Sublingual buprenorphine-naloxone exposure and dental disease—Reply
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Clear evidence that TMB causes oral health problems has remained unavailable without more rigorous study designs such as randomized controlled trials.
“Clear evidence for a causal effect of TMB has remained elusive to date in the absence of more rigorous study designs including randomized controlled trials.”
From Oral Health Risks of Transmucosal Buprenorphine: Commentary on Tuan et al. and Zheng et al. (2025) · cites this paper as [9]
Etminan and colleagues' sampling strategy and conclusions drew criticism and concern that misinterpreted results could affect practice.
“The study’s sampling strategy and conclusions drew criticism and concern about the potential impact of misinterpreted results on practice.9”
From Oral Health Risks of Transmucosal Buprenorphine: Commentary on Tuan et al. and Zheng et al. (2025) · cites this paper as [9]
Cites
Hansen, H., Siegel, C., Case, B. G., Bertollo, D. N., DiRocco, D., & Galanter, M. S. (2013) · The Journal of Behavioral Health Services & Research · doi:10.1007/s11414-013-9341-3 · Cited by 224 · see citing works
Greenland, S. (2020) · International Journal of Epidemiology · doi:10.1093/ije/dyaa095 · Cited by 27 · see citing works
Association between sublingual buprenorphine-naloxone exposure and dental disease
Etminan, M., Rezaeianzadeh, R., Kezouh, A., & Aminzadeh, K. (2022) · JAMA · doi:10.1001/jama.2022.17485 · Cited by 25 · see citing works
Self-citationSublingual Buprenorphine and Dental Problems
Suzuki, J., Mittal, L. P., & Woo, S. (2013) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.13l01533 · Cited by 10 · see citing works
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Oral Health Risks of Transmucosal Buprenorphine: Commentary on Tuan et al. and Zheng et al.
Black, A. C., & Becker, W. C. (2025) · Journal of Addiction Medicine · doi:10.1097/adm.0000000000001452 · Cited by 1 · see citing works
- Authors
- Etminan, M., & Rezaeianzadeh, R.
- Affiliations
- University of British Columbia (CA)
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2023-04-11
- Volume
- 329
- Issue
- 14
- Pages
- 1224
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W4364353493
- Cited by
- 1
- References
- 4
- Citations by year
- 2025: 1
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
- Keywords
- dental diseases, opioid analgesics, oral health, drug exposure
- MeSH terms
- Buprenorphine, Naloxone Drug Combination, Administration, Sublingual, Humans, Stomatognathic Diseases, Narcotic Antagonists
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