Cited by 914Genetic Associations and EpidemiologyGenetics and Physical PerformanceObesity, Physical Activity, Diet

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A Twin Study of Human Obesity

Stunkard, Albert J.·1986·JAMA: The Journal of the American Medical Association

DOI 10.1001/jama.1986.03380010055024

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Abstract

Height, weight, and body mass index (BMI) were assessed in a sample of 1974 monozygotic and 2097 dizygotic male twin pairs. Concordance rates for different degrees of overweight were twice as high for monozygotic twins as for dizygotic twins. Classic twin methods estimated a high heritability for height, weight, and BMI, both at age 20 years (.80, .78, and .77, respectively) and at a 25-year follow-up (.80, .81, and .84, respectively). Height, weight, and BMI were highly correlated across time, and a path analysis suggested that the major part of that covariation was genetic. These results are similar to those of other twin studies of these measures and suggest that human fatness is under substantial genetic control.

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Statistical principles in experimental design.
Winer, B. J. (1962) · McGraw-Hill Book Company · doi:10.1037/11774-000 · Cited by 27,137
Introduction to Quantitative Genetics.
Edwards, A. W. F., & Falconer, D. S. (1982) · Biometrics · doi:10.2307/2529912 · Cited by 21,447
Indices of relative weight and obesity
Keys, A. B., Fidanza, F., Karvonen, M. J., Kimura, N., & TAYLOR, H. L. (1972) · Journal of Chronic Diseases · doi:10.1016/0021-9681(72)90027-6 · Cited by 2,085
An Adoption Study of Human Obesity
Stunkard, A. J., Sørensen, T. I. A., Hanis, C., Teasdale, T. W., Chakraborty, R., Schull, W. J., & Schulsinger, F. (1986) · New England Journal of Medicine · doi:10.1056/nejm198601233140401 · Cited by 1,318
Self-citation
COMPARISON OF SELF-REPORTED AND MEASURED HEIGHT AND WEIGHT
Palta, M., Prineas, R. J., Berman, R., & Hannan, P. J. (1982) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113294 · Cited by 641
First Course in Population Genetics
Li, C. C. (1976) · Medical Entomology and Zoology · Cited by 535
Evidence of Genetic Predisposition to Alcoholic Cirrhosis and Psychosis: Twin Concordances for Alcoholism and Its Biological End Points by Zygosity among Male Veterans
Hrubec, Z., & Omenn, G. S. (1981) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1981.tb04890.x · Cited by 464
Twins: A Study of Heredity and Environment.
Ciocco, A., NEWMAN, H. H., Freeman, F. N., & Holzinger, K. J. (1937) · Journal of the American Statistical Association · doi:10.2307/2279415 · Cited by 453
THE NHLBI TWIN STUDY OF CARDIOVASCULAR DISEASE RISK FACTORS: METHODOLOGY AND SUMMARY OF RESULTS
Feinleib, M., Garrison, R. J., Fabsitz, R. R., Christian, J. C., Hrubec, Z., Borhani, N. O., Kannel, W. B., Rosenman, R. H., Schwartz, J. T., & Wagner, J. O. (1977) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112464 · Cited by 449
Trends in Fatness and the Origins of Obesity
Garn, S. M., Clark, D. C., Lowe, C. U., Forbes, G. B., Garn, S. M., Owen, G. M., Smith, N. J., Weil, W. B., Nichaman, M. Z., Johansen, E., et al. (1976) · PEDIATRICS · doi:10.1542/peds.57.4.443 · Cited by 421

Show all 29 references

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Karunakaran, D., Turner, A. W., Duchez, A., Soubeyrand, S., Rasheed, A., Smyth, D. R., Cook, D. P., Nikpay, M., Kandiah, J. W., Pan, C., et al. (2020) · Nature Metabolism · doi:10.1038/s42255-020-00279-2 · Cited by 58
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Cozzolino, D., Sessa, G., Salvatore, T., Sasso, F. C., Giugliano, D., Lefèbvre, P. J., & Torella, R. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.2.8636293 · Cited by 58
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Self-citation
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Self-citation
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Genetic and early environmental components in sociodemographic influences on adult body fatness.
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Self-citation
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Body weight in the Finnish Twin Cohort
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Pediatricians’ Perceptions and Practices Regarding Childhood Obesity
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Diet and cardiovascular disease prevention: What works?
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Dietary Therapy for Obesity: An Emperor With No Clothes
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Authors: Stunkard, A. J.
Corresponding author: Stunkard, Albert J.
Venue: JAMA: The Journal of the American Medical Association
Publisher: American Medical Association (AMA)
Published: 1986-07-04
Volume: 256
Issue: 1
Pages: 51
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.1986.03380010055024
OpenAlex: W2001913879
Cited by: 912
References: 29
Citations by year: 2026: 3 · 2025: 13 · 2024: 11 · 2023: 19 · 2022: 17 · 2021: 28 · 2020: 18 · 2019: 27 · 2018: 21 · 2017: 32 · 2016: 37 · 2015: 44 · 2014: 39 · 2013: 53 · 2012: 46
FWCI: 9.37
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k05mh000245-13)
National Institute of Mental Health (5-KO5-MH-00245)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Physical Performance
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords: obesity, heritability, monozygotic twins, dizygotic twins, body mass index, height, weight, concordance rate, path analysis
MeSH terms: Adult, Body Height, Body Weight, Diseases in Twins, Follow-Up Studies, Humans, Male, Mathematics, Military Personnel, National Academy of Sciences, U.S., Obesity, Registries, Twins, Dizygotic, Twins, Monozygotic, United States

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A Twin Study of Human Obesity

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