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Posterior Subcapsular Cataracts Induced by Corticosteroids in Patients with Rheumatoid Arthritis

Black, Roger L.·1960·JAMA

Abstract

POSTERIOR subcapsular cataracts (PSC) are generally associated with exposure to toxic agents, posterior intraocular disease, ionizing radiation, or blunt trauma. As a rule these lenticular lesions are differentiated from senile cataracts by their location and appearance on slit lamp examination. The discovery of PSC, in the absence of any of the above etiologic factors, in four rheumatoid arthritis patients who were receiving prolonged administration of synthetic corticosteroids prompted a careful review and examination of rheumatoid arthritis patients available for study between June, 1959, and April, 1960. This survey revealed that 39% of patients with rheumatoid arthritis who had received long-term corticosteroid therapy developed PSC, whereas those who had not were free of this type of lenticular opacity. This ocular lesion, to date, has been relatively benign and has not caused severe impairment of vision. Since formation of PSC has not been described previously as one of the adverse effects of

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Metadata

Authors
Black, R. L.
Venue
JAMA
Published
1960-09-10
Volume
174
Issue
2
Pages
166
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W2019636120
Cited by
386
References
0
FWCI
22.79
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Posterior Subcapsular Cataracts Induced by Corticosteroids in Patients with Rheumatoid Arthritis. https://app.cochat.ai/papers/10.1001/jama.1960.63030020005014
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Black, R. L. (1960). Posterior Subcapsular Cataracts Induced by Corticosteroids in Patients with Rheumatoid Arthritis. JAMA. https://doi.org/10.1001/jama.1960.63030020005014

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.