Cited by 973HIV/AIDS Research and InterventionsAdolescent Sexual and Reproductive HealthHIV, Drug Use, Sexual Risk

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Efficacy of Risk-Reduction Counseling to Prevent Human Immunodeficiency Virus and Sexually Transmitted Diseases: A Randomized Controlled Trial

Kamb, Mary L., Fishbein, Martin, Douglas, Jr, John M., Rhodes, Fen, Rogers, Judy, Bolan, Gail, Zenilman, Jonathan, Hoxworth, Tamara, Malotte, C. Kevin, Iatesta, Michael, Kent, Charlotte, Lentz, Andrew, Graziano, Sandra, Byers, Robert H., Peterman, Thomas A., for the Project RESPECT Study Group·1998·JAMA

DOI 10.1001/jama.280.13.1161

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Abstract

CONTEXT: The efficacy of counseling to prevent infection with the human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) has not been definitively shown. OBJECTIVE: To compare the effects of 2 interactive HIV/STD counseling interventions with didactic prevention messages typical of current practice. DESIGN: Multicenter randomized controlled trial (Project RESPECT), with participants assigned to 1 of 3 individual face-to-face interventions. SETTING: Five public STD clinics (Baltimore, Md; Denver, Colo; Long Beach, Calif; Newark, NJ; and San Francisco, Calif) between July 1993 and September 1996. PARTICIPANTS: A total of 5758 heterosexual, HIV-negative patients aged 14 years or older who came for STD examinations. INTERVENTIONS: Arm 1 received enhanced counseling, 4 interactive theory-based sessions. Arm 2 received brief counseling, 2 interactive risk-reduction sessions. Arms 3 and 4 each received 2 brief didactic messages typical of current care. Arms 1, 2, and 3 were actively followed up after enrollment with questionnaires at 3, 6, 9, and 12 months and STD tests at 6 and 12 months. An intent-to-treat analysis was used to compare interventions. MAIN OUTCOME MEASURES: Self-reported condom use and new diagnoses of STDs (gonorrhea, chlamydia, syphilis, HIV) defined by laboratory tests. RESULTS: At the 3- and 6-month follow-up visits, self-reported 100% condom use was higher (P<.05) in both the enhanced counseling and brief counseling arms compared with participants in the didactic messages arm. Through the 6-month interval, 30% fewer participants had new STDs in both the enhanced counseling (7.2%; P= .002) and brief counseling (7.3%; P= .005) arms compared with those in the didactic messages arm (10.4%). Through the 12-month study, 20% fewer participants in each counseling intervention had new STDs compared with those in the didactic messages arm (P = .008). Consistently at each of the 5 study sites, STD incidence was lower in the counseling intervention arms than in the didactic messages intervention arm. Reduction of STD was similar for men and women and greater for adolescents and persons with an STD diagnosed at enrollment. CONCLUSIONS: Short counseling interventions using personalized risk reduction plans can increase condom use and prevent new STDs. Effective counseling can be conducted even in busy public clinics.

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Hilton, C., Sabundayo, B. P., Langan, S. J., Hilton, M., Henson, C., Quinn, T. C., Margolick, J. B., & Nelson, K. E. (2002) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-200212010-00008 · Cited by 9
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Kiene, S. M., Stein, M. D., Bateganya, M. H., Wanyenze, R. K., Mayer, K. H., & Lule, H. (2009) · SAHARA-J Journal of Social Aspects of HIV/AIDS · doi:10.1080/17290376.2009.9724939 · Cited by 9
“Providing HIV prevention information during HIV testing has been shown to be less effective than client-centered counselling in reducing HIV risk behaviour and STI incidence in the US (Kamb et al., 1998).”
Background
Are we going to close social gaps in HIV? Likely effects of behavioral HIV-prevention interventions on health disparities
Albarracín, D., & Durantini, M. R. (2010) · Psychology Health & Medicine · doi:10.1080/13548506.2010.498892 · Cited by 9
“Thus, we assumed r ¼ 0 and r ¼ 0.99 as the most extreme values, and also imputed correlations from Project RESPECT (see Kamb et al., 1998), which provided moderate values of this association.”
MethodInfluential
Factors affecting accessibility and acceptability of voluntary counselling and testing among high risk group (HRG) for human immunodeficiency virus (HIV) in NWFP Pakistan.
Afridi, N. K., Khan, S. A., & Fatima, S. (2010) · PubMed · Cited by 9
Testing the efficacy of a brief sexual risk reduction intervention among high-risk American Indian adults: study protocol for a randomized controlled trial
Chambers, R. A., Tingey, L., Beach, A. B., Barlow, A., & Rompalo, A. (2016) · BMC Public Health · doi:10.1186/s12889-016-3040-y · Cited by 9
“The effect size is based on observed impacts in past trials of the original EBI (Project RESPECT) [33, 40].”
BackgroundMethodInfluential
The Ethics of Public Health Practice for the Prevention and Control of STDs
Semaan, S., & Leinhos, M. R. (2007) · Springer eBooks · doi:10.1007/978-0-387-48740-3_23 · Cited by 9
Quality of life improvement in Latinas receiving combined substance use disorders and trauma-specific treatment: a cohort evaluation report
Cruz, M. A., Miranda, C., Fernández-Santos, D. M., Orobitg-Brenes, D., Hunter-Mellado, R. F., & Carrion, I. S. (2017) · Health and Quality of Life Outcomes · doi:10.1186/s12955-017-0667-z · Cited by 9
“under the Project RESPECT study) [45, 46] evidence-based practices (EBPs).”
Background
Sex-negotiation strategies and safer-sex practices among married women in South-western Nigeria
Popoola, B. I. (2009) · Sexual & Relationship Therapy · doi:10.1080/14681990903114352 · Cited by 9
Correlates of Adolescent Females' Worry About Undesired Pregnancy
Crosby, R. A., DiClemente, R. J., Wingood, G. M., Sionéan, C., Cobb, B. K., Harrington, K., Davies, S., Hook, E. W., & Oh, M. K. (2001) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/s1083-3188(01)00089-4 · Cited by 9
Identifying the Links between Violence against Women and HIV/AIDS: Ecosocial and Human Rights Frameworks Offer Insight into US Prevention Policies
Teti, M., Chilton, M. M., Lloyd, L., & Rubinstein, S. (2006) · Health and Human Rights · doi:10.2307/4065401 · Cited by 9
High-Risk Women's Willingness to Try a Simulated Vaginal Microbicide: Results from a Pilot Study
Mosack, K. E., Weeks, M. R., Sylla, L. N., & Abbott, M. (2006) · Women & Health · doi:10.1300/j013v42n02_05 · Cited by 9
“Microbicides, HIV prevention, sexual assertiveness, acceptability Despite an increase in HIV prevention efforts (Belcher et al., 1998; Kamb et al., 1998; Stanton et al., 2000), including condom promotion interventions (Collins, Kohler, DiClemente, & Wang, 1999; Kalichman, Cherry, & Browne-Sperling,…”
Background
Working with Families Affected by HIV/AIDS
Yarhouse, M. A. (2003) · American Journal of Family Therapy · doi:10.1080/01926180301124 · Cited by 9
HIV Prevention: Behavioral Interventions in Correctional Settings
Zack, B. (2007) · Springer eBooks · doi:10.1007/978-0-387-71695-4_10 · Cited by 9
Editorial Response: It’s All in the Measurement: Consistent Condom Use Is Effective in Preventing Sexually Transmitted Infections
Celentano, D. D. (2004) · Sexually Transmitted Diseases · doi:10.1097/01.olq.0000117589.12564.1b · Cited by 9
Fiscal loss and program fidelity: impact of the economic downturn on HIV/STI prevention program fidelity
Catania, J. A., Dolcini, M. M., Gandelman, A. A., Narayanan, V., & McKay, V. R. (2014) · Translational Behavioral Medicine · doi:10.1007/s13142-013-0242-z · Cited by 8
Efficacy of partner notification for Chlamydia trachomatis among young adults in youth health centres in Uppsala County, Sweden
Sylvan, S., & Hedlund, J. (2009) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2008.03080.x · Cited by 8
Participants' perspectives on improving retention in HIV care after hospitalization: A post-study qualitative investigation of the MAPPS study
Minick, S. G., May, S., Amico, K. R., Cully, J. A., Davila, J. A., Kallen, M. A., & Giordano, T. P. (2018) · PLoS ONE · doi:10.1371/journal.pone.0202917 · Cited by 8
The First 40 Years of AIDS: Promising Programs, Limited Success
Darrow, W. W. (2021) · AIDS and Behavior · doi:10.1007/s10461-021-03497-1 · Cited by 8
Enhancing Acceptability and Use of Sexual Barrier Products Among HIV Concordant and Discordant Couples
Jones, D. L., Kashy, D. A., Villar-Loubet, O. M., & Weiss, S. M. (2013) · AIDS and Behavior · doi:10.1007/s10461-013-0449-5 · Cited by 8
From questionnaire to conversation: A structural intervention to improve HIV test counseling
Sheon, N. M., Lee, S. H., & Facente, S. N. (2010) · Patient Education and Counseling · doi:10.1016/j.pec.2010.08.011 · Cited by 8
Sexually Transmitted Disease Testing Protocols, Sexually Transmitted Disease Testing, and Discussion of Sexual Behaviors in HIV Clinics in Los Angeles County
Taylor, M. M., McClain, T., Javanbakht, M., Brown, B., Aynalem, G., Smith, L. V., Kerndt, P. R., & Peterman, T. A. (2005) · Sexually Transmitted Diseases · doi:10.1097/01.olq.0000154500.01801.db · Cited by 8
Payoff from AIDS behavioral prevention research
Pequegnat, W., & Stover, E. S. (2009) · Elsevier eBooks · doi:10.1016/b978-0-12-374235-3.00007-8 · Cited by 9
Daily diary study of adult men’s and women’s event-level sexual motivations and sexual behaviour
Hensel, D. J., He, F., Harezlak, J., & Fortenberry, J. D. (2016) · Sexual Health · doi:10.1071/sh16109 · Cited by 8
Contraceptive practices of non-HIV-seropositive injecting drug users
Vidal-Trecan, G. M., Warszawski, J., Coste, J., Bajos, N., Delamare, N., Grenier‐Sennelier, C., & Boissonnas, A. (2003) · European Journal of Epidemiology · doi:10.1023/a:1025643421939 · Cited by 8
Early Detection of HIV: Assessing the Legislative Context
Morin, S. F. (2000) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00042560-200012152-00009 · Cited by 8
Sexual and Reproductive Behavior of Women With HIV Infection
Wilson, T. E. (2001) · Clinical Obstetrics & Gynecology · doi:10.1097/00003081-200106000-00014 · Cited by 8
“Several of these programs have been demonstrated to produce desired outcomes such as decreased numbers of sexual partners, increased condom use compliance, and reduced rates of sexually transmitted disease (STD) incidence.(1,2) The benefits derived from these programs are limited, however, in their almost complete exc…”
Background
Development of an HIV risk reduction counselling intervention for use in South African sexually transmitted infection clinics
Mathiti, V., Simbayi, L. C., Jooste, S., Kekana, Q., Nibe, X. P., Shasha, L., Bidla, P., Magubane, P., Cain, D. N., Cherry, C., et al. (2005) · SAHARA-J Journal of Social Aspects of HIV/AIDS · doi:10.1080/17290376.2005.9724850 · Cited by 8
Abstinence and Safer Sex Among Adolescents
Berman, S. M. (1999) · JAMA · doi:10.1001/jama.281.16.1485 · Cited by 8
British HIV Association guidelines
Hay, P., & Mitchla, Z. (1998) · The Lancet · doi:10.1016/s0140-6736(05)60568-5 · Cited by 8
When risk is low: primary care physicians’ counseling about HIV prevention
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A Prospective Event-Level Analysis of Condom Use Experiences Following STI Testing Among Patients in Three US Cities
Crosby, R. A., Shrier, L. A., Charnigo, R. J., Weathers, C., Sanders, S. A., Graham, C. A., Milhausen, R. R., & Yarber, W. L. (2012) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e318265a951 · Cited by 7
Reflexões sobre o aconselhamento em HIV/AIDS em uma perspectiva freireana
Miranda, K. C. L., Barroso, M. G. T., da Silva, L. M. S., & da Silva, M. R. F. (2008) · Redalyc (Universidad Autónoma del Estado de México) · Cited by 7
Do ask, do tell
Mayer, K. H. (2014) · AIDS · doi:10.1097/qad.0000000000000274 · Cited by 7
Association of Delayed Treatment of Chlamydial Infection and Gonorrhea in Pregnancy and Preterm Birth
Burdette, E. R., Young, M. R., Dude, C. M., Wall, K. M., & Haddad, L. B. (2021) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000001490 · Cited by 7

Authors: Kamb, M. L., Fishbein, M., Douglas, Jr., Rhodes, F., Rogers, J., Bolan, G., Zenilman, J., Hoxworth, T., Malotte, C. K., Iatesta, M., Kent, C., Lentz, A., Graziano, S., Byers, R. H., Peterman, T. A., & for the Project RESPECT Study Group
Affiliations: Centers for Disease Control and Prevention (US)
ORCID: Kamb, Mary L.
Bolan, Gail
Hoxworth, Tamara
Venue: JAMA
Publisher: American Medical Association (AMA)
Published: 1998-10-07
Volume: 280
Issue: 13
Pages: 1161
ISSN: 0002-9955 (ISSN-L)
0098-7484
DOI: 10.1001/jama.280.13.1161
OpenAlex: W2153335467
Cited by: 973
References: 22
Citations by year: 2026: 5 · 2025: 3 · 2024: 5 · 2023: 6 · 2022: 14 · 2021: 11 · 2020: 11 · 2019: 17 · 2018: 21 · 2017: 18 · 2016: 32 · 2015: 26 · 2014: 57 · 2013: 35 · 2012: 49
FWCI: 29.60
Type: journal article
Language: en
Open access: closed
Locations: JAMA (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Adolescent Sexual and Reproductive Health
Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
Keywords: HIV prevention, sexually transmitted infections, risk reduction counseling, condom use, STD incidence, gonorrhea, chlamydia, syphilis, HIV, STD clinics, adolescents, HIV-negative patients, sexual behavior change
MeSH terms: Adolescent, Adult, Community Health Services, Counseling, Female, Humans, Male, Risk Factors, Sexually Transmitted Diseases, United States, HIV Infections

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Efficacy of Risk-Reduction Counseling to Prevent Human Immunodeficiency Virus and Sexually Transmitted Diseases: A Randomized Controlled Trial

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