The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Induction of Ovulation with MRL/41: Preliminary Report
Abstract
MRL/41, an analogue of the nonsteroid estrogen, chlorotrianisene, was evaluated in the human female because it was shown to possess pituitary gonadotropin-inhibiting and antifecundity properties in rats. Although structurally related to a hormone-like chemical agent, this compound does not exhibit estrogenic, progestogenic, or androgenic activity in the human. Studies with this drug were initiated primarily because of its potential as an antifertility agent. Contrary to expectations, some unsuspected and interesting biological activities were observed, one of which was the induction of ovulatorytype menses in amenorrheic anovulatory females.
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“Clomiphene citrate has been widely used in the treatment of infertility since its introduction into clinical practice in the 1960s (1).”
From A randomized double-blind comparison of the effects of clomiphene citrate and the aromatase inhibitor letrozole on ovulatory function in normal women (2002) · cites this paper as [1]
Citations
Cites
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Rakoff, A. E. (1953) · Fertility and Sterility · doi:10.1016/s0015-0282(16)31323-1 · Cited by 18
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« Selective estrogen receptor modulators » (SERM)
Chabbert‐Buffet, N., Thomin, A., Ouzounian, S., & Daraï, É. (2015) · doi:10.1016/s0246-1064(15)65065-4
2 Clomiphene Citrate in the Treatment of Male Infertility
Schellen, A. M. C. M. (1982)
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« Selective estrogen receptor modulators » (SERM)
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Metadata
- Authors
- Greenblatt, R. B.
- Corresponding author
- Greenblatt, Robert B.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1961-10-14
- Volume
- 178
- Issue
- 2
- Pages
- 101
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2068435339
- Cited by
- 343
- References
- 4
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 9 · 2021: 4 · 2020: 6 · 2019: 8 · 2018: 2 · 2017: 5 · 2016: 5 · 2015: 5 · 2014: 9 · 2013: 10 · 2012: 6
- FWCI
- 21.92
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Keywords
- ovulation induction, amenorrhea, anovulation, antifertility agents, gonadotropin suppression, menstrual induction
- MeSH terms
- Female, Humans, Ovulation, Stilbenes
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