The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Variation in Use of Blood Transfusion in Coronary Artery Bypass Graft Surgery
Abstract
CONTEXT: Perioperative blood transfusions are costly and have safety concerns. As a result, there have been multiple initiatives to reduce transfusion use. However, the degree to which perioperative transfusion rates vary among hospitals is unknown. OBJECTIVE: To assess hospital-level variation in use of allogeneic red blood cell (RBC), fresh-frozen plasma, and platelet transfusions in patients undergoing coronary artery bypass graft (CABG) surgery. DESIGN, SETTING, AND PATIENTS: An observational cohort of 102,470 patients undergoing primary isolated CABG surgery with cardiopulmonary bypass during calendar year 2008 at 798 sites in the United States, contributing data to the Society of Thoracic Surgeons Adult Cardiac Surgery Database. MAIN OUTCOME MEASURES: Perioperative (intraoperative and postoperative) transfusion of RBCs, fresh-frozen plasma, and platelets. RESULTS: At hospitals performing at least 100 on-pump CABG operations (82,446 cases at 408 sites), the rates of blood transfusion ranged from 7.8% to 92.8% for RBCs, 0% to 97.5% for fresh-frozen plasma, and 0.4% to 90.4% for platelets. Multivariable analysis including data from all 798 sites (102,470 cases) revealed that after adjustment for patient-level risk factors, hospital transfusion rates varied by geographic location (P = .007), academic status (P = .03), and hospital volume (P < .001). However, these 3 hospital characteristics combined only explained 11.1% of the variation in hospital risk-adjusted RBC usage. Case mix explained 20.1% of the variation between hospitals in RBC usage. CONCLUSION: Wide variability occurred in the rates of transfusion of RBCs and other blood products, independent of case mix, among patients undergoing CABG surgery with cardiopulmonary bypass in US hospitals in an adult cardiac surgical database.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Murphy, G. J., Reeves, B. C., Rogers, C. A., Rizvi, S. I. A., Culliford, L., & Angelini, G. D. (2007) · Circulation · doi:10.1161/circulationaha.107.698977 · Cited by 1,371 · cited 2×
“This does not necessarily contradict the large body of literature showing an association between transfusion and adverse outcome because those studies focused on patient-level risk.(2-9) Our analysis of mortality focused on comparing groups of hospitals according to their hospital-level transfusion rates.”
BackgroundResultDuration of Red-Cell Storage and Complications after Cardiac Surgery
Koch, C. G., Li, L., Sessler, D. I., Figueroa, P., Hoeltge, G. A., Mihaljevic, T., & Blackstone, E. H. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa070403 · Cited by 1,363
Shahian, D. M., O'Brien, S. M., Filardo, G., Ferraris, V. A., Haan, C. K., Rich, J. B., Normand, S.-L. T., DeLong, E. R., Shewan, C. M., Dokholyan, R. S., et al. (2009) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2009.05.053 · Cited by 1,256
Self-citationFerraris, V. A., Ferraris, S. P., Saha, S. P., Hessel, E. A., Haan, C. K., Royston, B. D., Bridges, C. R., Higgins, R. S. D., Despotis, G., Brown, J. R., et al. (2007) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2007.02.099 · Cited by 964
Self-citationKoch, C. G., Li, L., Duncan, A. I., Mihaljevic, T., Cosgrove, D. M., Loop, F. D., Starr, N. J., & Blackstone, E. H. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000217920.48559.d8 · Cited by 936
Funnel plots for comparing institutional performance
Spiegelhalter, D. J. (2005) · Statistics in Medicine · doi:10.1002/sim.1970 · Cited by 832
Activity‐based costs of blood transfusions in surgical patients at four hospitals
Shander, A., Hofmann, A., Ozawa, S., Theusinger, O. M., Gombotz, H., & Spahn, D. R. (2010) · Transfusion · doi:10.1111/j.1537-2995.2009.02518.x · Cited by 747
Effect of blood transfusion on long-term survival after cardiac operation
Engoren, M. C., Habib, R. H., Zacharias, A., Schwann, T. A., Riordan, C. J., & Durham, S. J. (2002) · The Annals of Thoracic Surgery · doi:10.1016/s0003-4975(02)03766-9 · Cited by 683
Transfusion in Coronary Artery Bypass Grafting is Associated with Reduced Long-Term Survival
Koch, C. G., Li, L., Duncan, A. I., Mihaljevic, T., Loop, F. D., Starr, N. J., & Blackstone, E. H. (2006) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2005.12.037 · Cited by 510
Stover, P. E., Siegel, L. C., Parks, R., Levin, J., Body, S. C., Maddi, R., D'Ambra, M. N., Mangano, D. T., & Spiess, B. D. (1998) · Anesthesiology · doi:10.1097/00000542-199802000-00009 · Cited by 423
Cited by
Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB*
Carson, J. L., Grossman, B. J., Kleinman, S., Tinmouth, A. T., Marques, M. B., Fung, M. K., Holcomb, J. B., Illoh, O., Kaplan, L. J., Katz, L. M., et al. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-157-1-201206190-00429 · Cited by 1,084
Increased Chest Tube Drainage Is Independently Associated With Adverse Outcome After Cardiac Surgery
Christensen, M. C., Dziewior, F., Kempel, A., & von Heymann, C. (2012) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2011.09.021 · Cited by 158
Metadata
- Authors
- Bennett-Guerrero, E., Zhao, Y., O'Brien, S. M., Ferguson, T. B., Peterson, E. D., Gammie, J. S., & Song, H. K.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2010-10-13
- Volume
- 304
- Issue
- 14
- Pages
- 1568
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2093059783
- Cited by
- 490
- References
- 23
- FWCI
- 21.74
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Variation in Use of Blood Transfusion in Coronary Artery Bypass Graft Surgery. https://app.cochat.ai/papers/10.1001/jama.2010.1406
- The paper
- Bennett-Guerrero, E., Zhao, Y., O'Brien, S. M., Ferguson, T. B., Peterson, E. D., Gammie, J. S., & Song, H. K. (2010). Variation in Use of Blood Transfusion in Coronary Artery Bypass Graft Surgery. JAMA. https://doi.org/10.1001/jama.2010.1406
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
