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Effectiveness of Tocilizumab in Patients Hospitalized With COVID-19: A Follow-up of the CORIMUNO-TOCI-1 Randomized Clinical Trial
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This follow-up study of the CORIMUNO-TOCI-1 randomized clinical trial examines the association between survival and C-reactive protein levels in patients hospitalized with COVID-19 who were treated with tocilizumab.
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COVID-19 TEDAVİSİNDE İLAÇ-İLAÇ ETKİLEŞİMLERİNİN FARMAKOKİNETİK AÇIDAN DEĞERLENDİRİLMESİ
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Metadata
- Authors
- Mariette, X., Hermine, O., Tharaux, P.-L., Resche-Rigon, M., Steg, P. G., Porcher, R., & Ravaud, P.
- Affiliations
- Department of Rheumatology, Hôpital Bicêtre, Assistance Publique–Hôpitaux de Paris, Le Kremlin Bicêtre, France
- Hôpital Necker-Enfants Malades (FR)
- Inserm (FR)
- Université de Paris, ECSTRRA Team, Centre of Research Epidemiology and Statistics, INSERM UMR1153, Paris, France
- Department of cardiology, Hôpital Bichat, Assistance Publique–Hôpitaux de Paris, Paris, France
- Venue
- JAMA Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 2021-09-01
- Volume
- 181
- Issue
- 9
- Pages
- 1241
- ISSN
- 2168-6106 (ISSN-L)
- PMC
- PMC8145157
- OpenAlex
- W3165791173
- Cited by
- 140
- References
- 7
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 15 · 2023: 31 · 2022: 50 · 2021: 31
- FWCI
- 10.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Internal Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- Sanofi
- Amarin Corporation
- Agence Nationale de la Recherche (ANR-10-IAHU-0001)
- Fondation pour la Recherche Médicale
- Servier
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Keywords
- tocilizumab, COVID-19 pandemic, C-reactive protein, survival, hospitalized patients, IL-6 receptor inhibition, cytokine storm
- MeSH terms
- COVID-19 Drug Treatment, Dose-Response Relationship, Drug, Follow-Up Studies, Humans, Intensive Care Units, Severity of Illness Index, Time Factors, Randomized Controlled Trials as Topic, Treatment Outcome, Antibodies, Monoclonal, Humanized
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