The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Detection of At-Risk Pregnancy by Means of Highly Sensitive Assays for Thyroid Autoantibodies
Abstract
We screened 552 women who presented to their obstetrician in the first trimester of pregnancy using highly sensitive enzyme-linked immunosorbent assays for the presence of thyroglobulin and thyroid peroxidase autoantibodies and found an incidence of positivity of 19.6%. The tendency to secrete detectable levels of thyroid autoantibodies was significantly correlated with an increased rate of miscarriage. Thyroid autoantibody-positive women miscarried at a rate of 17%, compared with 8.4% for the autoantibody-negative women. Individual levels of thyroglobulin and thyroid peroxidase autoantibodies were similarly related to this increased miscarriage rate, with no evidence of autoantibody specificity in the relationship. Furthermore, the increase in miscarriages could not be explained by differences in thyroid hormone levels, the presence of cardiolipin autoantibodies, maternal age, gestational age at the time of maternal entry into the study, or previous obstetric history. We conclude that thyroid autoantibodies are an independent marker of "at-risk" pregnancy.
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Cites
Incidence of early loss of pregnancy
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Cited by
Stagnaro-Green, A., Abalovich, M., Alexander, E., Azizi, F., Mestman, J., Negro, R., Nixon, A., Pearce, E. N., Soldin, O. P., Sullivan, S., et al. (2011) · Thyroid · doi:10.1089/thy.2011.0087 · Cited by 2,942
Self-citationAlexander, E. K., Pearce, E. N., Brent, G. A., Brown, R. S., Chen, H., Dosiou, C., Grobman, W. A., Laurberg, P., Lazarus, J. H., Mandel, S. J., et al. (2017) · Thyroid® · doi:10.1089/thy.2016.0457 · Cited by 2,731
Garber, J. R., Cobin, R. H., Gharib, H., Hennessey, J. V., Klein, I., Mechanick, J. I., Pessah-Pollack, R., Singer, P. A., & Woeber, K. A. (2012) · Endocrine Practice · doi:10.4158/ep12280.gl · Cited by 1,567
Glinoer, D. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.3.0300 · Cited by 1,364
Garber, J. R., Cobin, R. H., Gharib, H., Hennessey, J. V., Klein, I., Mechanick, J. I., Pessah-Pollack, R., Singer, P. A., & Woeber for the American Association, K. A. (2012) · Thyroid · doi:10.1089/thy.2012.0205 · Cited by 1,053
Chronic Autoimmune Thyroiditis
Dayan, C. M., & Daniels, G. H. (1996) · New England Journal of Medicine · doi:10.1056/nejm199607113350206 · Cited by 904
Thangaratinam, S., Tan, A., Knox, E., Kilby, M. D., Franklyn, J., & Coomarasamy, A. (2011) · BMJ · doi:10.1136/bmj.d2616 · Cited by 604
van den Boogaard, E., Vissenberg, R., Land, J. A., van Wely, M., van der Post, J. A. M., Goddijn, M., & Bisschop, P. H. (2011) · Human Reproduction Update · doi:10.1093/humupd/dmr024 · Cited by 528
Pregnancy in patients with mild thyroid abnormalities: maternal and neonatal repercussions
GLINOER, D., SOTO, M. F., BOURDOUX, P., LEJEUNE, B., DELANGE, F., LEMONE, M., KINTHAERT, J., ROBIJN, C., GRUN, J.-P., & NAYER, P. D. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-2-421 · Cited by 379
The role of thyroid autoimmunity in fertility and pregnancy
Poppe, K., Velkeniers, B., & Glinoer, D. (2008) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0846 · Cited by 298
Impact of subclinical hypothyroidism in women with recurrent early pregnancy loss
Bernardi, L. A., Cohen, R. N., & Stephenson, M. D. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.07.1975 · Cited by 90
Bliddal, S., Feldt-Rasmussen, U., Rasmussen, Å. K., Kolte, A. M., Hilsted, L. M., Christiansen, O. B., Nielsen, C. H., & Nielsen, H. S. (2019) · Thyroid® · doi:10.1089/thy.2019.0077 · Cited by 63
Lata, K., Dutta, P., Sridhar, S., Rohilla, M., Srinivasan, A., Prashad, G. R. V., Shah, V. N., & Bhansali, A. (2013) · Endocrine Connections · doi:10.1530/ec-13-0012 · Cited by 60
Biochemical Testing in Thyroid Disorders
Esfandiari, N. H., & Papaleontiou, M. (2017) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2017.04.002 · Cited by 50
Metadata
- Authors
- Stagnaro-Green, A.
- Venue
- JAMA: The Journal of the American Medical Association
- Publisher
- American Medical Association (AMA)
- Published
- 1990-09-19
- Volume
- 264
- Issue
- 11
- Pages
- 1422
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2015079707
- Cited by
- 494
- References
- 2
- FWCI
- 4.18
- Type
- journal article
- Language
- en
- Open access
- closed
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