The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Mobilizing Patients in the Intensive Care Unit: Improving Neuromuscular Weakness and Physical Function
Abstract
Early mobilization of patients in the hospital and the intensive care unit has a strong historical precedent. However, in more recent times, deep sedation and bed rest have been part of routine medical care for many mechanically ventilated patients. A growing body of literature demonstrates that survivors of severe critical illness commonly have significant and prolonged neuromuscular complications that impair their physical function and quality of life after hospital discharge. Bed rest, and its associated mechanisms, may play an important role in the pathogenesis of neuromuscular weakness in critically ill patients. A new approach for managing mechanically ventilated patients includes reducing deep sedation and increasing rehabilitation therapy and mobilization soon after admission to the intensive care unit. Emerging research in this field provides preliminary evidence supporting the safety, feasibility, and potential benefits of early mobilization in critical care medicine.
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Cites
One-Year Outcomes in Survivors of the Acute Respiratory Distress Syndrome
Herridge, M. S., Cheung, A. M., Tansey, C. M., Matte-Martyn, A., Diaz-Granados, N., Al-Saidi, F., Cooper, A. B., Guest, C. B., Mazer, C. D., Mehta, S., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022450 · Cited by 2,334
Sandri, M., Lin, J., Handschin, C., Yang, W., Arany, Z. P., Lecker, S. H., Goldberg, A. L., & Spiegelman, B. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607795103 · Cited by 974
Two-Year Cognitive, Emotional, and Quality-of-Life Outcomes in Acute Respiratory Distress Syndrome
Hopkins, R. O., Weaver, L. K., Collingridge, D., Parkinson, R. B., Chan, K. J., & Orme, J. F. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200406-763oc · Cited by 759
Hermans, G., Wilmer, A., Meersseman, W., Milants, I., Wouters, P. J., Bobbaers, H., Bruyninckx, F., & Van den Berghe, G. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200605-665oc · Cited by 368
Lower limb skeletal muscle function after 6 wk of bed rest
Berg, H. E., Larsson, L., & Tesch, P. A. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.1.182 · Cited by 352
An overview of the issues: physiological effects of bed rest and restricted physical activity
CONVERTINO, V. A., BLOOMFIELD, S. A., & GREENLEAF, J. E. (1997) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199702000-00004 · Cited by 309 · cited 1×
“Even in these healthy volunteers, there is a prolonged recovery period required after cessation of bed rest before return to baseline status.(28,29) Clinical Presentation”
Background
Cited by
Spruit, M. A., Singh, S. J., Garvey, C., ZuWallack, R., Nici, L., Rochester, C., Hill, K., Holland, A. E., Lareau, S. C., Man, W. D.-C., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201309-1634st · Cited by 3,938
Needham, D. M., Davidson, J., Cohen, H., Hopkins, R. O., Weinert, C., Wunsch, H., Zawistowski, C., Bemis-Dougherty, A., Berney, S. C., Bienvenu, O. J., et al. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e318232da75 · Cited by 2,639
Self-citationLong-term cognitive impairment and functional disability among survivors of severe sepsis.
Iwashyna, T. J., Ely, E. W., Smith, D. M., & Langa, K. M. (2010) · JAMA · doi:10.1001/jama.2010.1553 · Cited by 2,582
Long-term complications of critical care
Desai, S. V., Law, T. J., & Needham, D. M. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181fd66e5 · Cited by 870
Self-citationAfilalo, J., Eisenberg, M. J., Morin, J.-F., Bergman, H., Monette, J., Noiseux, N., Perrault, L. P., Alexander, K. P., Langlois, Y., Dendukuri, N., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.06.039 · Cited by 746
Metadata
- Authors
- Needham, D. M.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2008-10-08
- Volume
- 300
- Issue
- 14
- Pages
- 1685
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W1990258338
- Cited by
- 471
- References
- 6
- FWCI
- 18.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- Needham, D. M. (2008). Mobilizing Patients in the Intensive Care Unit: Improving Neuromuscular Weakness and Physical Function. JAMA. https://doi.org/10.1001/jama.300.14.1685
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
