Indicated prevention interventions in the workplace for depressive symptoms: a systematic review and meta-analysis
Abstract
Context Depressive symptoms are highly prevalent and cause substantive morbidities and loss of functioning among employees. Depression may be prevented at its early stages. However, there is a paucity of information regarding indicated preventive interventions for depression among employees. The objective of this review is to examine the effectiveness of indicated interventions for the reduction of depressive symptoms in the workplace.Evidence acquisition A systematic review and meta-analysis of articles published between January 2000 and September 2017 was conducted using major electronic databases, including PubMed/MEDLINE, PsycINFO, EMBASE, SOCINDEX, and ABI/ProQuest. Studies were selected based on a set of predefined inclusion criteria. Primary outcome measures were depressive symptomatology, and the interventions were preventive in nature. Studies were pooled based on the intervention type and the effect size was measured using the standardized mean difference.Evidence synthesis A computer and hand search of the literature yielded 4,462 papers, from which 16 trials were identified to be suitable for meta-analysis. Eight of 16 studies reported significant effects for workplace preventive interventions targeting depressive symptoms in which six were cognitive behavioral therapy (CBT)-based interventions and two were non-CBT-based interventions. Small to medium effect sizes were found for both CBT- and non-CBT-based interventions (standardized mean difference= -0.44, 95% CI= -0.61, -0.26, I 2=62.1% and standardized mean difference= -0.32, 95% CI= -0.59, -0.06, I 2=58%, respectively).Conclusions This review demonstrates that indicated interventions can significantly reduce the level of depressive symptoms among workers. The implementation of evidence-based workplace interventions should consequently be considered to prevent the development of depressive symptoms among employees.
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The evidence base on exercise and social interventions to prevent antenatal depression in mothers remains insufficient to support implementation.
“It concludes, consistent with an earlier systematic review on exercise, 416 that while the evidence base on exercise and social interventions to prevent antenatal depression in mothers is growing, it remains insufficient to support implementation and points to a prominent area of research need.”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [416]
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- Authors
- Nigatu, Y. T., Huang, J., Rao, S., Gillis, K., Merali, Z., & Wang, J.
- Affiliations
- University of Ottawa (CA)
- Corresponding author
- Wang, JianLi
- Venue
- American Journal of Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 56
- Issue
- 1
- Pages
- e23-e33
- ISSN
- 0749-3797 (ISSN-L)
- OpenAlex
- W2904910853
- Cited by
- 41
- References
- 45
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 5 · 2023: 15 · 2022: 7 · 2021: 7 · 2020: 2 · 2019: 2
- FWCI
- 0.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- eCommons - AKU (Aga Khan University) (submittedVersion)
- Funders
- Canadian Institutes of Health Research and Movember Foundation
- Topics
- Health Sciences › Health Professions › General Health Professions › Workplace Health and Well-being
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- depressive symptoms, depression prevention, workplace interventions, indicated prevention, cognitive behavioral therapy, workers, workplace mental health, early intervention
- MeSH terms
- Depression, Humans, Cognitive Behavioral Therapy, Occupational Health, Workplace, Evidence-Based Medicine
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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