The DOI matches its Crossref record; 68 of the 70 references it cites were found in a registry or an index.
Cost of Lost Productive Work Time Among US Workers With Depression
Abstract
CONTEXT: Evidence consistently indicates that depression has adversely affected work productivity. Estimates of the cost impact in lost labor time in the US workforce, however, are scarce and dated. OBJECTIVE: To estimate the impact of depression on labor costs (ie, work absence and reduced performance while at work) in the US workforce. DESIGN, SETTING, AND PARTICIPANTS: All employed individuals who participated in the American Productivity Audit (conducted August 1, 2001-July 31, 2002) between May 20 and July 11, 2002, were eligible for the Depressive Disorders Study. Those who responded affirmatively to 2 depression-screening questions (n = 692), as well as a 1:4 stratified random sample of those responding in the negative (n = 435), were recruited for and completed a supplemental interview using the Primary Care Evaluation of Mental Disorders Mood Module for depression, the Somatic Symptom Inventory, and a medical and treatment history for depression. Excess lost productive time (LPT) costs from depression were derived as the difference in LPT among individuals with depression minus the expected LPT in the absence of depression projected to the US workforce. MAIN OUTCOME MEASURE: Estimated LPT and associated labor costs (work absence and reduced performance while at work) due to depression. RESULTS: Workers with depression reported significantly more total health-related LPT than those without depression (mean, 5.6 h/wk vs an expected 1.5 h/wk, respectively). Eighty-one percent of the LPT costs are explained by reduced performance while at work. Major depression accounts for 48% of the LPT among those with depression, again with a majority of the cost explained by reduced performance while at work. Self-reported use of antidepressants in the previous 12 months among those with depression was low (<33%) and the mean reported treatment effectiveness was only moderate. Extrapolation of these survey results and self-reported annual incomes to the population of US workers suggests that US workers with depression employed in the previous week cost employers an estimated 44 billion dollars per year in LPT, an excess of 31 billion dollars per year compared with peers without depression. This estimate does not include labor costs associated with short- and long-term disability. CONCLUSIONS: A majority of the LPT costs that employers face from employee depression is invisible and explained by reduced performance while at work. Use of treatments for depression appears to be relatively low. The combined LPT burden among those with depression and the low level of treatment suggests that there may be cost-effective opportunities for improving depression-related outcomes in the US workforce.
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“Among people with specific social and productive roles, MDD is found to predict significant decrements in role functioning (e.g., low marital quality, low work performance, low earnings).”
From The Costs of Depression (2012) · cites this paper as [65]
In the citing paper
“All these studies found that MDE and MDD significantly predict overall lost work performance. Several studies attempted to estimate the annual salary-equivalent human capital value of these losses. These estimates were in the range $30.1 billion66 to $51.5 billion.64”
From The Costs of Depression (2012) · cites this paper as [65]
In the citing paper
“Suicide is ranked as the second leading cause of death among 15-29 year olds and as the 15thmost common cause of death at all ages worldwide. 201”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [201]
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Metadata
- Authors
- Stewart, W. F.
- Corresponding author
- Stewart, Walter F.
- ORCID
- Stewart, Walter F.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2003-06-18
- Volume
- 289
- Issue
- 23
- Pages
- 3135
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2105346851
- Cited by
- 1,421
- References
- 70
- Citations by year
- 2026: 22 · 2025: 20 · 2024: 37 · 2023: 55 · 2022: 48 · 2021: 85 · 2020: 61 · 2019: 48 · 2018: 71 · 2017: 61 · 2016: 113 · 2015: 71 · 2014: 78 · 2013: 81 · 2012: 61
- FWCI
- 109.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eli Lilly and Company
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Keywords
- depression, labor productivity, labor costs, absenteeism, employer costs, antidepressant use, treatment effectiveness, economic burden of depression, somatic symptoms, disability costs, mental health workforce planning, health care financing, health care delivery, health care utilization, health care costs
- MeSH terms
- Adult, Depression, Depressive Disorder, Efficiency, Employment, Factor Analysis, Statistical, Female, Humans, Male, Middle Aged, Population Surveillance, United States, Linear Models, Cost of Illness, Diagnostic and Statistical Manual of Mental Disorders
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