The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Activity‐based costs of blood transfusions in surgical patients at four hospitals
Open accessAbstract
BACKGROUND: Blood utilization has long been suspected to consume more health care resources than previously reported. Incomplete accounting for blood costs has the potential to misdirect programmatic decision making by health care systems. Determining the cost of supplying patients with blood transfusions requires an in‐depth examination of the complex array of activities surrounding the decision to transfuse. STUDY DESIGN AND METHODS: To accurately determine the cost of blood in a surgical population from a health system perspective, an activity‐based costing (ABC) model was constructed. Tasks and resource consumption (materials, labor, third‐party services, capital) related to blood administration were identified prospectively at two US and two European hospitals. Process frequency (i.e., usage) data were captured retrospectively from each hospital and used to populate the ABC model. RESULTS: All major process steps, staff, and consumables to provide red blood cell (RBC) transfusions to surgical patients, including usage frequencies, and direct and indirect overhead costs contributed to per‐RBC‐unit costs between $522 and $1183 (mean, $761 ± $294). These exceed previously reported estimates and were 3.2‐ to 4.8‐fold higher than blood product acquisition costs. Annual expenditures on blood and transfusion‐related activities, limited to surgical patients, ranged from $1.62 to $6.03 million per hospital and were largely related to the transfusion rate. CONCLUSION: Applicable to various hospital practices, the ABC model confirms that blood costs have been underestimated and that they are geographically variable and identifies opportunities for cost containment. Studies to determine whether more stringent control of blood utilization improves health care utilization and quality, and further reduces costs, are warranted.
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The environment and disease: association or causation?
Hill, A. B. (2015) · Journal of the Royal Society of Medicine · doi:10.1177/0141076814562718 · Cited by 7,285
The Environment and Disease: Association or Causation?
Hill, A. B. (1965) · Proceedings of the Royal Society of Medicine · doi:10.1177/003591576505800503 · Cited by 6,974
The Risk of Transfusion-Transmitted Viral Infections
Schreiber, G. B., Busch, M. P., Kleinman, S. H., & Korelitz, J. J. (1996) · New England Journal of Medicine · doi:10.1056/nejm199606273342601 · Cited by 1,867
Transfusion Medicine — Blood Transfusion
Goodnough, L. T., Brecher, M. E., Kanter, M. H., & AuBuchon, J. P. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400606 · Cited by 880
Reports of 355 transfusion‐associated deaths: 1976 through 1985
Sazama, K. (1990) · Transfusion · doi:10.1046/j.1537-2995.1990.30790385515.x · Cited by 729
Relationship between TISS and ICU cost
Dickie, H., Vedio, A., Dundas, R., Treacher, D., & Leach, R. M. (1998) · Intensive Care Medicine · doi:10.1007/s001340050709 · Cited by 559
The Cost Effectiveness of Preoperative Autologous Blood Donations
Etchason, J., Petz, L., Keeler, E., Calhoun, L., Kleinman, S., Snider, C., Fink, A., & Brook, R. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503163321106 · Cited by 495
Transfusion-Related Acute Lung Injury: Report of a Clinical Look-Back Investigation
Kopko, P. M., Marshall, C. S., MacKenzie, M. R., Holland, P. V., & Popovsky, M. A. (2002) · JAMA · doi:10.1001/jama.287.15.1968 · Cited by 422
Serious hazards of transfusion (SHOT) initiative: analysis of the first two annual reports
Williamson, L. M., Lowe, S., Love, E. M., Cohen, H., Soldan, K., McClelland, D. B. L., Skacel, P., & Barbara, J. A. J. (1999) · BMJ · doi:10.1136/bmj.319.7201.16 · Cited by 335
Carson, J. L., Altman, D. G., Duff, A., Noveck, H., Weinstein, M. P., Sonnenberg, F. A., Hudson, J. I., & Provenzano, G. (1999) · Transfusion · doi:10.1046/j.1537-2995.1999.39070694.x · Cited by 329
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Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion
Carson, J. L., Stanworth, S. J., Roubinian, N., Fergusson, D. A., Triulzi, D., Doree, C., & Hebert, P. C. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002042.pub4 · Cited by 1,250
Variation in Use of Blood Transfusion in Coronary Artery Bypass Graft Surgery
Bennett-Guerrero, E., Zhao, Y., O'Brien, S. M., Ferguson, T. B., Peterson, E. D., Gammie, J. S., & Song, H. K. (2010) · JAMA · doi:10.1001/jama.2010.1406 · Cited by 490
Transfusion thresholds for guiding red blood cell transfusion
Carson, J. L., Stanworth, S. J., Dennis, J. A., Trivella, M., Roubinian, N., Fergusson, D. A., Triulzi, D., Dorée, C., & Hébert, P. C. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002042.pub5 · Cited by 322
Metadata
- Authors
- Shander, A., Hofmann, A., Ozawa, S., Theusinger, O. M., Gombotz, H., & Spahn, D. R.
- Venue
- Transfusion
- Publisher
- Wiley
- Published
- 2010-03-25
- Volume
- 50
- Issue
- 4
- Pages
- 753-765
- ISSN
- 0041-1132 (ISSN-L)
- 1537-2995
- OpenAlex
- W2158392152
- Cited by
- 747
- References
- 23
- FWCI
- 16.45
- Type
- journal article
- Language
- en
- Open access
- green
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