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Cited by 348

The DOI matches its Crossref record.

Enhancing the Outcomes of Low-Birth-Weight, Premature Infants: A Multisite, Randomized Trial

·1990·JAMA

Abstract

The Infant Health and Development Program is an eight-site clinical trial designed to evaluate the efficacy of a comprehensive early intervention in reducing the developmental and health problems of low-birth-weight (less than or equal to 2500 g) premature (less than or equal to 37 weeks) infants. Nine hundred eighty-five infants, stratified by site and weight (less than or equal to 2000 g or 2001 to 2500 g), were randomly assigned to receive an educational curriculum focused on child development, as well as family support and pediatric follow-up, or only pediatric follow-up. At corrected age 36 months, the intervention group had significantly higher mean IQ scores than the follow-up group (mean difference in the heavier group was 13.2 and in the lighter group 6.6), significantly fewer maternally reported behavior problems, and a small, but statistically significant, increase in maternally reported minor illnesses for the lighter-birth-weight group only, with no difference in serious health conditions.

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Metadata

Venue
JAMA
Published
1990-06-13
Volume
263
Issue
22
Pages
3035
ISSN
  • 0002-9955 (ISSN-L)
  • 0098-7484
OpenAlex
W4230185873
Cited by
348
References
0
FWCI
23.54
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Enhancing the Outcomes of Low-Birth-Weight, Premature Infants: A Multisite, Randomized Trial. https://app.cochat.ai/papers/10.1001/jama.1990.03440220059030
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Enhancing the Outcomes of Low-Birth-Weight, Premature Infants: A Multisite, Randomized Trial. (1990). JAMA. https://doi.org/10.1001/jama.1990.03440220059030

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.