cited by 791
Signal transduction and cytoskeletal activation in the neutrophil.
Omann, G. M., Allen, R. A., Bokoch, G., Painter, R. G., Traynor, A. E., & Sklar, L. A. (1987) · Physiological Reviews · doi:10.1152/physrev.1987.67.1.285 · Cited by 280
Establishing optimal lymphocyte gates for immunophenotyping by flow cytometry
Loken, M. R., Brosnan, J. M., Bach, B. A., & Ault, K. A. (1990) · Cytometry · doi:10.1002/cyto.990110402 · Cited by 263
Wright, S. D., Reddy, P. A., Jong, M. T. C., & Erickson, B. W. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.7.1965 · Cited by 161
Enhancement of Neutrophil Function as a Result of Prior Exposure to Chemotactic Factor
Epps, D. E. V., & Garcia, M. L. (1980) · Journal of Clinical Investigation · doi:10.1172/jci109841 · Cited by 159
Cortisol and Corticotrophin in Burned Patients
Vaughan, G. M., BECKER, R. A., Allen, J. P., Goodwin, C. W., Pruitt, B. A., & Mason, A. D. (1982) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-198204000-00001 · Cited by 158
Mileski, W. J., Winn, R. K., Vedder, N. B., Pohlman, T. H., Harlan, J. M., & Rice, C. L. (1990) · PubMed · Cited by 155
Neutrophil Activation in Thermal Injury as Assessed by Increased Expression of Complement Receptors
Moore, F. D., Davis, C. F., Rodrick, M. L., Mannick, J. A., & Fearon, D. T. (1986) · New England Journal of Medicine · doi:10.1056/nejm198604103141503 · Cited by 148
Moss, N. M., Gough, D. B., Jordan, A., Grbic, J. T., Wood, J. J., Rodrick, M. L., & Mannick, J. A. (1988) · PubMed · Cited by 137
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Pathophysiology of the burn wound and pharmacological treatment. The Rudi Hermans Lecture, 1995
Arturson, G. (1996) · Burns · doi:10.1016/0305-4179(95)00153-0 · Cited by 194
The NO cascade, eNOS location, and microvascular permeability
Durán, W. N., Breslin, J. W., & Sánchez, F. A. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq139 · Cited by 191
Schäffer, M. R., Beiter, T., Becker, H. D., & Hunt, T. K. (1998) · Archives of Surgery · doi:10.1001/archsurg.133.10.1107 · Cited by 185
Laparoscopic-assisted vs. open surgery for colorectal cancer
Hewitt, P., Ip, S. M., Kwok, S. P., Somers, S. S., Li, K., Leung, K. L., Lau, W. Y., & LI, A. K. C. (1998) · Diseases of the Colon & Rectum · doi:10.1007/bf02235376 · Cited by 160
Decreased Mortality of Severe Acute Pancreatitis After Proximal Cytokine Blockade
Norman, J. G., Franz, M., Fink, G. W., Messina, J. L., Fabri, P. J., Gower, W. R., & Carey, L. C. (1995) · Annals of Surgery · doi:10.1097/00000658-199506000-00002 · Cited by 143
Metadata
- Authors
- Cioffi, W. G.
- Affiliations
- United States Army Institute of Surgical Research (US)
- Corresponding author
- Cioffi, William G.
- ORCID
- Cioffi, William G.
- Venue
- Archives of Surgery
- Publisher
- American Medical Association (AMA)
- Published
- 1993-11-01
- Volume
- 128
- Issue
- 11
- Pages
- 1260
- ISSN
- 0004-0010 (ISSN-L)
- OpenAlex
- W2066356532
- Cited by
- 71
- References
- 76
- Citations by year
- 2022: 1 · 2021: 1 · 2020: 2 · 2019: 3 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 3.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Surgery (publishedVersion)
- PubMed (publishedVersion)
- Defense Technical Information Center (DTIC) (submittedVersion)
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
- Life Sciences › Immunology and Microbiology › Immunology › Inflammation biomarkers and pathways
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Keywords
- systemic inflammation, multiple organ failure, cytokines, leukocyte activation, neuroendocrine-immune interaction, coagulation, infection control, monoclonal antibodies, cytokine antagonists, host resistance
- MeSH terms
- Antibodies, Monoclonal, B-Lymphocytes, Blood Coagulation, Chemotaxis, Leukocyte, Complement Activation, Granulocytes, Humans, Immunity, Innate, Infections, Inflammation, Leukocytes, Multiple Organ Failure, Neurosecretory Systems, Oxidation-Reduction, T-Lymphocytes, Wounds and Injuries, Lymphocyte Subsets, Cytokines
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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