The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
SARS-CoV-2–Specific Antibodies in Breast Milk After COVID-19 Vaccination of Breastfeeding Women
Open accessAbstract
This study found robust secretion of SARS-CoV-2 specific IgA and IgG antibodies in breast milk for 6 weeks after vaccination.IgA secretion was evident as early as 2 weeks after vaccination followed by a spike in IgG after 4 weeks (a week after the second vaccine).A few other studies have shown similar findings in women infected with COVID-19.5 Antibodies found in breast milk of these women showed strong neutralizing effects, suggesting a potential protective effect against infection in the infant.The study has limitations.First, no functional assays were performed.However, previous studies have showed neutralizing capacities of the same antibodies as measured for this study.Second, serum antibody testing or SARS-CoV-2 real-time reverse-transcriptase polymerase chain reaction testing were not performed, which would have provided interesting correlates.
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“Importantly, functional neutralizing antibodies against SARS-CoV-2 were found in infant cord blood and in the breast milk of vaccinated pregnant women”
From COVID-19 mRNA vaccines: Platforms and current developments (2022) · cites this paper as [118]
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“suggesting that there is a protective effect for newborns.116, 117, 118”
From COVID-19 mRNA vaccines: Platforms and current developments (2022) · cites this paper as [118]
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Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack, F. P., Thomas, S. J., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Perez, J. L., Pérez Marc, G., Moreira, E. D., Zerbini, C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2034577 · Cited by 14,592
Pace, R. M., Williams, J. E., Järvinen, K. M., Belfort, M. B., Pace, C. D. W., Lackey, K. A., Gogel, A. C., Nguyen-Contant, P., Kanagaiah, P., Fitzgerald, T., et al. (2021) · mBio · doi:10.1128/mbio.03192-20 · Cited by 315
Ozberk, V., Reynolds, S. L., Huo, Y., Calcutt, A., Eskandari, S., Dooley, J., Mills, J.-L. S., Rasmussen, I. S., Dietrich, J., Pandey, M., et al. (2021) · mBio · doi:10.1128/mbio.03537-20 · Cited by 32
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Filip, R., Gheorghita Puscaselu, R., Anchidin-Norocel, L., Dimian, M., & Savage, W. K. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12081295 · Cited by 802
Breastfeeding: crucially important, but increasingly challenged in a market-driven world
Pérez‐Escamilla, R., Tomori, C., Hernández‐Cordero, S., Baker, P., Barros, A. J. D., Bégin, F., Chapman, D. J., Grummer‐Strawn, L. M., McCoy, D., Menon, P., et al. (2023) · The Lancet · doi:10.1016/s0140-6736(22)01932-8 · Cited by 632
Effectiveness of the BNT162b2 mRNA COVID-19 vaccine in pregnancy
Dagan, N., Barda, N., Biron-Shental, T., Makov-Assif, M., Key, C., Kohane, I. S., Hernán, M. A., Lipsitch, M., Hernandez-Diaz, S., Reis, B. Y., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01490-8 · Cited by 312
COVID-19 mRNA vaccines: Platforms and current developments
Szabó, G. T., Mahiny, A. J., & Vlatkovic, I. (2022) · Molecular Therapy · doi:10.1016/j.ymthe.2022.02.016 · Cited by 308
Gurol‐Urganci, I., Jardine, J. E., Carroll, F. E., Draycott, T. J., Dunn, G., Frémeaux, A. E., Harris, T., Hawdon, J. M., Morris, E., Muller, P., et al. (2021) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2021.05.016 · Cited by 296
Metadata
- Authors
- Perl, S. H., Uzan-Yulzari, A., Klainer, H., Asiskovich, L., Youngster, M., Rinott, E., & Youngster, I.
- Affiliations
- Assaf Harofeh Medical Center (IL)
- Ben-Gurion University of the Negev (IL)
- Tel Aviv University (IL)
- Corresponding author
- Youngster, Ilan
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2021-05-18
- Volume
- 325
- Issue
- 19
- Pages
- 2013
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC8042567
- OpenAlex
- W3155604755
- Cited by
- 285
- References
- 3
- Citations by year
- 2026: 10 · 2025: 12 · 2024: 19 · 2023: 57 · 2022: 102 · 2021: 85
- FWCI
- 20.82
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Obstetrics and Gynecology › COVID-19 Impact on Reproduction
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Keywords
- SARS-CoV-2, COVID-19 vaccination, breastfeeding, breast milk, IgA, IgG, maternal antibodies, infant protection, neutralizing antibodies, vaccine response
- MeSH terms
- COVID-19, COVID-19 Vaccines, Adult, Antibodies, Viral, Breast Feeding, Female, Humans, Immunoglobulin A, Immunoglobulin G, Milk, Human, Prospective Studies
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