The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Effect of Exercise on Total and Intra-abdominal Body Fat in Postmenopausal Women: A Randomized Controlled Trial
Open accessAbstract
CONTEXT: The increasing prevalence of obesity is a major public health concern. Physical activity may promote weight and body fat loss. OBJECTIVE: To examine the effects of exercise on total and intra-abdominal body fat overall and by level of exercise. DESIGN: Randomized controlled trial conducted from 1997 to 2001. SETTING AND PARTICIPANTS: A total of 173 sedentary, overweight (body mass index > or =24.0 and >33% body fat), postmenopausal women aged 50 to 75 years who were living in the Seattle, Wash, area. INTERVENTION: Participants were randomly assigned to an intervention consisting of exercise facility and home-based moderate-intensity exercise (n = 87) or a stretching control group (n = 86). MAIN OUTCOME MEASURE: Changes in body weight and waist and hip circumferences at 3 and 12 months; total body, intra-abdominal, and subcutaneous abdominal fat at 12 months. RESULTS: Twelve-month data were available for 168 women. Women in the exercise group participated in moderate-intensity sports/recreational activity for a mean (SD) of 3.5 (1.2) d/wk for 176 (91) min/wk. Walking was the most frequently reported activity. Exercisers showed statistically significant differences from controls in baseline to 12-month changes in body weight (-1.4 kg; 95% confidence interval [CI], -2.5 to -0.3 kg), total body fat (-1.0%; 95% CI, -1.6% to -0.4%), intra-abdominal fat (-8.6 g/cm2; 95% CI, -17.8 to 0.9 g/cm2), and subcutaneous abdominal fat (-28.8 g/cm2); 95% CI, -47.5 to -10.0 g/cm2). A significant dose response for greater body fat loss was observed with increasing duration of exercise. CONCLUSIONS: Regular exercise such as brisk walking results in reduced body weight and body fat among overweight and obese postmenopausal women.
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“Likewise, a greater percentage loss in VAT percentage than in body weight occurred after 12 months in a moderate-intensity exercise intervention study of sedentary, overweight, postmenopausal women. VAT loss was exercise dose-dependent (253).”
From Lack of Exercise Is a Major Cause of Chronic Diseases (2012) · cites this paper as [253]
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Self-citationLongitudinal Data Analysis for Discrete and Continuous Outcomes
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Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases
Pedersen, B. K., & Saltin, B. (2015) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/sms.12581 · Cited by 3,514
“There is a link between regular physical activity, with or without weight loss, and reduction in visceral fat volume (Ross & Janssen, 2001; Irwin et al., 2003; Giannopoulou et al., 2005; Janiszewski & Ross, 2007).”
BackgroundLack of Exercise Is a Major Cause of Chronic Diseases
Booth, F. W., Roberts, C. K., & Laye, M. J. (2012) · Comprehensive Physiology · doi:10.1002/cphy.c110025 · Cited by 2,575
Garvey, W. T., Mechanick, J. I., Brett, E. M., Garber, A. J., Hurley, D. L., Jastreboff, A. M., Nadolsky, K., Pessah-Pollack, R., & Plodkowski, R. (2016) · Endocrine Practice · doi:10.4158/ep161365.gl · Cited by 1,914
Franz, M. J., VanWormer, J. J., Crain, A. L., Boucher, J. L., Histon, T., Caplan, W., Bowman, J. D., & Pronk, N. P. (2007) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2007.07.017 · Cited by 1,559
Doyle, C., Kushi, L. H., Byers, T., Courneya, K. S., Demark-Wahnefried, W., Grant, B., McTiernan, A., Rock, C. L., Thompson, C., Gansler, T., et al. (2006) · CA: A Cancer Journal for Clinicians · doi:10.3322/canjclin.56.6.323 · Cited by 950
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Metadata
- Authors
- Irwin, M. L., Yasui, Y., Ulrich, C. M., Bowen, D., Rudolph, R. E., Schwartz, R. S., Yukawa, M., Aiello, E., Potter, J. D., & McTiernan, A.
- Affiliations
- Yale University (US)
- University of Washington (US)
- Corresponding author
- McTiernan, Anne
- ORCID
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2003-01-15
- Volume
- 289
- Issue
- 3
- Pages
- 323
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2110141259
- Cited by
- 517
- References
- 35
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 7 · 2023: 12 · 2022: 12 · 2021: 16 · 2020: 17 · 2019: 8 · 2018: 16 · 2017: 15 · 2016: 26 · 2015: 19 · 2014: 24 · 2013: 29 · 2012: 28
- FWCI
- 20.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (R01-69334)
- National Institute on Aging (AG1094)
- National Cancer Institute (T32 CA09661, T32CA009661)
- National Center for Research Resources (M01-RR 00037, M01RR000037)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Keywords
- physical activity, postmenopausal women, intra-abdominal fat, total body fat, subcutaneous abdominal fat, obesity, overweight, weight loss, moderate-intensity exercise, home-based exercise, walking, waist circumference, dose-response relationship, sedentary women
- MeSH terms
- Abdomen, Adipose Tissue, Aged, Body Composition, Female, Humans, Middle Aged, Obesity, Weight Loss, Exercise, Body Mass Index, Postmenopause
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