Cited by 697Mental Health Treatment and AccessHealth Systems, Economic Evaluations, Quality of LifeAging, Health, and Disability

The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.

Depressive Symptoms and the Cost of Health Services in HMO Patients Aged 65 Years and Older: A 4-Year Prospective Study

Unützer, Jürgen·1997·JAMA

DOI 10.1001/jama.1997.03540440052032

Open this paper in CoChat — free account

Abstract

OBJECTIVE: To examine whether depressive symptoms in older adults contribute to increased cost of general medical services. DESIGN: A 4-year prospective cohort study. SETTING: Four primary care clinics of a large staff-model health maintenance organization (HMO) in Seattle, Wash. PATIENTS: A total of 5012 Medicare enrollees older than 65 years were invited to participate in the study; 2558 subjects (51%) were successfully enrolled. Non-participants were somewhat older and had a higher level of chronic medical illness. MAIN OUTCOME MEASURES: Depressive symptoms as measured by the Center for Epidemiological Studies Depression scale, which was administered as part of a mail survey at baseline, at 2 years, and at 4 years; and total cost of medical services from the perspective of the HMO. Data were obtained from the cost accounting system of the HMO. RESULTS: In this cohort of older adults, depressive symptoms were common, persistent, and associated with a significant increase in the cost of general medical services. This increase was seen for every component of health care costs and was not accounted for by an increase in specialty mental health care. The increase in health care costs remained significant after adjusting for differences in age, sex, and chronic medical illness. CONCLUSIONS: Depressive symptoms in older adults are associated with a significant increase in the cost of medical services, even after adjusting for the severity of chronic medical illness.

Integrity signals

Registry

Crossref · 10.1001/jama.1997.03540440052032

Cites

66 of 66 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
Maximum Likelihood Estimation of Misspecified Models
White, H. (1983) · Econometrica · doi:10.2307/1912004 · Cited by 3,705
Assessing depressive symptoms in five psychiatric populations: a validation study.
Weissman, M., Sholomskas, D., Pottenger, M., Prusoff, B., & Locke, B. Z. (1977) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112455 · Cited by 2,232
Depression Following Myocardial Infarction
Frasure‐Smith, N. (1993) · JAMA · doi:10.1001/jama.1993.03510150053029 · Cited by 2,039
Economic burden of depression
Greenberg, P. E., Stiglin, L. E., Finkelstein, S. N., & Berndt, E. R. (1994) · PharmacoResources · doi:10.1007/bf03289581 · Cited by 975
A chronic disease score from automated pharmacy data
Korff, M. V., Wagner, E. H., & Saunders, K. W. (1992) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(92)90016-g · Cited by 962
Functioning and Well-being Outcomes of Patients With Depression Compared With Chronic General Medical Illnesses
Hays, R. D. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950130011002 · Cited by 835
Utilization of Health and Mental Health Services
Shapiro, S. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1984.01790210053007 · Cited by 816
Use of a self-report symptom scale to detect depression in a community sample
Myers, J. K., & Weissman, M. M. (1980) · American Journal of Psychiatry · doi:10.1176/ajp.137.9.1081 · Cited by 777
Service utilization and social morbidity associated with depressive symptoms in the community
Johnson, J. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03480110054033 · Cited by 726

Show all 65 references

Sorted by citations

Items 201–300 of 695

Differences in demographic composition and in work, social, and functional limitations among the populations with unipolar depression and bipolar disorder: results from a nationally representative sample
Shippee, N. D., Shah, N. D., Williams, M. D., Moriarty, J. P., Frye, M. A., & Ziegenfuss, J. Y. (2011) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-9-90 · Cited by 68
Suboptimal Antidepressant Use in the Elderly
Wang, P. S., Schneeweiß, S., Brookhart, M. A., Glynn, R. J., Mogun, H., Patrick, A. R., & Avorn, J. (2005) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000155819.67209.e5 · Cited by 67
Age and risk for depression among the elderly: a meta-analysis of the published literature
Zhao, K., Huang, C.-Q., Xiao, Q., Gao, Y., Liu, Q., Wang, Z., Li, Y., & Xie, Y. (2012) · CNS Spectrums · doi:10.1017/s1092852912000533 · Cited by 66
Poor mental health status and its associations with demographic characteristics and chronic diseases in Chinese elderly
Wang, S., Li, B., Ungvari, G. S., Ng, C. H., Chiu, H. F. K., Kou, C., Liu, Y., Tao, Y., Wu, Y., Fu, Y., et al. (2016) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-016-1271-y · Cited by 68
Longitudinal Association Between Sleep Duration and Depressive Symptoms in Chinese Elderly
Jing, R., Xu, T., Rong, H., Lai, X., & Fang, H. (2020) · Nature and Science of Sleep · doi:10.2147/nss.s269992 · Cited by 67
Cognitive function and risk for depression in old age: a meta-analysis of published literature
Huang, C.-Q., Wang, Z., Li, Y., Xie, Y.-Z., & Liu, Q. (2010) · International Psychogeriatrics · doi:10.1017/s1041610210000049 · Cited by 63
Translating Research Into Practice: Case Study Of A Community-Based Dementia Caregiver Intervention
Mittelman, M. S., & Bartels, S. J. (2014) · Health Affairs · doi:10.1377/hlthaff.2013.1334 · Cited by 64
Common mental disorders and use of general health services: a review of the literature on population‐based studies
Koopmans, G. T., Donker, M. C. H., & Rutten, F. (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00496.x · Cited by 63
Prevalence of depression, anxiety and stress disorders in elderly people residing in Khoy, Iran (2014-2015)
Babazadeh, T., Sarkhoshi, R., Bahadori, F., Moradi, F., Shariat, F., & Sherizadeh, Y. (2016) · Journal of Analytical Research in Clinical Medicine · doi:10.15171/jarcm.2016.020 · Cited by 64
Major Depressive Disorder in the African American Population
Bailey, R. K., Patel, M., Barker, N. C., Ali, S., & Jabeen, S. (2011) · Journal of the National Medical Association · doi:10.1016/s0027-9684(15)30380-1 · Cited by 66
The natural history of late-life depression: results from the Amsterdam Study of the Elderly (AMSTEL)
Schoevers, R. A. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00060-5 · Cited by 64
Natural course of depressive symptoms in late life. An 8-year population-based prospective study
Luppa, M., Luck, T., König, H., Angermeyer, M. C., & Riedel-Heller, S. G. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.05.009 · Cited by 62
Does depression predict the use of urgent and unscheduled care by people with long term conditions? A systematic review with meta-analysis
Dickens, C. M., Katon, W. J., Blakemore, A., Khara, A., McGowan, L., Tomenson, B., Jackson, J., Walker, L., & Guthrie, E. (2012) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2012.08.018 · Cited by 64
Depression as a Risk Factor for Nursing Home Admission Among Older Individuals
Harris, Y. (2006) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2006.06.005 · Cited by 63
The safety and tolerability of duloxetine in depressed elderly patients with and without medical comorbidity: Duloxetine in elderly patients with depression
Wise, T. N., Wiltse, C. G., Iosifescu, D. V., Sheridan, M., Xu, J. Y., & Raskin, J. (2007) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2007.01476.x · Cited by 62
Attitudes, Knowledge, and Behavior of Family Physicians Regarding Depression in Late Life
Gallo, J. J. (1999) · Archives of Family Medicine · doi:10.1001/archfami.8.3.249 · Cited by 62
Tinker, tailor, soldier, patient: work attributes and depression disparities among young adults
Zimmerman, F. J., Christakis, D., & Stoep, A. V. (2003) · Social Science & Medicine · doi:10.1016/s0277-9536(03)00410-6 · Cited by 61
Treatment of Depression in Older Primary Care Patients in Health Maintenance Organizations
Bartels, S. J., Horn, S. D., Sharkey, P. D., & Levine, K. J. (1997) · The International Journal of Psychiatry in Medicine · doi:10.2190/vkbr-1ar6-9nbd-0n25 · Cited by 61
Functional Impairment and Co-occurring Psychiatric Disorders in Medically Hospitalized Men
Booth, B. M., Blow, F. C., & Cook, C. A. L. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.14.1551 · Cited by 59
Depression in Assisted Living Is Common and Related to Physical Burden
Watson, L. C., Lehmann, S. W., Mayer, L. S., Samus, Q. M., Baker, A. S., Brandt, J., Steele, C., Rabins, P. V., Rosenblatt, A., & Lyketsos, C. G. (2006) · American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000218698.80152.79 · Cited by 59
The relationship between depressive symptoms, health service consumption, and prognosis after acute myocardial infarction: a prospective cohort study
Kurdyak, P. A., Gnam, W., Goering, P. N., Chong, A. S., & Alter, D. A. (2008) · BMC Health Services Research · doi:10.1186/1472-6963-8-200 · Cited by 59
Excess health care costs of late-life depression – Results of the AgeMooDe study
Bock, J., Brettschneider, C., Weyerer, S. B., Werle, J., Wagner, M., Maier, W., Scherer, M., Kaduszkiewicz, H., Wiese, B., Moor, L., et al. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.04.008 · Cited by 62
13 Year Follow Up of Morbidity, Mortality and Use of Health Services Among Elderly Depressed Patients and General Elderly Populations
Djernes, J. K., Gulmann, N. C., Foldager, L., Olesen, F., & Munk‐Jørgensen, P. (2011) · Australian & New Zealand Journal of Psychiatry · doi:10.3109/00048674.2011.589368 · Cited by 58
Differences in Professional and Informal Help Seeking among Older African Americans, Black Caribbeans and Non-Hispanic Whites
Woodward, A. T., Chatters, L. M., Taylor, R., Neighbors, H. W., & Jackson, J. (2010) · Journal of the Society for Social Work and Research · doi:10.5243/jsswr.2010.10 · Cited by 61
Unpacking Collaborative Care for Depression: Examining Two Essential Tasks for Implementation
Bao, Y., Druss, B. G., Jung, H., Chan, Y.-F., & Unützer, J. (2015) · Psychiatric Services · doi:10.1176/appi.ps.201400577 · Cited by 58
Unmet Needs for Services for Older Adults With Mental Illness: Comparison of Views of Different Stakeholder Groups
Palinkas, L. A., Criado, V., Fuentes, D., Shepherd, S., Milian, H., Folsom, D. P., & Jeste, D. V. (2007) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3180381505 · Cited by 57
Health care costs of depression in patients diagnosed with cancer
Mausbach, B. T., Yeung, P., Bos, T., & Irwin, S. A. (2018) · Psycho-Oncology · doi:10.1002/pon.4716 · Cited by 57
Development and preliminary evaluation of a telephone-based coping skills training intervention for survivors of acute lung injury and their informal caregivers
Cox, C. E., Porter, L. S., Hough, C. L., White, D. B., Kahn, J. M., Carson, S. S., Tulsky, J. A., & Keefe, F. J. (2012) · Intensive Care Medicine · doi:10.1007/s00134-012-2567-3 · Cited by 55
Reduction in Symptoms for Homebound Patients Receiving Home-Based Primary and Palliative Care
Ornstein, K. A., Wajnberg, A., Kaye‐Kauderer, H., Winkel, G. H., DeCherrie, L. V., Zhang, M., & Soriano, T. A. (2013) · Journal of Palliative Medicine · doi:10.1089/jpm.2012.0546 · Cited by 56
Depression and related factors in older people in China: a systematic review
Chen, Y., Hicks, A., & While, A. (2011) · Reviews in Clinical Gerontology · doi:10.1017/s0959259811000219 · Cited by 56
Geriatric Depression, Antidepressant Treatment, and Healthcare Utilization in a Health Maintenance Organization
Fischer, L. R., Wei, F., Rolnick, S. J., Jackson, J., Rush, W. A., Garrard, J. M., Nitz, N., & Luepke, L. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50063.x · Cited by 56
Serious Psychological Distress and Mental Health Service Use Among Community-Dwelling Older U.S. Adults
Han, B., Gfroerer, J., Colpe, L. J., Barker, P. R., & Colliver, J. D. (2011) · Psychiatric Services · doi:10.1176/ps.62.3.pss6203_0291 · Cited by 56
Depression and frequent attendance in elderly primary care patients
Menchetti, M., Cevenini, N., Ronchi, D. D., Quartesan, R., & Berardi, D. (2006) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2005.10.007 · Cited by 55
How Much Does Quality Mental Health Care Profit Employers?
Langlieb, A. M., & Kahn, J. P. (2005) · Journal of Occupational and Environmental Medicine · doi:10.1097/01.jom.0000177124.60460.25 · Cited by 56
Double-blind, placebo-controlled evaluation of extended-release bupropion in elderly patients with major depressive disorder
Hewett, K., Chrzanowski, W., Jokinen, R., Felgentreff, R., Rk, S., Gee, M., Wightman, D., O'Leary, M., Millen, L., Leon, M., et al. (2009) · Journal of Psychopharmacology · doi:10.1177/0269881108100254 · Cited by 56
Depressive symptoms and lymphocyte proliferation in older adults.
McGuire, L. M., Kiecolt‐Glaser, J. K., & Glaser, R. (2002) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.111.1.192 · Cited by 54
Severity of child maltreatment, pain complaints and medical utilization among women
Arnow, B. A., Hart, S. L., Hayward, C., Dea, R., & Taylor, C. B. (2000) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(00)00037-6 · Cited by 54
Measurable outcomes in psychiatric disorders: Remission as a marker of wellness
McIntyre, R. S., Fallu, A., & Konarski, J. Z. (2006) · Clinical Therapeutics · doi:10.1016/j.clinthera.2006.11.007 · Cited by 52
Depressive symptoms predict mortality in elderly subjects with chronic heart failure
Testa, G., Cacciatore, F., Galizia, G., Della‐Morte, D., Mazzella, F., Gargiulo, G., Langellotto, A., Raucci, C., Ferrara, N., Rengo, F., et al. (2011) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.2011.02544.x · Cited by 53
Cerebrovascular Damage in Late-Life Depression Is Associated With Structural and Functional Abnormalities of Subcutaneous Small Arteries
Greenstein, A. S., Paranthaman, R., Burns, A. S., Jackson, A., Malik, R. A., Baldwin, R., & Heagerty, A. M. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.152801 · Cited by 53
Treating depression in older adults: challenges to implementing the recommendations of an expert panel.
Snowden, M. B., Steinman, L. E., & Frederick, J. (2008) · PubMed Central · Cited by 53
Can we trust depression screening instruments in healthy ‘old‐old’ adults?
Watson, L. C., Lewis, C. L., Kistler, C. E., Amick, H. R., & Boustani, M. A. (2004) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1082 · Cited by 53
Factors affecting the increased risk of physical inactivity among older people with depressive symptoms
Rosqvist, E., Heikkinen, E. M., Lyyra, T.-M., Hirvensalo, M. H., Kallinen, M., Leinonen, R., Rasinaho, M., Pakkala, I., & Rantanen, T. (2009) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2008.00798.x · Cited by 52
Collaborative Care for Depressed Patients With Chronic Medical Conditions: A Randomized Trial in Puerto Rico
Vera, M., Pérez-Pedrogo, C., Huertas, S. E., Reyes-Rabanillo, M. L., Juarbe, D., Huertas, A., Reyes‐Rodríguez, M. L., & Chaplin, W. F. (2010) · Psychiatric Services · doi:10.1176/ps.2010.61.2.144 · Cited by 58
Autonomous Neurobiological Pathways to Late-Life Major Depressive Disorder Clinical and Pathophysiological Implications
Kumar, A. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00331-1 · Cited by 52
Incremental Cost-effectiveness of Combined Therapy vs Medication Only for Youth With Selective Serotonin Reuptake Inhibitor–Resistant Depression
Lynch, F. L., Dickerson, J. F., Clarke, G. N., Vitiello, B., Porta, G., Wagner, K. D., Emslie, G. J., Asarnow, J. R., Keller, M. B., Birmaher, B. B., et al. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.9 · Cited by 54
Beyond Symptomatic Improvement
Langlieb, A. M., & Guico‐Pabia, C. J. (2010) · The Primary Care Companion to The Journal of Clinical Psychiatry · doi:10.4088/pcc.09r00826blu · Cited by 52
Reducing Costs of Acute Care for Ambulatory Care-sensitive Medical Conditions
Yoon, J., Yano, E. M., Altman, L., Cordasco, K. M., Stockdale, S. E., Chow, A., Barnett, P. G., & Rubenstein, L. V. (2012) · Medical Care · doi:10.1097/mlr.0b013e31824e3379 · Cited by 51
Cognitive Outcomes After Psychotherapeutic Interventions for Major Depression in Older Adults with Executive Dysfunction
Mackin, R. S., Nelson, J. C., Delucchi, K., Raue, P. J., Byers, A. L., Barnes, D. E., Satre, D. D., Yaffe, K. S., Alexopoulos, G. S., & Areán, P. A. (2013) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2013.11.002 · Cited by 51
Large Medical Databases, Population-Based Research, and Patient Confidentiality
Simon, G. E., Unützer, J., Young, B. E., & Pincus, H. A. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.11.1731 · Cited by 51
Geriatric Mental Health Services Research: Strategic Plan for an Aging Population: Report of the Health Services Work Group of the American Association for Geriatric Psychiatry
Soo Borson, B., Bartels, S. J., Colenda, C. C., Gottlieb, G. L., & Meyers, B. S. (2001) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200108000-00002 · Cited by 50
Depressive Symptoms and Circadian Activity Rhythm Disturbances in Community-Dwelling Older Women
Maglione, J. E., Ancoli-Israel, S., Peters, K. W., Paudel, M. L., Yaffe, K., Ensrud, K. E., Tranah, G. J., & Stone, K. L. (2014) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2012.09.003 · Cited by 49
Depression Increases Stroke Hospitalization Cost: An Analysis of 17,010 Stroke Patients in 2008 by Race and Gender
Husaini, B. A., Levine, R. S., Sharp, L., Cain, V. A., Novotny, M. L., Hull, P. C., Orum, G., Samad, Z., Sampson, U. K. A., & Moonis, M. (2013) · Stroke Research and Treatment · doi:10.1155/2013/846732 · Cited by 49
Network analysis of anxiety and depression in the functionally impaired elderly
Yang, T., Guo, Z., Cao, X., Zhu, X., Zhou, Q., Li, X., Wang, H., Wang, X., Wu, L., Wu, S., et al. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.1067646 · Cited by 51
Use of PASRR Programs to Assess Serious Mental Illness and Service Access in Nursing Homes
Linkins, K. W., Lucca, A. M., Housman, M. G., & Smith, S. A. (2006) · Psychiatric Services · doi:10.1176/appi.ps.57.3.325 · Cited by 48
Urinary incontinence is strongly associated with depression in middle-aged and older Korean women: Data from the Korean longitudinal study of ageing
Lim, Y.-M., Lee, S. R., Choi, E., Jeong, K., & Chung, H. W. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2017.11.017 · Cited by 48
Psychiatric Emergencies in the Elderly Population
Piechniczek‐Buczek, J. (2006) · Emergency Medicine Clinics of North America · doi:10.1016/j.emc.2006.01.008 · Cited by 48
From Establishing an Evidence-Based Practice to Implementation in Real-World Settings: IMPACT as a Case Study
Unützer, J., Powers, D., Katon, W. J., & Langston, C. A. (2005) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2005.09.001 · Cited by 48
Effectiveness research and implications for study design: sample size and statistical power
Sturm, R., Unützer, J., & Katon, W. J. (1999) · General Hospital Psychiatry · doi:10.1016/s0163-8343(99)00024-9 · Cited by 48
Diagnosis of late life depression: the view from primary care
Schwenk, T. L. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01389-6 · Cited by 47
Underlying Factors in the Association between Depressed Mood and Mobility Limitation in Older People
Hirvensalo, M. H., Sakari‐Rantala, R., Kallinen, M., Leinonen, R., Lintunen, T., & Rantanen, T. (2007) · Gerontology · doi:10.1159/000098416 · Cited by 46
Cognitive Impairment and its Associations with the Path of Illness in Affective Disorders
Daniel, B. D., Montali, A., Gerra, M. L., Innamorati, M., Girardi, P., Pompili, M., & Amore, M. (2013) · Journal of Psychiatric Practice · doi:10.1097/01.pra.0000432597.79019.e2 · Cited by 48
Community Participation and the Emergence of Late-Life Depressive Symptoms: Differences between Women and Men
Ahern, M. M., & HENDRYX, M. S. (2008) · Journal of Women s Health · doi:10.1089/jwh.2007.0752 · Cited by 46
Psychological outcomes of an outpatient pulmonary rehabilitation program in patients with chronic obstructive pulmonary disease
Kayahan, B., Karapolat, H., Atýntoprak, E., Atasever, A., & Öztürk, Ö. (2005) · Respiratory Medicine · doi:10.1016/j.rmed.2005.09.031 · Cited by 46
Cost-effectiveness of interventions for depressed Latinos.
Schoenbaum, M., Miranda, J. M., Sherbourne, C. D., Duan, N., & Wells, K. B. (2004) · PubMed · Cited by 46
Predictive factors of depressive symptoms of elderly patients with cancer receiving first‐line chemotherapy
Duc, S., Rainfray, M., Soubeyran, P., Fonck, M., Blanc, J., Ceccaldi, J., Cany, L., Brouste, V., & Mathoulin-Pélissier, S. (2017) · Psycho-Oncology · doi:10.1002/pon.4090 · Cited by 44
Naturalistic outcomes of minor and subsyndromal depression in older primary care patients
Lyness, J. M. (2008) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1982 · Cited by 45
Narrowing the Gap in Treatment of Depression
Harman, J. S., Mulsant, B. H., Kelleher, K. J., Schulberg, H. C., Kupfer, D. J., & Reynolds, C. F. (2001) · The International Journal of Psychiatry in Medicine · doi:10.2190/q3vy-t8v9-30ma-vc5c · Cited by 45
Improving Depressive Symptoms in Community-Dwelling Older Adults: A Psychosocial Intervention Using Life Review and Writing : Workshop Participants Experienced Reduced Depressive Symptoms, Supporting Further Use of and Research on This Easy-To-Implement Intervention .
Mastel‐Smith, B., McFARLANE, J. M., Sierpina, M., Malecha, A. T., & Haile, B. (2007) · Journal of Gerontological Nursing · doi:10.3928/00989134-20070501-04 · Cited by 44
Sertraline Versus Fluvoxamine in the Treatment of Elderly Patients With Major Depression
Rossini, D., Serretti, A., Franchini, L., Mandelli, L., Smeraldi, E., Ronchi, D. D., & Zanardi, R. (2005) · Journal of Clinical Psychopharmacology · doi:10.1097/01.jcp.0000177548.28961.e7 · Cited by 44
Detection of depression and anxiety disorders by home care nurses
Préville, M., Côté, G., Boyer, R., & Hébert, R. (2004) · Aging & Mental Health · doi:10.1080/13607860410001725009 · Cited by 44
Management of depression in older people with osteoarthritis: A systematic review
Yohannes, A., & Caton, S. (2010) · Aging & Mental Health · doi:10.1080/13607860903483094 · Cited by 61
Provisional diagnostic criteria for depression of Alzheimer’s disease: description and review
Olin, J. T., Schneider, L. S. S., Katz, I. R., Meyers, B. S., Alexopoulos, G. S., Breitner, J. C. S., BRUCE, M. L., Caine, E. D., Cummings, J. L., Devanand, D. P., et al. (2003) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.3.1.99 · Cited by 43
Non-psychiatric Physicians' Knowledge, Attitudes and Behavior Toward Depression
Liu, S.-I., Lu, R., & Lee, M. (2008) · Journal of the Formosan Medical Association · doi:10.1016/s0929-6646(09)60015-2 · Cited by 43
Evaluating Community-Based Programs for Dementia Caregivers: The Cost Implications of Adult Day Services
Gaugler, J. E., Zarit, S. H., Townsend, A. L., Stephens, M. P., & Greene, R. (2003) · Journal of Applied Gerontology · doi:10.1177/0733464802250049 · Cited by 43
Validation of a brief screening tool to detect depression in elderly ED patients
Fabacher, D. A., Raccio‐Robak, N., McErlean, M. A., Milano, P. M., & Verdile, V. P. (2002) · The American Journal of Emergency Medicine · doi:10.1053/ajem.2002.30103 · Cited by 43
Diffusion of New Generation Antidepressant Treatment Among Elderly Diagnosed With Depression
Sambamoorthi, U., Olfson, M., Walkup, J. T., & Crystal, S. (2003) · Medical Care · doi:10.1097/00005650-200301000-00019 · Cited by 42
Personalised treatment for older adults with cancer: The role of frailty assessment
O’Donovan, A., & Leech, M. (2020) · Technical Innovations & Patient Support in Radiation Oncology · doi:10.1016/j.tipsro.2020.09.001 · Cited by 45
Brief Interventions to Prevent Depression in Older Subjects: A Systematic Review of Feasibility and Effectiveness
Cole, M. G. (2008) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e318162f174 · Cited by 43
Direct costs associated with depressive symptoms in late life: a 4.5-year prospective study
Luppa, M., König, H., Heider, D., Leicht, H., Motzek, T., Schomerus, G., & Riedel-Heller, S. G. (2012) · International Psychogeriatrics · doi:10.1017/s1041610212001688 · Cited by 40
Economic Grand Rounds: The Myth of Medical Cost Offset
Sturm, R. (2001) · Psychiatric Services · doi:10.1176/appi.ps.52.6.738 · Cited by 42
Impact of Medicare Part D on Antidepressant Treatment, Medication Choice, and Adherence Among Older Adults With Depression
Donohue, J. M., Zhang, Y., Perera, S., Lave, J. R., Hanlon, J. T., Men, A., & Reynolds, C. F. (2011) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e3182051a9b · Cited by 40
Frequent Use of Emergency Medical Services by the Elderly: A Case-Control Study Using Paramedic Records
Tangherlini, N. L., Pletcher, M. J., Covec, M., & Brown, J. F. (2010) · Prehospital and Disaster Medicine · doi:10.1017/s1049023x0000813x · Cited by 41
Psychological Resilience and Depressive Symptoms in Older Adults Diagnosed with Post-Polio Syndrome
Pierini, D., & Stuifbergen, A. M. (2010) · Rehabilitation Nursing · doi:10.1002/j.2048-7940.2010.tb00043.x · Cited by 41
Benzodiazepine use in the elderly: an indicator for inappropriately treated geriatric depression?
Assem‐Hilger, E., Jungwirth, S., Weissgram, S., Kirchmeyr, W., Fischer, P. A., & Barnas, C. (2008) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2155 · Cited by 43
Prevalence and Recognition of Depressive Symptoms Among Homebound Older Adults with Urinary Incontinence
Engberg, S. J., Sereika, S. M., Weber, E., Engberg, R. A., McDowell, B. J., & Reynolds, C. F. (2001) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/089198870101400306 · Cited by 41
Depressed mood in a cohort of elderly medical inpatients: Prevalence, clinical correlates and recognition rate
Pouget, R., Yersin, B., Wietlisbach, V., Burnand, B., & Büla, C. (2000) · Aging Clinical and Experimental Research · doi:10.1007/bf03339851 · Cited by 41
Mental Health/Medical Care Cost Offsets: Opportunities For Managed Care
Olfson, M., Sing, M., & Schlesinger, H. J. (1999) · Health Affairs · doi:10.1377/hlthaff.18.2.79 · Cited by 41
A Review of the Epidemiology of Major Depressive Disorder and of its consequences for Society and the individual.
McKeever, A., Agius, M. A., & Mohr, P. (2017) · PubMed · Cited by 41
Cost-effectiveness of a disease management program for major depression in elderly primary care patients
Bosmans, J. E., de Bruijne, M. C., van Hout, H. P. J., van Marwijk, H., Beekman, A. T. F., Bouter, L. M., Stalman, W. A. B., & van Tulder, M. W. (2006) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2006.00555.x · Cited by 40
Depression in the elderly: new concepts and therapeutic approaches
Mecocci, P., Cherubini, A., Mariani, E., Ruggiero, C., & Senin, U. (2004) · Aging Clinical and Experimental Research · doi:10.1007/bf03327382 · Cited by 41
The Relationship Between Frailty and Emotional Health in Older Patients with Advanced Cancer
Gilmore, N. J., Kehoe, L., Bauer, J., Xu, H., Hall, B., Wells, M., Lei, L., Culakova, E., Flannery, M. A., Grossman, V. A., et al. (2021) · The Oncologist · doi:10.1002/onco.13975 · Cited by 39
Psychiatric Emergency Services for the U.S. Elderly: 2008 and Beyond
Walsh, P., Currier, G. W., Shah, M. N., Lyness, J. M., & Friedman, B. (2008) · American Journal of Geriatric Psychiatry · doi:10.1097/jgp.0b013e31817e73c7 · Cited by 39
The feasibility and effectiveness of brief interventions to prevent depression in older subjects: a systematic review
Cole, M. G., & Dendukuri, N. (2004) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1200 · Cited by 39
The longitudinal relationship between the use of long-term care and depressive symptoms in older adults
Pot, A. M., Deeg, D. J. H., Twisk, J. W. R., Beekman, A. T. F., & Zarit, S. H. (2005) · The Gerontologist · doi:10.1093/geront/45.3.359 · Cited by 38
The Impact of Marital Conflict on Health and Health Care Utilization in Older Couples
Sandberg, J. G., Miller, R. B., Harper, J. M., Robila, M., & Davey, A. (2009) · Journal of Health Psychology · doi:10.1177/1359105308097938 · Cited by 38
Shards of sorrow: Older men's accounts of their depression experience
Apesoa‐Varano, E. C., Barker, J. C., & Hinton, L. (2014) · Social Science & Medicine · doi:10.1016/j.socscimed.2014.10.054 · Cited by 38
Healthcare costs associated with recognized and unrecognized depression in old age
Luppa, M., Heinrich, S., Angermeyer, M. C., König, H., & Riedel-Heller, S. G. (2008) · International Psychogeriatrics · doi:10.1017/s1041610208007680 · Cited by 38
Somatization among older primary care attenders
Sheehan, B., Bass, C., BRIGGS, R., & Jacoby, R. J. (2003) · Psychological Medicine · doi:10.1017/s003329170300789x · Cited by 38
Gulf War Illnesses: Causation and Treatment
Hodgson, M. J., & Kipen, H. M. (1999) · Journal of Occupational and Environmental Medicine · doi:10.1097/00043764-199906000-00010 · Cited by 38

Authors: Unützer, J.
Affiliations: University of Washington (US)
Corresponding author: Unützer, Jürgen
ORCID: Unützer, Jürgen
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 1997-05-28
Volume: 277
Issue: 20
Pages: 1618
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.1997.03540440052032
OpenAlex: W2153731374
Cited by: 697
References: 65
Citations by year: 2026: 4 · 2025: 4 · 2024: 3 · 2023: 2 · 2022: 9 · 2021: 11 · 2020: 17 · 2019: 14 · 2018: 15 · 2017: 8 · 2016: 17 · 2015: 22 · 2014: 12 · 2013: 37 · 2012: 29
FWCI: 61.67
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Keywords: depressive symptoms, geriatric depression, health care costs, health maintenance organizations, Medicare enrollees, primary care, chronic disease, mental health service utilization, older adults
MeSH terms: Aged, Chronic Disease, Depression, Family Practice, Female, Health Maintenance Organizations, Health Services, Humans, Male, Mental Health Services, Prospective Studies, Regression Analysis, United States, Prevalence, Health Care Costs

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Depressive Symptoms and the Cost of Health Services in HMO Patients Aged 65 Years and Older: A 4-Year Prospective Study

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks